To install this package, start R and enter:

## try http:// if https:// URLs are not supported
source("https://bioconductor.org/biocLite.R")
biocLite("cosmo")

In most cases, you don't need to download the package archive at all.

cosmo

   

This package is for version 2.8 of Bioconductor; for the stable, up-to-date release version, see cosmo.

Supervised detection of conserved motifs in DNA sequences

Bioconductor version: 2.8

cosmo searches a set of unaligned DNA sequences for a shared motif that may, for example, represent a common transcription factor binding site. The algorithm is similar to MEME, but also allows the user to specify a set of constraints that the position weight matrix of the unknown motif must satisfy. Such constraints may include bounds on the information content across certain regions of the unknown motif, for example, and can often be formulated on the basis of prior knowledge about the structure of the transcription factor in question. The unknown motif width, the distribution of motif occurrences (OOPS, ZOOPS, or TCM), as well as the appropriate constraint set can be selected data-adaptively.

Author: Oliver Bembom, Fabian Gallusser, and Sandrine Dudoit

Maintainer: Oliver Bembom <oliver.bembom at gmail.com>

Citation (from within R, enter citation("cosmo")):

Installation

To install this package, start R and enter:

## try http:// if https:// URLs are not supported
source("https://bioconductor.org/biocLite.R")
biocLite("cosmo")

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("cosmo")

 

PDF cosmo.pdf
PDF   Reference Manual

Details

biocViews SequenceMatching, Software
Version 1.18.0
In Bioconductor since BioC 2.0 (R-2.5) (9 years)
License file LICENSE
Depends R (>= 2.4.0), methods, utils, seqLogo
Imports
LinkingTo
Suggests cosmoGUI
SystemRequirements
Enhances
URL http://cosmoweb.berkeley.edu/intro.html http://www.bepress.com/sagmb/vol6/iss1/art8
Depends On Me cosmoGUI
Imports Me
Suggests Me mosaics
Build Report  

Package Archives

Follow Installation instructions to use this package in your R session.

Package Source cosmo_1.18.0.tar.gz
Windows Binary cosmo_1.18.0.zip (32- & 64-bit)
Mac OS X 10.6 (Snow Leopard)
Mac OS X 10.9 (Mavericks)
Subversion source (username/password: readonly)
Git source https://github.com/Bioconductor-mirror/cosmo/tree/release-2.8
Package Short Url http://bioconductor.org/packages/cosmo/
Package Downloads Report Download Stats

Documentation »

Bioconductor

R / CRAN packages and documentation

Support »

Please read the posting guide. Post questions about Bioconductor to one of the following locations:

Fred Hutchinson Cancer Research Center