Bioconductor 3.22 Released

DegCre

This is the development version of DegCre; for the stable release version, see DegCre.

Probabilistic association of DEGs to CREs from differential data


Bioconductor version: Development (3.23)

DegCre generates associations between differentially expressed genes (DEGs) and cis-regulatory elements (CREs) based on non-parametric concordance between differential data. The user provides GRanges of DEG TSS and CRE regions with differential p-value and optionally log-fold changes and DegCre returns an annotated Hits object with associations and their calculated probabilities. Additionally, the package provides functionality for visualization and conversion to other formats.

Author: Brian S. Roberts [aut, cre] ORCID iD ORCID: 0009-0001-2914-6826

Maintainer: Brian S. Roberts <brianroberts1976 at yahoo.com>

Citation (from within R, enter citation("DegCre")):

Installation

To install this package, start R (version "4.6") and enter:


if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

# The following initializes usage of Bioc devel
BiocManager::install(version='devel')

BiocManager::install("DegCre")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

Reference Manual PDF

Details

biocViews ATACSeq, ChIPSeq, DNaseSeq, GeneExpression, GeneRegulation, RNASeq, Software
Version 1.5.1
In Bioconductor since BioC 3.19 (R-4.4) (1.5 years)
License MIT + file LICENSE
Depends R (>= 4.4)
Imports GenomicRanges, InteractionSet, plotgardener, S4Vectors, stats, graphics, grDevices, BiocGenerics, Seqinfo, IRanges, BiocParallel, qvalue, TxDb.Hsapiens.UCSC.hg38.knownGene, org.Hs.eg.db, utils
System Requirements
URL https://github.com/brianSroberts/DegCre
Bug Reports https://github.com/brianSroberts/DegCre/issues
See More
Suggests BSgenome, BSgenome.Hsapiens.UCSC.hg38, BiocStyle, magick, knitr, rmarkdown, TxDb.Mmusculus.UCSC.mm10.knownGene, testthat (>= 3.0.0)
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Follow Installation instructions to use this package in your R session.

Source Package
Windows Binary (x86_64)
macOS Binary (x86_64)
macOS Binary (arm64)
Source Repository git clone https://git.bioconductor.org/packages/DegCre
Source Repository (Developer Access) git clone git@git.bioconductor.org:packages/DegCre
Package Short Url https://bioconductor.org/packages/DegCre/
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