Bioconductor Task View: Bioinformatics

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Package Maintainer Title
ABarray Yongming Andrew Sun Microarray QA and statistical data analysis for Applied Biosystems Genome Survey Micorarray (AB1700) gene expression data.
ACME Sean Davis Algorithms for Calculating Microarray Enrichment (ACME)
adSplit Claudio Lottaz Annotation-Driven Clustering
affy Rafael A. Irizarry Methods for Affymetrix Oligonucleotide Arrays
affycomp Rafael A. Irizarry Graphics Toolbox for Assessment of Affymetrix Expression Measures
affyContam V. Carey structured corruption of affymetrix cel file data
AffyExpress Xuejun Arthur Li Affymetrix Quality Assessment and Analysis Tool
affyILM Myriam Kroll and Fabrice Berger Linear Model of background subtraction and the Langmuir isotherm
affylmGUI Keith Satterley GUI for affy analysis using limma package
affyPara Markus Schmidberger Parallelized preprocessing methods for Affymetrix Oligonucleotide Arrays
affypdnn Laurent Gautier Probe Dependent Nearest Neighbours (PDNN) for the affy package
affyPLM Ben Bolstad Methods for fitting probe-level models
affyQCReport Craig Parman QC Report Generation for affyBatch objects
AffyTiling Charles G. Danko Easy extraction of individual probes in Affymetrix tiling arrays
Agi4x44PreProcess Pedro Lopez-Romero PreProcessing of Agilent 4x44 array data
AgiMicroRna Pedro Lopez-Romero Processing and Differential Expression Analysis of Agilent microRNA chips
altcdfenvs Laurent Gautier alternative CDF environments (aka probeset mappings)
aroma.light Henrik Bengtsson Light-weight methods for normalization and visualization of microarray data using only basic R data types
arrayMvout V. Carey multivariate outlier detection for expression array QA
arrayQuality Agnes Paquet Assessing array quality on spotted arrays
arrayQualityMetrics Audrey Kauffmann Quality metrics on microarray data sets
ArrayTools Arthur Li geneChip Analysis Package
BAC Raphael Gottardo Bayesian Analysis of Chip-chip experiment
baySeq Thomas J. Hardcastle Empirical Bayesian analysis of patterns of differential expression in count data
BCRANK Adam Ameur Predicting binding site consensus from ranked DNA sequences
beadarray Mark Dunning Quality assessment and low-level analysis for Illumina BeadArray data
beadarraySNP Jan Oosting Normalization and reporting of Illumina SNP bead arrays
betr Martin Aryee Identify differentially expressed genes in microarray time-course data
bgafun Iain Wallace BGAfun A method to identify specifity determining residues in protein families
BGmix Alex Lewin Bayesian models for differential gene expression
BHC Rich Savage Bayesian Hierarchical Clustering
BicARE Pierre Gestraud Biclustering Analysis and Results Exploration
Biobase Biocore Team c/o BioC user list Biobase: Base functions for Bioconductor
BiocCaseStudies Biocore Team c/o BioC user list BiocCaseStudies: Support for the Case Studies Monograph
bioDist Biocore Team c/o BioC user list Different distance measures
BioNet Marcus Dittrich Routines for the functional analysis of biological networks
BioSeqClass Li Hong Classification for Biological Sequences
Biostrings H. Pages String objects representing biological sequences, and matching algorithms
BSgenome H. Pages Infrastructure for Biostrings-based genome data packages
BUS Yuanhua Liu Gene network reconstruction
CALIB Hui Zhao Calibration model for estimating absolute expression levels from microarray data
Category Biocore Team c/o BioC user list Category Analysis
cellHTS2 Florian Hahne Analysis of cell-based screens - revised version of cellHTS
CGEN William Wheeler An R package for analysis of case-control studies in genetic epidemiology
CGHcall Mark van de Wiel Calling aberrations for array CGH tumor profiles.
CGHnormaliter Bart P.P. van Houte Normalization of array CGH data with imbalanced aberrations.
charm Martin Aryee Analysis of DNA methylation data from CHARM microarrays
ChemmineR ChemmineR Team Analysis of Small Molecule and Screening Data
ChIPseqR Peter Humburg Identifying Protein Binding Sites in High-Throughput Sequencing Data
ChIPsim Peter Humburg Simulation of ChIP-seq experiments
clippda Stephen Nyangoma A package for the clinical proteomic profiling data analysis
Clonality Irina Ostrovnaya Clonality testing
clst Noah Hoffman Classification by local similarity threshold
clstutils Noah Hoffman Tools for performing taxonomic assignment.
clusterProfiler Guangchuang Yu statistical analysis and visulization of functional profiles for genes and gene clusters
clusterStab James W. MacDonald Compute cluster stability scores for microarray data
CMA Christoph Bernau Synthesis of microarray-based classification
cn.farms Andreas Mitterecker , Djork-Arne Clevert cn.farms - Factor Analysis for copy number estimation
CoCiteStats Biocore Team c/o BioC user list Different test statistics based on co-citation.
codelink Diego Diez Manipulation of Codelink Bioarrays data.
CoGAPS Elana J. Fertig , Michael F. Ochs Coordinated Gene Activity in Pattern Sets
ConsensusClusterPlus Matt Wilkerson ConsensusClusterPlus
CORREP Dongxiao Zhu Multivariate Correlation Estimator and Statistical Inference Procedures.
cosmo Oliver Bembom Supervised detection of conserved motifs in DNA sequences
cosmoGUI Oliver Bembom GUI for constructing constraint sets used by the cosmo package
CRImage Henrik Failmezger , Yinyin Yuan CRImage a package to classify cells and calculate tumour cellularity
crlmm Benilton S Carvalho , Robert Scharpf , Matt Ritchie Genotype Calling (CRLMM) and Copy Number Analysis tool for Affymetrix SNP 5.0 and 6.0 and Illumina arrays.
ctc Antoine Lucas Cluster and Tree Conversion.
cycle Matthias Futschik Significance of periodic expression pattern in time-series data
daMA Jobst Landgrebe Efficient design and analysis of factorial two-colour microarray data
DEDS Yuanyuan Xiao Differential Expression via Distance Summary for Microarray Data
DEGraph Laurent Jacob Two-sample tests on a graph
DEGseq Likun Wang Identify Differentially Expressed Genes from RNA-seq data
DFP Rodrigo Alvarez-Glez Gene Selection
diffGeneAnalysis Choudary Jagarlamudi Performs differential gene expression Analysis
domainsignatures Florian Hahne Geneset enrichment based on InterPro domain signatures
dualKS Eric J. Kort Dual KS Discriminant Analysis and Classification
dyebias Philip Lijnzaad The GASSCO method for correcting for slide-dependent gene-specific dye bias
EBarrays Ming Yuan Unified Approach for Simultaneous Gene Clustering and Differential Expression Identification
edd Vince Carey expression density diagnostics
edgeR Mark Robinson , Davis McCarthy , Gordon Smyth Empirical analysis of digital gene expression data in R
eisa Gabor Csardi Expression data analysis via the Iterative Signature Algorithm
ExiMiR Sylvain Gubian R functions for the normalization of Exiqon miRNA array data
exonmap Crispin Miller High level analysis of Affymetrix exon array data (DEPRECATED please use xmapcore)
ExpressionView Gabor Csardi Visualize biclusters identified in gene expression data
fabia Sepp Hochreiter FABIA: Factor Analysis for Bicluster Acquisition
factDesign Denise Scholtens Factorial designed microarray experiment analysis
farms Djork-Arne Clevert FARMS - Factor Analysis for Robust Microarray Summarization
fdrame Effi Kenigsberg FDR adjustments of Microarray Experiments (FDR-AME)
flagme Mark Robinson Analysis of Metabolomics GC/MS Data
flowClust Raphael Gottardo Clustering for Flow Cytometry
flowFP Herb Holyst Fingerprinting for Flow Cytometry
flowMeans Nima Aghaeepour Non-parametric Flow Cytometry Data Gating
flowMerge Greg Finak Cluster Merging for Flow Cytometry Data
flowPhyto David M. Schruth Methods for Continuous Flow Cytometry
flowStats Florian Hahne and Chao-Jen Wong Statistical methods for the analysis of flow cytometry data
flowTrans Greg Finak Parameter Optimization for Flow Cytometry Data Transformation
frma Matthew N. McCall Frozen RMA and Barcode
frmaTools Matthew N. McCall Frozen RMA Tools
gaga David Rossell GaGa hierarchical model for microarray data analysis
gage Weijun Luo Generally Applicable Gene-set Enrichment for Pathway Analysis
gcrma Z. Wu Background Adjustment Using Sequence Information
genArise IFC Development Team Microarray Analysis tool
gene2pathway Holger Froehlich Prediction of KEGG pathway membership for individual genes based on InterPro domain signatures
genefilter Biocore Team c/o BioC user list genefilter: methods for filtering genes from microarray experiments
GeneMeta Biocore Team c/o BioC user list MetaAnalysis for High Throughput Experiments
geneRecommender Greg Hather A gene recommender algorithm to identify genes coexpressed with a query set of genes
GeneSelectMMD Weiliang Qiu Gene selection based on the marginal distributions of gene profiles that characterized by a mixture of three-component multivariate distributions
GGBase Vince Carey infrastructure for genetics of gene expression (c) 2008 VJ Carey
GGtools Vince Carey software and data for genetics of gene expression (c) 2006 VJ Carey
GlobalAncova Manuela Hummel Calculates a global test for differential gene expression between groups
globaltest Jelle Goeman Testing groups of covariates/features for association with a response variable, with applications to gene set testing
GOSemSim Guangchuang Yu GO-terms Semantic Similarity Measures
GOstats Biocore Team c/o BioC user list Tools for manipulating GO and microarrays.
gpls Biocore Team c/o BioC user list Classification using generalized partial least squares
GraphAT Thomas LaFramboise Graph Theoretic Association Tests
GSEABase Biocore Team c/o BioC user list Gene set enrichment data structures and methods
GSEAlm Assaf Oron Linear Model Toolset for Gene Set Enrichment Analysis
GSRI Julian Gehring Gene Set Regulation Index
Harshlight Maurizio Pellegrino A "corrective make-up" program for microarray chips
HELP Reid F. Thompson Tools for HELP data analysis
HEM HyungJun Cho Heterogeneous error model for identification of differentially expressed genes under multiple conditions
hopach Katherine S. Pollard Hierarchical Ordered Partitioning and Collapsing Hybrid (HOPACH)
HTqPCR Heidi Dvinge Automated analysis of high-throughput qPCR data
HTSanalyzeR Xin Wang Gene set over-representation, enrichment and network analyses for high-throughput screens
ibh Kircicegi Korkmaz Interaction Based Homogeneity for Evaluating Gene Lists
Icens Biocore Team c/o BioC user list NPMLE for Censored and Truncated Data
iChip Qianxing Mo Bayesian Modeling of ChIP-chip Data Through Hidden Ising Models
iFlow Kyongryun Lee GUI based visualization for flow cytometry
imageHTS Gregoire Pau Analysis of high-throughput microscopy-based screens
impute Balasubramanian Narasimhan impute: Imputation for microarray data
iSeq Qianxing Mo Bayesian Hierarchical Modeling of ChIP-seq Data Through Hidden Ising Models
iterativeBMA Ka Yee Yeung The Iterative Bayesian Model Averaging (BMA) algorithm
iterativeBMAsurv Ka Yee Yeung The Iterative Bayesian Model Averaging (BMA) Algorithm For Survival Analysis
joda Ewa Szczurek JODA algorithm for quantifying gene deregulation using knowledge
lapmix Yann Ruffieux Laplace Mixture Model in Microarray Experiments
LBE Cyril Dalmasso Estimation of the false discovery rate.
les Julian Gehring Identifying Differential Effects in Tiling Microarray Data
limma Gordon Smyth Linear Models for Microarray Data
limmaGUI Keith Satterley GUI for limma package
LiquidAssociation Yen-Yi Ho LiquidAssociation
LMGene Blythe Durbin-Johnson LMGene Software for Data Transformation and Identification of Differentially Expressed Genes in Gene Expression Arrays
logicFS Holger Schwender Identification of SNP Interactions
LPE Nitin Jain Methods for analyzing microarray data using Local Pooled Error (LPE) method
LPEadj Carl Murie A correction of the local pooled error (LPE) method to replace the asymptotic variance adjustment with an unbiased adjustment based on sample size.
lumi Pan Du BeadArray Specific Methods for Illumina Methylation and Expression Microarrays
LVSmiRNA Stefano Calza LVS normalization for Agilent miRNA data
maanova Keith Sheppard Tools for analyzing Micro Array experiments
maCorrPlot Alexander Ploner Visualize artificial correlation in microarray data
made4 Aedin Culhane Multivariate analysis of microarray data using ADE4
maigesPack Gustavo H. Esteves Functions to handle cDNA microarray data, including several methods of data analysis
makecdfenv James W. MacDonald CDF Environment Maker
makePlatformDesign Benilton Carvalho Platform Design Package
MANOR Pierre Neuvial CGH Micro-Array NORmalization
MantelCorr Brian Steinmeyer Compute Mantel Cluster Correlations
marray Yee Hwa (Jean) Yang Exploratory analysis for two-color spotted microarray data
maSigPro Ana Conesa Significant Gene Expression Profile Differences in Time Course Microarray Data
MBCB Jeff Allen MBCB (Model-based Background Correction for Beadarray)
mBPCR P.M.V. Rancoita Bayesian Piecewise Constant Regression for DNA copy number estimation
mcaGUI Wade K. Copeland Microbial Community Analysis GUI
MCRestimate Marc Johannes Misclassification error estimation with cross-validation
mdqc Gabriela Cohen-Freue Mahalanobis Distance Quality Control for microarrays
MeasurementError.cor Beiying Ding Measurement Error model estimate for correlation coefficient
MEDIPS Lukas Chavez MeDIP-Seq data analysis
metaArray Hyungwon Choi Integration of Microarray Data for Meta-analysis
metahdep John R. Stevens Hierarchical Dependence in Meta-Analysis
methVisual Arie Zackay Methods for visualization and statistics on DNA methylation data
methylumi Sean Davis Handle Illumina methylation data
Mfuzz Matthias Futschik Soft clustering of time series gene expression data
MiChip Jonathon Blake MiChip Parsing and Summarizing Functions
microRNA Chao-Jen Wong Data and functions for dealing with microRNAs
MiPP Sukwoo Kim Misclassification Penalized Posterior Classification
miRNApath James M. Ward miRNApath: Pathway Enrichment for miRNA Expression Data
MLInterfaces V. Carey Uniform interfaces to R machine learning procedures for data in Bioconductor containers
mosaics Dongjun Chung MOSAiCS (MOdel-based one and two Sample Analysis and Inference for ChIP-Seq)
MSnbase Laurent Gatto MSnbase: Base Functions and Classes for MS-based Proteomics
Mulcom Claudio Isella Calculates MulCom test
multiscan Mizanur Khondoker R package for combining multiple scans
multtest Katherine S. Pollard Resampling-based multiple hypothesis testing
nem Christian Bender Nested Effects Models to reconstruct phenotypic hierarchies
netresponse Leo Lahti NetResponse: functional network analysis
nnNorm Adi Laurentiu Tarca Spatial and intensity based normalization of cDNA microarray data based on robust neural nets
NTW Yuanhua Liu Predict gene network using an Ordinary Differential Equation (ODE) based method
NuPoP Ji-Ping Wang An R package for nucleosome positioning prediction
occugene Oliver Will Functions for Multinomial Occupancy Distribution
OCplus Alexander Ploner Operating characteristics plus sample size and local fdr for microarray experiments
oligo Benilton Carvalho Preprocessing tools for oligonucleotide arrays.
OLIN Matthias Futschik Optimized local intensity-dependent normalisation of two-color microarrays
OLINgui Matthias Futschik Graphical user interface for OLIN
oneChannelGUI Raffaele A Calogero This package extends the capabilities of affylmGUI graphical interface. Affymetrix 3' IVT, gene an exon arrays are actually implemented togheter with Illumina, GEO matrix series files and tab delimited files. Next Generation Sequencing secondary analysis for ncRNA quantification is also available.
ontoCAT Natalja Kurbatova Ontology traversal and search
OrderedList Claudio Lottaz Similarities of Ordered Gene Lists
OTUbase Daniel Beck Provides structure and functions for the analysis of OTU data
OutlierD Sukwoo Kim Outlier detection using quantile regression on the M-A scatterplots of high-throughput data
pamr Rob Tibshirani Pam: prediction analysis for microarrays
parody VJ Carey Parametric And Resistant Outlier DYtection
PatientGeneSets Simina M. Boca Patient-oriented gene-set analysis
pcaMethods Wolfram Stacklies A collection of PCA methods.
pdmclass James W. MacDonald Classification of Microarray Samples using Penalized Discriminant Methods
phenoDist Xian Zhang Phenotypic distance measures
phenoTest Evarist Planet Tools to test correlation between gene expression and phenotype.
PICS Arnaud Droit , Xuekui Zhang , Raphael Gottardo Probabilistic inference of ChIP-seq
plw Magnus Astrand Probe level Locally moderated Weighted t-tests.
procoil Ulrich Bodenhofer Prediction of Oligomerization of Coiled Coil Proteins
PROMISE Xueyuan Cao PRojection Onto the Most Interesting Statistical Evidence
puma Richard Pearson , Li Zhang Propagating Uncertainty in Microarray Analysis
pvac Jun Lu , Pierre R. Bushel PCA-based gene filtering for Affymetrix arrays
qpcrNorm Jessica Mar Data-driven normalization strategies for high-throughput qPCR data.
qpgraph Robert Castelo Reverse engineering of molecular regulatory networks with qp-graphs
qvalue John D. Storey Q-value estimation for false discovery rate control
R453Plus1Toolbox Hans-Ulrich Klein A package for importing and analyzing data from Roche's Genome Sequencer System.
rama Raphael Gottardo Robust Analysis of MicroArrays
RBioinf Robert Gentleman RBioinf
rbsurv Soo-heang Eo Robust likelihood-based survival modeling with microarray data
RefPlus Kai-Ming Chang A function set for the Extrapolation Strategy (RMA+) and Extrapolation Averaging (RMA++) methods.
rflowcyt N. LeMeur Statistical tools and data structures for analytic flow cytometry
rHVDM Martino Barenco Hidden Variable Dynamic Modeling
Ringo J. Toedling R Investigation of ChIP-chip Oligoarrays
Rmagpie Camille Maumet MicroArray Gene-expression-based Program In Error rate estimation
rMAT Arnaud Droit and Raphael Gottardo R implementation from MAT program to normalize and analyze tiling arrays and ChIP-chip data.
RmiR Francesco Favero Package to work with miRNAs and miRNA targets with R
RNAinteract Bernd Fischer Estimate Pairwise Interactions from multidimensional features
RNAither Nora Rieber Statistical analysis of high-throughput RNAi screens
rnaSeqMap Michal Okoniewski rnaSeq analyses using xmapcore database
ROC Vince Carey utilities for ROC, with uarray focus
Rolexa Jacques Rougemont Statistical analysis of Solexa sequencing data
RPA Leo Lahti RPA: probe reliability and differential gene expression analysis
RTCA Jitao David Zhang Open-source toolkit to analyse data from xCELLigence System (RTCA) by Roche
RTools4TB Aurelie Bergon Data mining of public microarray data through connections to the TranscriptomeBrowser database.
Rtreemix Jasmina Bogojeska Rtreemix: Mutagenetic trees mixture models.
SAGx Per Broberg, Statistical Analysis of the GeneChip
SamSPECTRAL Habil Zare Identifies cell population in flow cytometry data.
segmentSeq Thomas J. Hardcastle Methods for identifying small RNA loci from high-throughput sequencing data
seqLogo Oliver Bembom Sequence logos for DNA sequence alignments
ShortRead Biocore Team c/o BioC user list Classes and methods for high-throughput short-read sequencing data.
siggenes Holger Schwender Multiple testing using SAM and Efron's empirical Bayes approaches
sigPathway Weil Lai Pathway Analysis
SIM Maarten van Iterson Integrated Analysis on two human genomic datasets
simpleaffy Crispin Miller Very simple high level analysis of Affymetrix data
sizepower Weiliang Qiu Sample Size and Power Calculation in Micorarray Studies
SLqPCR Matthias Kohl Functions for analysis of real-time quantitative PCR data at SIRS-Lab GmbH
snapCGH John Marioni Segmentation, normalisation and processing of aCGH data.
snm Brig Mecham Supervised Normalization of Microarrays
SpeCond Florence Cavalli Condition specific detection from expression data
spikeLI Enrico Carlon Affymetrix Spike-in Langmuir Isotherm Data Analysis Tool
spotSegmentation Chris Fraley Microarray Spot Segmentation and Gridding for Blocks of Microarray Spots
sscore Richard Kennedy S-Score Algorithm for Affymetrix Oligonucleotide Microarrays
ssize Gregory R. Warnes Estimate Microarray Sample Size
Starr Benedikt Zacher Simple tiling array analysis of Affymetrix ChIP-chip data
stepNorm Yuanyuan Xiao Stepwise normalization functions for cDNA microarrays
TargetSearch Alvaro Cuadros-Inostroza A package for the analysis of GC-MS metabolite profiling data.
TDARACNE Zoppoli Pietro Network reverse engineering from time course data.
TEQC Manuela Hummel Quality control for target capture experiments
tigre Antti Honkela Transcription factor Inference through Gaussian process Reconstruction of Expression
tilingArray Zhenyu Xu Transcript mapping with high-density oligonucleotide tiling arrays
timecourse Yu Chuan Tai Statistical Analysis for Developmental Microarray Time Course Data
topGO Adrian Alexa topGO: Enrichment analysis for Gene Ontology
tspair Jeffrey T. Leek Top Scoring Pairs for Microarray Classification
TurboNorm Maarten van Iterson A fast scatterplot smoother suitable for microarray normalization
twilight Stefanie Scheid Estimation of local false discovery rate
VanillaICE Robert Scharpf A Hidden Markov Model for high throughput genotyping arrays
vbmp Nicola Lama Variational Bayesian Multinomial Probit Regression
vsn Wolfgang Huber Variance stabilization and calibration for microarray data
XDE Robert Scharpf XDE: a Bayesian hierarchical model for cross-study analysis of differential gene expression
xmapcore Tim Yates Core access to the xmap database (installed separately)
xps Christian Stratowa Processing and Analysis of Affymetrix Oligonucleotide Arrays including Exon Arrays, Whole Genome Arrays and Plate Arrays
yaqcaffy Laurent Gatto Affymetrix expression data quality control and reproducibility analysis