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This page was generated on 2024-12-23 12:05 -0500 (Mon, 23 Dec 2024).

HostnameOSArch (*)R versionInstalled pkgs
nebbiolo2Linux (Ubuntu 24.04.1 LTS)x86_644.4.2 (2024-10-31) -- "Pile of Leaves" 4744
palomino8Windows Server 2022 Datacenterx644.4.2 (2024-10-31 ucrt) -- "Pile of Leaves" 4487
merida1macOS 12.7.5 Montereyx86_644.4.2 (2024-10-31) -- "Pile of Leaves" 4515
kjohnson1macOS 13.6.6 Venturaarm644.4.2 (2024-10-31) -- "Pile of Leaves" 4467
Click on any hostname to see more info about the system (e.g. compilers)      (*) as reported by 'uname -p', except on Windows and Mac OS X

Package 1609/2289HostnameOS / ArchINSTALLBUILDCHECKBUILD BIN
ProteoDisco 1.12.0  (landing page)
Job van Riet
Snapshot Date: 2024-12-19 13:00 -0500 (Thu, 19 Dec 2024)
git_url: https://git.bioconductor.org/packages/ProteoDisco
git_branch: RELEASE_3_20
git_last_commit: 89c9e43
git_last_commit_date: 2024-10-29 11:03:45 -0500 (Tue, 29 Oct 2024)
nebbiolo2Linux (Ubuntu 24.04.1 LTS) / x86_64  OK    OK    WARNINGS  UNNEEDED, same version is already published
palomino8Windows Server 2022 Datacenter / x64  OK    OK    WARNINGS    OK  UNNEEDED, same version is already published
merida1macOS 12.7.5 Monterey / x86_64  OK    ERROR  skippedskipped
kjohnson1macOS 13.6.6 Ventura / arm64  OK    ERROR  skippedskipped


CHECK results for ProteoDisco on palomino8

To the developers/maintainers of the ProteoDisco package:
- Allow up to 24 hours (and sometimes 48 hours) for your latest push to git@git.bioconductor.org:packages/ProteoDisco.git to reflect on this report. See Troubleshooting Build Report for more information.
- Use the following Renviron settings to reproduce errors and warnings.
- If 'R CMD check' started to fail recently on the Linux builder(s) over a missing dependency, add the missing dependency to 'Suggests:' in your DESCRIPTION file. See Renviron.bioc for more information.

raw results


Summary

Package: ProteoDisco
Version: 1.12.0
Command: F:\biocbuild\bbs-3.20-bioc\R\bin\R.exe CMD check --no-multiarch --install=check:ProteoDisco.install-out.txt --library=F:\biocbuild\bbs-3.20-bioc\R\library --no-vignettes --timings ProteoDisco_1.12.0.tar.gz
StartedAt: 2024-12-20 04:50:00 -0500 (Fri, 20 Dec 2024)
EndedAt: 2024-12-20 05:01:32 -0500 (Fri, 20 Dec 2024)
EllapsedTime: 692.3 seconds
RetCode: 0
Status:   WARNINGS  
CheckDir: ProteoDisco.Rcheck
Warnings: 2

Command output

##############################################################################
##############################################################################
###
### Running command:
###
###   F:\biocbuild\bbs-3.20-bioc\R\bin\R.exe CMD check --no-multiarch --install=check:ProteoDisco.install-out.txt --library=F:\biocbuild\bbs-3.20-bioc\R\library --no-vignettes --timings ProteoDisco_1.12.0.tar.gz
###
##############################################################################
##############################################################################


* using log directory 'F:/biocbuild/bbs-3.20-bioc/meat/ProteoDisco.Rcheck'
* using R version 4.4.2 (2024-10-31 ucrt)
* using platform: x86_64-w64-mingw32
* R was compiled by
    gcc.exe (GCC) 13.3.0
    GNU Fortran (GCC) 13.3.0
* running under: Windows Server 2022 x64 (build 20348)
* using session charset: UTF-8
* using option '--no-vignettes'
* checking for file 'ProteoDisco/DESCRIPTION' ... OK
* checking extension type ... Package
* this is package 'ProteoDisco' version '1.12.0'
* package encoding: UTF-8
* checking package namespace information ... OK
* checking package dependencies ... OK
* checking if this is a source package ... OK
* checking if there is a namespace ... OK
* checking for hidden files and directories ... OK
* checking for portable file names ... OK
* checking whether package 'ProteoDisco' can be installed ... WARNING
Found the following significant warnings:
  Warning: replacing previous import 'dplyr::rename' by 'plyr::rename' when loading 'ProteoDisco'
  Warning: replacing previous import 'dplyr::count' by 'plyr::count' when loading 'ProteoDisco'
  Warning: replacing previous import 'dplyr::failwith' by 'plyr::failwith' when loading 'ProteoDisco'
  Warning: replacing previous import 'dplyr::id' by 'plyr::id' when loading 'ProteoDisco'
  Warning: replacing previous import 'dplyr::summarize' by 'plyr::summarize' when loading 'ProteoDisco'
  Warning: replacing previous import 'dplyr::summarise' by 'plyr::summarise' when loading 'ProteoDisco'
  Warning: replacing previous import 'dplyr::mutate' by 'plyr::mutate' when loading 'ProteoDisco'
  Warning: replacing previous import 'dplyr::desc' by 'plyr::desc' when loading 'ProteoDisco'
  Warning: replacing previous import 'dplyr::arrange' by 'plyr::arrange' when loading 'ProteoDisco'
See 'F:/biocbuild/bbs-3.20-bioc/meat/ProteoDisco.Rcheck/00install.out' for details.
* checking installed package size ... OK
* checking package directory ... OK
* checking 'build' directory ... OK
* checking DESCRIPTION meta-information ... OK
* checking top-level files ... OK
* checking for left-over files ... OK
* checking index information ... OK
* checking package subdirectories ... OK
* checking code files for non-ASCII characters ... OK
* checking R files for syntax errors ... OK
* checking whether the package can be loaded ... OK
* checking whether the package can be loaded with stated dependencies ... OK
* checking whether the package can be unloaded cleanly ... OK
* checking whether the namespace can be loaded with stated dependencies ... NOTE
Warning: no function found corresponding to methods exports from 'ProteoDisco' for: 'show'

A namespace must be able to be loaded with just the base namespace
loaded: otherwise if the namespace gets loaded by a saved object, the
session will be unable to start.

Probably some imports need to be declared in the NAMESPACE file.
* checking whether the namespace can be unloaded cleanly ... OK
* checking dependencies in R code ... OK
* checking S3 generic/method consistency ... OK
* checking replacement functions ... OK
* checking foreign function calls ... OK
* checking R code for possible problems ... OK
* checking Rd files ... NOTE
checkRd: (-1) checkProteotypicFragments.Rd:25: Lost braces; missing escapes or markup?
    25 | \item{x}{({ProteoDiscography}): ProteoDiscography object which stores the annotation and genomic sequences.}
       |           ^
checkRd: (-1) checkProteotypicFragments.Rd:39: Lost braces; missing escapes or markup?
    39 | {ProteoDiscography} with an additional column specifying the number of proteotypic fragments per record.
       | ^
checkRd: (-1) generateJunctionModels.Rd:36: Lost braces; missing escapes or markup?
    36 | of the given {ProteoDiscography}; strand-information is taken into account. If no strand-information is given, the nearest (or overlapping) known
       |              ^
checkRd: (-1) importGenomicVariants.MAF.Rd:17: Lost braces; missing escapes or markup?
    17 | \item{ProteoDiscography}{({ProteoDiscography}): ProteoDiscography object which stores the annotation and genomic sequences.}
       |                           ^
checkRd: (-1) importGenomicVariants.Rd:40: Lost braces; missing escapes or markup?
    40 | into the {ProteoDiscography} as a {VRanges}. This genomic variants can later be incorporated within transcript 
       |          ^
checkRd: (-1) importGenomicVariants.Rd:40: Lost braces; missing escapes or markup?
    40 | into the {ProteoDiscography} as a {VRanges}. This genomic variants can later be incorporated within transcript 
       |                                   ^
checkRd: (-1) importGenomicVariants.Rd:19: Lost braces; missing escapes or markup?
    19 | \item{ProteoDiscography}{({ProteoDiscography}): ProteoDiscography object which stores the annotation and genomic sequences.}
       |                           ^
checkRd: (-1) importGenomicVariants.VCF.Rd:17: Lost braces; missing escapes or markup?
    17 | \item{ProteoDiscography}{({ProteoDiscography}): ProteoDiscography object which stores the annotation and genomic sequences.}
       |                           ^
checkRd: (-1) importSpliceJunctions.Rd:39: Lost braces; missing escapes or markup?
    39 | Input should be a {tibble} containing the following columns:
       |                   ^
checkRd: (-1) importSpliceJunctions.Rd:18: Lost braces; missing escapes or markup?
    18 | \item{ProteoDiscography}{({ProteoDiscography}): ProteoDiscography object which stores the annotation and genomic sequences.}
       |                           ^
checkRd: (-1) importTranscriptSequences.Rd:15: Lost braces; missing escapes or markup?
    15 | \item{ProteoDiscography}{({ProteoDiscography}): ProteoDiscography object which stores the annotation and genomic sequences.}
       |                           ^
checkRd: (-1) incorporateGenomicVariants.Rd:34: Lost braces; missing escapes or markup?
    34 | \code{incorporateMutations} Incorporates SNV, MNV and InDels present in the {ProteoDiscography} on the transcripts.
       |                                                                             ^
checkRd: (-1) incorporateGenomicVariants.Rd:17: Lost braces; missing escapes or markup?
    17 | \item{ProteoDiscography}{({ProteoDiscography}): ProteoDiscography object which stores the annotation and genomic sequences.}
       |                           ^
* checking Rd metadata ... OK
* checking Rd cross-references ... OK
* checking for missing documentation entries ... WARNING
Undocumented S4 methods:
  generic 'show' and siglist 'ProteoDiscography'
All user-level objects in a package (including S4 classes and methods)
should have documentation entries.
See chapter 'Writing R documentation files' in the 'Writing R
Extensions' manual.
* checking for code/documentation mismatches ... OK
* checking Rd \usage sections ... OK
* checking Rd contents ... OK
* checking for unstated dependencies in examples ... OK
* checking contents of 'data' directory ... OK
* checking data for non-ASCII characters ... NOTE
  Error loading dataset 'ProteoDiscographyExample.hg19':
   Error in h(simpleError(msg, call)) : 
    error in evaluating the argument 'x' in selecting a method for function 'seqlevels': UCSC library operation failed
  
* checking data for ASCII and uncompressed saves ... OK
* checking installed files from 'inst/doc' ... OK
* checking files in 'vignettes' ... OK
* checking examples ... OK
Examples with CPU (user + system) or elapsed time > 5s
                            user system elapsed
incorporateGenomicVariants 41.00   1.25   42.25
generateJunctionModels     15.03   0.78   39.73
* checking for unstated dependencies in 'tests' ... OK
* checking tests ...
  Running 'testthat.R'
 OK
* checking for unstated dependencies in vignettes ... OK
* checking package vignettes ... OK
* checking running R code from vignettes ... SKIPPED
* checking re-building of vignette outputs ... SKIPPED
* checking PDF version of manual ... OK
* DONE

Status: 2 WARNINGs, 3 NOTEs
See
  'F:/biocbuild/bbs-3.20-bioc/meat/ProteoDisco.Rcheck/00check.log'
for details.


Installation output

ProteoDisco.Rcheck/00install.out

##############################################################################
##############################################################################
###
### Running command:
###
###   F:\biocbuild\bbs-3.20-bioc\R\bin\R.exe CMD INSTALL ProteoDisco
###
##############################################################################
##############################################################################


* installing to library 'F:/biocbuild/bbs-3.20-bioc/R/library'
* installing *source* package 'ProteoDisco' ...
** using staged installation
** R
** data
** inst
** byte-compile and prepare package for lazy loading
Warning: replacing previous import 'dplyr::rename' by 'plyr::rename' when loading 'ProteoDisco'
Warning: replacing previous import 'dplyr::count' by 'plyr::count' when loading 'ProteoDisco'
Warning: replacing previous import 'dplyr::failwith' by 'plyr::failwith' when loading 'ProteoDisco'
Warning: replacing previous import 'dplyr::id' by 'plyr::id' when loading 'ProteoDisco'
Warning: replacing previous import 'dplyr::summarize' by 'plyr::summarize' when loading 'ProteoDisco'
Warning: replacing previous import 'dplyr::summarise' by 'plyr::summarise' when loading 'ProteoDisco'
Warning: replacing previous import 'dplyr::mutate' by 'plyr::mutate' when loading 'ProteoDisco'
Warning: replacing previous import 'dplyr::desc' by 'plyr::desc' when loading 'ProteoDisco'
Warning: replacing previous import 'dplyr::arrange' by 'plyr::arrange' when loading 'ProteoDisco'
** help
*** installing help indices
** building package indices
** installing vignettes
** testing if installed package can be loaded from temporary location
Warning: replacing previous import 'dplyr::rename' by 'plyr::rename' when loading 'ProteoDisco'
Warning: replacing previous import 'dplyr::count' by 'plyr::count' when loading 'ProteoDisco'
Warning: replacing previous import 'dplyr::failwith' by 'plyr::failwith' when loading 'ProteoDisco'
Warning: replacing previous import 'dplyr::id' by 'plyr::id' when loading 'ProteoDisco'
Warning: replacing previous import 'dplyr::summarize' by 'plyr::summarize' when loading 'ProteoDisco'
Warning: replacing previous import 'dplyr::summarise' by 'plyr::summarise' when loading 'ProteoDisco'
Warning: replacing previous import 'dplyr::mutate' by 'plyr::mutate' when loading 'ProteoDisco'
Warning: replacing previous import 'dplyr::desc' by 'plyr::desc' when loading 'ProteoDisco'
Warning: replacing previous import 'dplyr::arrange' by 'plyr::arrange' when loading 'ProteoDisco'
** testing if installed package can be loaded from final location
Warning: replacing previous import 'dplyr::rename' by 'plyr::rename' when loading 'ProteoDisco'
Warning: replacing previous import 'dplyr::count' by 'plyr::count' when loading 'ProteoDisco'
Warning: replacing previous import 'dplyr::failwith' by 'plyr::failwith' when loading 'ProteoDisco'
Warning: replacing previous import 'dplyr::id' by 'plyr::id' when loading 'ProteoDisco'
Warning: replacing previous import 'dplyr::summarize' by 'plyr::summarize' when loading 'ProteoDisco'
Warning: replacing previous import 'dplyr::summarise' by 'plyr::summarise' when loading 'ProteoDisco'
Warning: replacing previous import 'dplyr::mutate' by 'plyr::mutate' when loading 'ProteoDisco'
Warning: replacing previous import 'dplyr::desc' by 'plyr::desc' when loading 'ProteoDisco'
Warning: replacing previous import 'dplyr::arrange' by 'plyr::arrange' when loading 'ProteoDisco'
** testing if installed package keeps a record of temporary installation path
* DONE (ProteoDisco)

Tests output

ProteoDisco.Rcheck/tests/testthat.Rout


R version 4.4.2 (2024-10-31 ucrt) -- "Pile of Leaves"
Copyright (C) 2024 The R Foundation for Statistical Computing
Platform: x86_64-w64-mingw32/x64

R is free software and comes with ABSOLUTELY NO WARRANTY.
You are welcome to redistribute it under certain conditions.
Type 'license()' or 'licence()' for distribution details.

R is a collaborative project with many contributors.
Type 'contributors()' for more information and
'citation()' on how to cite R or R packages in publications.

Type 'demo()' for some demos, 'help()' for on-line help, or
'help.start()' for an HTML browser interface to help.
Type 'q()' to quit R.

> Sys.setenv("R_TESTS" = "")
> 
> library(testthat)
> library(ProteoDisco)
Warning messages:
1: replacing previous import 'dplyr::rename' by 'plyr::rename' when loading 'ProteoDisco' 
2: replacing previous import 'dplyr::count' by 'plyr::count' when loading 'ProteoDisco' 
3: replacing previous import 'dplyr::failwith' by 'plyr::failwith' when loading 'ProteoDisco' 
4: replacing previous import 'dplyr::id' by 'plyr::id' when loading 'ProteoDisco' 
5: replacing previous import 'dplyr::summarize' by 'plyr::summarize' when loading 'ProteoDisco' 
6: replacing previous import 'dplyr::summarise' by 'plyr::summarise' when loading 'ProteoDisco' 
7: replacing previous import 'dplyr::mutate' by 'plyr::mutate' when loading 'ProteoDisco' 
8: replacing previous import 'dplyr::desc' by 'plyr::desc' when loading 'ProteoDisco' 
9: replacing previous import 'dplyr::arrange' by 'plyr::arrange' when loading 'ProteoDisco' 
> 
> testthat::test_check("ProteoDisco")
ProteoDisco - Importing manual transcript sequences to the ProteoDiscography.
ProteoDisco - Importing splice-junctions to the ProteoDiscography.
ProteoDisco - Generating splice-junctions models based on 9 unique (sample-specific or aggregated) splice-junctions.
Retrieving all CDS-records from the TxDb.

  |                                                                            
  |                                                                      |   0%Retrieving overlapping or adjacent CDS for each splice-junction: testSJ
Retrieving 5'-adjacent or overlapping CDS.
Retrieving 3'-adjacent or overlapping CDS.

  |                                                                            
  |======================================================================| 100%

ProteoDisco - Ignoring subsetting on shared seqlevels as a BSgenome was given.
ProteoDisco - Generating the annotation database (ProteoDiscography)
ProteoDisco - Importing genomic variants from 1 file(s) to the ProteoDiscography.
ProteoDisco - Importing 1 VCF file(s).

  |                                                                            
  |                                                                      |   0%ProteoDisco - Importing F:/biocbuild/bbs-3.20-bioc/R/library/ProteoDisco/extdata/validationSet_hg19.vcf
ProteoDisco - Checking sanity of reference anchors for validationSet_hg19.vcf.
ProteoDisco - Checking sanity of reference anchors in chr1 (using 1 threads)
ProteoDisco - Checking sanity of reference anchors in chr2 (using 1 threads)
ProteoDisco - Checking sanity of reference anchors in chr3 (using 1 threads)
ProteoDisco - Checking sanity of reference anchors in chr6 (using 1 threads)
ProteoDisco - Checking sanity of reference anchors in chr7 (using 1 threads)
ProteoDisco - Checking sanity of reference anchors in chr10 (using 1 threads)
ProteoDisco - Checking sanity of reference anchors in chr11 (using 1 threads)
ProteoDisco - Checking sanity of reference anchors in chr13 (using 1 threads)
ProteoDisco - Checking sanity of reference anchors in chr14 (using 1 threads)
ProteoDisco - Checking sanity of reference anchors in chr17 (using 1 threads)
ProteoDisco - Checking sanity of reference anchors in chr19 (using 1 threads)
ProteoDisco - Checking sanity of reference anchors in chrX (using 1 threads)

  |                                                                            
  |======================================================================| 100%

	ProteoDisco - Calculating a prelim. overlap of genomic mutations with given annotations
ProteoDisco - Adding SNV/MNV and InDel mutations to transcript sequences.
	ProteoDisco - Finding overlap of mutations with CDS within the TxDb.
	ProteoDisco - Incorporating mutations within the CDS sequence(s).
		Working on sample: validationSet_hg19.vcf (28 overlapping CDS; 4 threads)

  |                                                                            
  |                                                                      |   0%			Working on CDS: 114412 (validationSet_hg19.vcf)

  |                                                                            
  |==                                                                    |   3%			Working on CDS: 126702 (validationSet_hg19.vcf)

  |                                                                            
  |====                                                                  |   6%			Working on CDS: 13114 (validationSet_hg19.vcf)

  |                                                                            
  |======                                                                |   9%			Working on CDS: 147351 (validationSet_hg19.vcf)

  |                                                                            
  |========                                                              |  12%			Working on CDS: 157704 (validationSet_hg19.vcf)

  |                                                                            
  |===========                                                           |  15%			Working on CDS: 157710 (validationSet_hg19.vcf)

  |                                                                            
  |=============                                                         |  18%			Working on CDS: 183308 (validationSet_hg19.vcf)

  |                                                                            
  |===============                                                       |  21%			Working on CDS: 183309 (validationSet_hg19.vcf)

  |                                                                            
  |=================                                                     |  24%			Working on CDS: 186841 (validationSet_hg19.vcf)

  |                                                                            
  |===================                                                   |  27%			Working on CDS: 197660 (validationSet_hg19.vcf)

  |                                                                            
  |=====================                                                 |  30%			Working on CDS: 197662 (validationSet_hg19.vcf)

  |                                                                            
  |=======================                                               |  33%			Working on CDS: 220567 (validationSet_hg19.vcf)

  |                                                                            
  |=========================                                             |  36%			Working on CDS: 25123 (validationSet_hg19.vcf)

  |                                                                            
  |============================                                          |  39%			Working on CDS: 25135 (validationSet_hg19.vcf)

  |                                                                            
  |==============================                                        |  42%			Working on CDS: 25146 (validationSet_hg19.vcf)

  |                                                                            
  |================================                                      |  45%			Working on CDS: 25149 (validationSet_hg19.vcf)

  |                                                                            
  |==================================                                    |  48%			Working on CDS: 38664 (validationSet_hg19.vcf)

  |                                                                            
  |====================================                                  |  52%			Working on CDS: 38670 (validationSet_hg19.vcf)

  |                                                                            
  |======================================                                |  55%			Working on CDS: 49583 (validationSet_hg19.vcf)

  |                                                                            
  |========================================                              |  58%			Working on CDS: 49584 (validationSet_hg19.vcf)

  |                                                                            
  |==========================================                            |  61%			Working on CDS: 73734 (validationSet_hg19.vcf)

  |                                                                            
  |=============================================                         |  64%			Working on CDS: 73737 (validationSet_hg19.vcf)

  |                                                                            
  |===============================================                       |  67%			Working on CDS: 77574 (validationSet_hg19.vcf)

  |                                                                            
  |=================================================                     |  70%			Working on CDS: 77575 (validationSet_hg19.vcf)

  |                                                                            
  |===================================================                   |  73%			Working on CDS: 77579 (validationSet_hg19.vcf)

  |                                                                            
  |=====================================================                 |  76%			Working on CDS: 77580 (validationSet_hg19.vcf)

  |                                                                            
  |=======================================================               |  79%			Working on CDS: 77581 (validationSet_hg19.vcf)

  |                                                                            
  |=========================================================             |  82%			Working on CDS: 84767 (validationSet_hg19.vcf)

  |                                                                            
  |===========================================================           |  85%			Working on CDS: 84768 (validationSet_hg19.vcf)

  |                                                                            
  |==============================================================        |  88%			Working on CDS: 84771 (validationSet_hg19.vcf)

  |                                                                            
  |================================================================      |  91%			Working on CDS: 84772 (validationSet_hg19.vcf)

  |                                                                            
  |==================================================================    |  94%			Working on CDS: 85674 (validationSet_hg19.vcf)

  |                                                                            
  |====================================================================  |  97%			Working on CDS: 85702 (validationSet_hg19.vcf)

  |                                                                            
  |======================================================================| 100%

	ProteoDisco - Generating mutant transcript sequence(s) by replacing wild-type to mutant CDS.
		Working on sample: validationSet_hg19.vcf (33 mutant CDS; 4 threads)

  |                                                                            
  |                                                                      |   0%		Working on TX: 12501 (validationSet_hg19.vcf)

  |                                                                            
  |=                                                                     |   1%		Working on TX: 12503 (validationSet_hg19.vcf)

  |                                                                            
  |==                                                                    |   3%		Working on TX: 12504 (validationSet_hg19.vcf)

  |                                                                            
  |===                                                                   |   4%		Working on TX: 16025 (validationSet_hg19.vcf)

  |                                                                            
  |====                                                                  |   6%		Working on TX: 24255 (validationSet_hg19.vcf)

  |                                                                            
  |=====                                                                 |   7%		Working on TX: 25556 (validationSet_hg19.vcf)

  |                                                                            
  |======                                                                |   9%		Working on TX: 25557 (validationSet_hg19.vcf)

  |                                                                            
  |=======                                                               |  10%		Working on TX: 25558 (validationSet_hg19.vcf)

  |                                                                            
  |========                                                              |  11%		Working on TX: 25559 (validationSet_hg19.vcf)

  |                                                                            
  |=========                                                             |  13%		Working on TX: 25560 (validationSet_hg19.vcf)

  |                                                                            
  |==========                                                            |  14%		Working on TX: 25561 (validationSet_hg19.vcf)

  |                                                                            
  |===========                                                           |  16%		Working on TX: 25562 (validationSet_hg19.vcf)

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  |============                                                          |  17%		Working on TX: 25563 (validationSet_hg19.vcf)

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  |=============                                                         |  19%		Working on TX: 25565 (validationSet_hg19.vcf)

  |                                                                            
  |==============                                                        |  20%		Working on TX: 25568 (validationSet_hg19.vcf)

  |                                                                            
  |===============                                                       |  21%		Working on TX: 25569 (validationSet_hg19.vcf)

  |                                                                            
  |================                                                      |  23%		Working on TX: 25570 (validationSet_hg19.vcf)

  |                                                                            
  |=================                                                     |  24%		Working on TX: 25571 (validationSet_hg19.vcf)

  |                                                                            
  |==================                                                    |  26%		Working on TX: 25572 (validationSet_hg19.vcf)

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  |===================                                                   |  27%		Working on TX: 25573 (validationSet_hg19.vcf)

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  |====================                                                  |  29%		Working on TX: 28087 (validationSet_hg19.vcf)

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  |=====================                                                 |  30%		Working on TX: 28088 (validationSet_hg19.vcf)

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  |======================                                                |  31%		Working on TX: 28089 (validationSet_hg19.vcf)

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  |=======================                                               |  33%		Working on TX: 28090 (validationSet_hg19.vcf)

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  |========================                                              |  34%		Working on TX: 28435 (validationSet_hg19.vcf)

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  |=========================                                             |  36%		Working on TX: 28436 (validationSet_hg19.vcf)

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  |==========================                                            |  37%		Working on TX: 28437 (validationSet_hg19.vcf)

  |                                                                            
  |===========================                                           |  39%		Working on TX: 28438 (validationSet_hg19.vcf)

  |                                                                            
  |============================                                          |  40%		Working on TX: 28439 (validationSet_hg19.vcf)

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  |================================                                      |  46%		Working on TX: 38563 (validationSet_hg19.vcf)

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  |=================================                                     |  47%		Working on TX: 42727 (validationSet_hg19.vcf)

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  |==================================                                    |  49%		Working on TX: 42728 (validationSet_hg19.vcf)

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  |==========================================================            |  83%		Working on TX: 63856 (validationSet_hg19.vcf)

  |                                                                            
  |===========================================================           |  84%		Working on TX: 67278 (validationSet_hg19.vcf)

  |                                                                            
  |============================================================          |  86%		Working on TX: 76042 (validationSet_hg19.vcf)

  |                                                                            
  |=============================================================         |  87%		Working on TX: 76044 (validationSet_hg19.vcf)

  |                                                                            
  |==============================================================        |  89%		Working on TX: 8423 (validationSet_hg19.vcf)

  |                                                                            
  |===============================================================       |  90%		Working on TX: 8424 (validationSet_hg19.vcf)

  |                                                                            
  |================================================================      |  91%		Working on TX: 8425 (validationSet_hg19.vcf)

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  |=================================================================     |  93%		Working on TX: 8426 (validationSet_hg19.vcf)

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  |==================================================================    |  94%		Working on TX: 8427 (validationSet_hg19.vcf)

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  |===================================================================   |  96%		Working on TX: 8431 (validationSet_hg19.vcf)

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  |====================================================================  |  97%		Working on TX: 8432 (validationSet_hg19.vcf)

  |                                                                            
  |===================================================================== |  99%		Working on TX: 8433 (validationSet_hg19.vcf)

  |                                                                            
  |======================================================================| 100%

Retrieving 3' UTR
	ProteoDisco - Adding mutant transcripts to the ProteoDiscography.
ProteoDisco - Adding SNV/MNV and InDel mutations to transcript sequences.
	ProteoDisco - Finding overlap of mutations with CDS within the TxDb.
	ProteoDisco - Incorporating mutations within the CDS sequence(s).
		Working on sample: validationSet_hg19.vcf (28 overlapping CDS; 4 threads)

  |                                                                            
  |                                                                      |   0%			Working on CDS: 114412 (validationSet_hg19.vcf)

  |                                                                            
  |==                                                                    |   3%			Working on CDS: 126702 (validationSet_hg19.vcf)

  |                                                                            
  |====                                                                  |   6%			Working on CDS: 13114 (validationSet_hg19.vcf)

  |                                                                            
  |======                                                                |   9%			Working on CDS: 147351 (validationSet_hg19.vcf)

  |                                                                            
  |========                                                              |  12%			Working on CDS: 157704 (validationSet_hg19.vcf)

  |                                                                            
  |===========                                                           |  15%			Working on CDS: 157710 (validationSet_hg19.vcf)

  |                                                                            
  |=============                                                         |  18%			Working on CDS: 183308 (validationSet_hg19.vcf)

  |                                                                            
  |===============                                                       |  21%			Working on CDS: 183309 (validationSet_hg19.vcf)

  |                                                                            
  |=================                                                     |  24%			Working on CDS: 186841 (validationSet_hg19.vcf)

  |                                                                            
  |===================                                                   |  27%			Working on CDS: 197660 (validationSet_hg19.vcf)

  |                                                                            
  |=====================                                                 |  30%			Working on CDS: 197662 (validationSet_hg19.vcf)

  |                                                                            
  |=======================                                               |  33%			Working on CDS: 220567 (validationSet_hg19.vcf)

  |                                                                            
  |=========================                                             |  36%			Working on CDS: 25123 (validationSet_hg19.vcf)

  |                                                                            
  |============================                                          |  39%			Working on CDS: 25135 (validationSet_hg19.vcf)

  |                                                                            
  |==============================                                        |  42%			Working on CDS: 25146 (validationSet_hg19.vcf)

  |                                                                            
  |================================                                      |  45%			Working on CDS: 25149 (validationSet_hg19.vcf)

  |                                                                            
  |==================================                                    |  48%			Working on CDS: 38664 (validationSet_hg19.vcf)

  |                                                                            
  |====================================                                  |  52%			Working on CDS: 38670 (validationSet_hg19.vcf)

  |                                                                            
  |======================================                                |  55%			Working on CDS: 49583 (validationSet_hg19.vcf)

  |                                                                            
  |========================================                              |  58%			Working on CDS: 49584 (validationSet_hg19.vcf)

  |                                                                            
  |==========================================                            |  61%			Working on CDS: 73734 (validationSet_hg19.vcf)

  |                                                                            
  |=============================================                         |  64%			Working on CDS: 73737 (validationSet_hg19.vcf)

  |                                                                            
  |===============================================                       |  67%			Working on CDS: 77574 (validationSet_hg19.vcf)

  |                                                                            
  |=================================================                     |  70%			Working on CDS: 77575 (validationSet_hg19.vcf)

  |                                                                            
  |===================================================                   |  73%			Working on CDS: 77579 (validationSet_hg19.vcf)

  |                                                                            
  |=====================================================                 |  76%			Working on CDS: 77580 (validationSet_hg19.vcf)

  |                                                                            
  |=======================================================               |  79%			Working on CDS: 77581 (validationSet_hg19.vcf)

  |                                                                            
  |=========================================================             |  82%			Working on CDS: 84767 (validationSet_hg19.vcf)

  |                                                                            
  |===========================================================           |  85%			Working on CDS: 84768 (validationSet_hg19.vcf)

  |                                                                            
  |==============================================================        |  88%			Working on CDS: 84771 (validationSet_hg19.vcf)

  |                                                                            
  |================================================================      |  91%			Working on CDS: 84772 (validationSet_hg19.vcf)

  |                                                                            
  |==================================================================    |  94%			Working on CDS: 85674 (validationSet_hg19.vcf)

  |                                                                            
  |====================================================================  |  97%			Working on CDS: 85702 (validationSet_hg19.vcf)

  |                                                                            
  |======================================================================| 100%

	ProteoDisco - Generating mutant transcript sequence(s) by replacing wild-type to mutant CDS.
		Working on sample: validationSet_hg19.vcf (34 mutant CDS; 4 threads)

  |                                                                            
  |                                                                      |   0%		Working on TX: 12501 (validationSet_hg19.vcf)

  |                                                                            
  |=                                                                     |   1%		Working on TX: 12503 (validationSet_hg19.vcf)

  |                                                                            
  |==                                                                    |   3%		Working on TX: 12504 (validationSet_hg19.vcf)

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  |===                                                                   |   4%		Working on TX: 16025 (validationSet_hg19.vcf)

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  |====                                                                  |   6%		Working on TX: 24255 (validationSet_hg19.vcf)

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  |=====                                                                 |   7%		Working on TX: 25556 (validationSet_hg19.vcf)

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  |======                                                                |   9%		Working on TX: 25557 (validationSet_hg19.vcf)

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  |=======                                                               |  10%		Working on TX: 25558 (validationSet_hg19.vcf)

  |                                                                            
  |========                                                              |  11%		Working on TX: 25559 (validationSet_hg19.vcf)

  |                                                                            
  |=========                                                             |  13%		Working on TX: 25560 (validationSet_hg19.vcf)

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  |==========                                                            |  14%		Working on TX: 25561 (validationSet_hg19.vcf)

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  |===========                                                           |  16%		Working on TX: 25562 (validationSet_hg19.vcf)

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  |============                                                          |  17%		Working on TX: 25563 (validationSet_hg19.vcf)

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  |=============                                                         |  19%		Working on TX: 25565 (validationSet_hg19.vcf)

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  |===============                                                       |  21%		Working on TX: 25569 (validationSet_hg19.vcf)

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  |================                                                      |  23%		Working on TX: 25570 (validationSet_hg19.vcf)

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  |=================                                                     |  24%		Working on TX: 25571 (validationSet_hg19.vcf)

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  |==========================                                            |  37%		Working on TX: 28437 (validationSet_hg19.vcf)

  |                                                                            
  |===========================                                           |  39%		Working on TX: 28438 (validationSet_hg19.vcf)

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  |=================================                                     |  47%		Working on TX: 42727 (validationSet_hg19.vcf)

  |                                                                            
  |==================================                                    |  49%		Working on TX: 42728 (validationSet_hg19.vcf)

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  |================================================                      |  69%		Working on TX: 62644 (validationSet_hg19.vcf)

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  |==================================================                    |  71%		Working on TX: 62648 (validationSet_hg19.vcf)

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  |                                                                            
  |=========================================================             |  81%		Working on TX: 63855 (validationSet_hg19.vcf)

  |                                                                            
  |==========================================================            |  83%		Working on TX: 63856 (validationSet_hg19.vcf)

  |                                                                            
  |===========================================================           |  84%		Working on TX: 67278 (validationSet_hg19.vcf)

  |                                                                            
  |============================================================          |  86%		Working on TX: 76042 (validationSet_hg19.vcf)

  |                                                                            
  |=============================================================         |  87%		Working on TX: 76044 (validationSet_hg19.vcf)

  |                                                                            
  |==============================================================        |  89%		Working on TX: 8423 (validationSet_hg19.vcf)

  |                                                                            
  |===============================================================       |  90%		Working on TX: 8424 (validationSet_hg19.vcf)

  |                                                                            
  |================================================================      |  91%		Working on TX: 8425 (validationSet_hg19.vcf)

  |                                                                            
  |=================================================================     |  93%		Working on TX: 8426 (validationSet_hg19.vcf)

  |                                                                            
  |==================================================================    |  94%		Working on TX: 8427 (validationSet_hg19.vcf)

  |                                                                            
  |===================================================================   |  96%		Working on TX: 8431 (validationSet_hg19.vcf)

  |                                                                            
  |====================================================================  |  97%		Working on TX: 8432 (validationSet_hg19.vcf)

  |                                                                            
  |===================================================================== |  99%		Working on TX: 8433 (validationSet_hg19.vcf)

  |                                                                            
  |======================================================================| 100%

Retrieving 3' UTR
	ProteoDisco - Adding mutant transcripts to the ProteoDiscography.
ProteoDisco - Exporting mutant protein isoforms.
	Exporting 99 mutant protein sequences.
	Writing to test.FASTA.
[ FAIL 0 | WARN 8 | SKIP 0 | PASS 11 ]

[ FAIL 0 | WARN 8 | SKIP 0 | PASS 11 ]
> 
> proc.time()
   user  system elapsed 
 231.48    7.00  261.42 

Example timings

ProteoDisco.Rcheck/ProteoDisco-Ex.timings

nameusersystemelapsed
checkProteotypicFragments0.500.200.78
exportProteoDiscography0.380.250.64
generateJunctionModels15.03 0.7839.73
generateProteoDiscography000
getDiscography0.310.200.52
importGenomicVariants.MAF4.370.194.56
importGenomicVariants3.830.023.84
importGenomicVariants.VCF3.860.063.92
importSpliceJunctions0.340.090.44
importTranscriptSequences0.250.000.25
incorporateGenomicVariants41.00 1.2542.25
mutantTranscripts0.360.230.60
setGenomicSequences0.330.190.51
setMutantTranscripts0.480.190.68
setTxDb0.380.250.62