Bioconductor 3.23 Release Schedule

MeLSI

This is the development version of MeLSI; to use it, please install the devel version of Bioconductor.

Metric Learning for Statistical Inference in Microbiome Analysis


Bioconductor version: Development (3.23)

MeLSI (Metric Learning for Statistical Inference) is a novel machine learning method for microbiome data analysis that learns optimal distance metrics to improve statistical power in detecting group differences. Unlike traditional distance metrics (Bray-Curtis, Euclidean, Jaccard), MeLSI adapts to the specific characteristics of your dataset to maximize separation between groups. The method uses an ensemble of weak learners to identify which microbial features drive group differences, providing both improved statistical power and biological interpretability through feature importance weights.

Author: Nathan Bresette [aut, cre] ORCID iD ORCID: 0009-0003-1554-6006 , Aaron C. Ericsson [aut] ORCID iD ORCID: 0000-0002-3053-7269 , Carter Woods [aut] ORCID iD ORCID: 0009-0007-5345-2712 , Ai-Ling Lin [aut, fnd] ORCID iD ORCID: 0000-0002-5197-2219

Maintainer: Nathan Bresette <nathanbresette04 at gmail.com>

Citation (from within R, enter citation("MeLSI")):

Installation

To install this package, start R (version "4.6") and enter:


if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

# The following initializes usage of Bioc devel
BiocManager::install(version='devel')

BiocManager::install("MeLSI")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("MeLSI")
MeLSI Tutorial HTML R Script
Reference Manual PDF
NEWS Text
LICENSE Text

Details

biocViews Microbiome, Software, StatisticalMethod
Version 0.99.8
In Bioconductor since BioC 3.23 (R-4.6)
License MIT + file LICENSE
Depends R (>= 4.6.0)
Imports vegan, ggplot2, phyloseq, stats, utils
System Requirements
URL https://github.com/NathanBresette/MeLSI
Bug Reports https://github.com/NathanBresette/MeLSI/issues
See More
Suggests testthat, knitr, rmarkdown, BiocManager, BiocStyle, BiocParallel, Matrix, microbiome
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Package Archives

Follow Installation instructions to use this package in your R session.

Source Package MeLSI_0.99.8.tar.gz
Windows Binary (x86_64)
macOS Binary (big-sur-x86_64)
macOS Binary (big-sur-arm64)
macOS Binary (sonoma-arm64)
Source Repository git clone https://git.bioconductor.org/packages/MeLSI
Source Repository (Developer Access) git clone git@git.bioconductor.org:packages/MeLSI
Bioc Package Browser https://code.bioconductor.org/browse/MeLSI/
Package Short Url https://bioconductor.org/packages/MeLSI/
Package Downloads Report Download Stats