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This page was generated on 2025-10-13 11:41 -0400 (Mon, 13 Oct 2025).

HostnameOSArch (*)R versionInstalled pkgs
nebbiolo1Linux (Ubuntu 24.04.3 LTS)x86_644.5.1 (2025-06-13) -- "Great Square Root" 4833
merida1macOS 12.7.5 Montereyx86_644.5.1 RC (2025-06-05 r88288) -- "Great Square Root" 4614
kjohnson1macOS 13.6.6 Venturaarm644.5.1 Patched (2025-06-14 r88325) -- "Great Square Root" 4555
kunpeng2Linux (openEuler 24.03 LTS)aarch64R Under development (unstable) (2025-02-19 r87757) -- "Unsuffered Consequences" 4586
Click on any hostname to see more info about the system (e.g. compilers)      (*) as reported by 'uname -p', except on Windows and Mac OS X

Package 163/2341HostnameOS / ArchINSTALLBUILDCHECKBUILD BIN
BERT 1.4.0  (landing page)
Yannis Schumann
Snapshot Date: 2025-10-09 13:40 -0400 (Thu, 09 Oct 2025)
git_url: https://git.bioconductor.org/packages/BERT
git_branch: RELEASE_3_21
git_last_commit: dedce04
git_last_commit_date: 2025-04-15 13:25:40 -0400 (Tue, 15 Apr 2025)
nebbiolo1Linux (Ubuntu 24.04.3 LTS) / x86_64  OK    OK    OK  UNNEEDED, same version is already published
merida1macOS 12.7.5 Monterey / x86_64  OK    OK    OK    OK  UNNEEDED, same version is already published
kjohnson1macOS 13.6.6 Ventura / arm64  OK    OK    OK    OK  UNNEEDED, same version is already published
kunpeng2Linux (openEuler 24.03 LTS) / aarch64  OK    OK    OK  


CHECK results for BERT on kunpeng2

To the developers/maintainers of the BERT package:
- Allow up to 24 hours (and sometimes 48 hours) for your latest push to git@git.bioconductor.org:packages/BERT.git to reflect on this report. See Troubleshooting Build Report for more information.
- Use the following Renviron settings to reproduce errors and warnings.
- If 'R CMD check' started to fail recently on the Linux builder(s) over a missing dependency, add the missing dependency to 'Suggests:' in your DESCRIPTION file. See Renviron.bioc for more information.
- See Martin Grigorov's blog post for how to debug Linux ARM64 related issues on a x86_64 host.

raw results


Summary

Package: BERT
Version: 1.4.0
Command: /home/biocbuild/R/R/bin/R CMD check --install=check:BERT.install-out.txt --library=/home/biocbuild/R/R/site-library --no-vignettes --timings BERT_1.4.0.tar.gz
StartedAt: 2025-10-10 06:28:45 -0000 (Fri, 10 Oct 2025)
EndedAt: 2025-10-10 06:30:14 -0000 (Fri, 10 Oct 2025)
EllapsedTime: 89.1 seconds
RetCode: 0
Status:   OK  
CheckDir: BERT.Rcheck
Warnings: 0

Command output

##############################################################################
##############################################################################
###
### Running command:
###
###   /home/biocbuild/R/R/bin/R CMD check --install=check:BERT.install-out.txt --library=/home/biocbuild/R/R/site-library --no-vignettes --timings BERT_1.4.0.tar.gz
###
##############################################################################
##############################################################################


* using log directory ‘/home/biocbuild/bbs-3.21-bioc/meat/BERT.Rcheck’
* using R Under development (unstable) (2025-02-19 r87757)
* using platform: aarch64-unknown-linux-gnu
* R was compiled by
    aarch64-unknown-linux-gnu-gcc (GCC) 14.2.0
    GNU Fortran (GCC) 14.2.0
* running under: openEuler 24.03 (LTS-SP1)
* using session charset: UTF-8
* using option ‘--no-vignettes’
* checking for file ‘BERT/DESCRIPTION’ ... OK
* this is package ‘BERT’ version ‘1.4.0’
* package encoding: UTF-8
* checking package namespace information ... OK
* checking package dependencies ... OK
* checking if this is a source package ... OK
* checking if there is a namespace ... OK
* checking for hidden files and directories ... OK
* checking for portable file names ... OK
* checking for sufficient/correct file permissions ... OK
* checking whether package ‘BERT’ can be installed ... OK
* checking installed package size ... OK
* checking package directory ... OK
* checking ‘build’ directory ... OK
* checking DESCRIPTION meta-information ... OK
* checking top-level files ... OK
* checking for left-over files ... OK
* checking index information ... OK
* checking package subdirectories ... OK
* checking code files for non-ASCII characters ... OK
* checking R files for syntax errors ... OK
* checking whether the package can be loaded ... OK
* checking whether the package can be loaded with stated dependencies ... OK
* checking whether the package can be unloaded cleanly ... OK
* checking whether the namespace can be loaded with stated dependencies ... OK
* checking whether the namespace can be unloaded cleanly ... OK
* checking loading without being on the library search path ... OK
* checking dependencies in R code ... OK
* checking S3 generic/method consistency ... OK
* checking replacement functions ... OK
* checking foreign function calls ... OK
* checking R code for possible problems ... OK
* checking Rd files ... OK
* checking Rd metadata ... OK
* checking Rd cross-references ... OK
* checking for missing documentation entries ... OK
* checking for code/documentation mismatches ... OK
* checking Rd \usage sections ... OK
* checking Rd contents ... OK
* checking for unstated dependencies in examples ... OK
* checking files in ‘vignettes’ ... OK
* checking examples ... OK
Examples with CPU (user + system) or elapsed time > 5s
       user system elapsed
BERT 32.143  1.931  24.102
* checking for unstated dependencies in ‘tests’ ... OK
* checking tests ...
  Running ‘testthat.R’
 OK
* checking for unstated dependencies in vignettes ... OK
* checking package vignettes ... OK
* checking running R code from vignettes ... SKIPPED
* checking re-building of vignette outputs ... SKIPPED
* checking PDF version of manual ... OK
* DONE

Status: OK


Installation output

BERT.Rcheck/00install.out

##############################################################################
##############################################################################
###
### Running command:
###
###   /home/biocbuild/R/R/bin/R CMD INSTALL BERT
###
##############################################################################
##############################################################################


* installing to library ‘/home/biocbuild/R/R-devel_2025-02-19/site-library’
* installing *source* package ‘BERT’ ...
** this is package ‘BERT’ version ‘1.4.0’
** using staged installation
** R
** inst
** byte-compile and prepare package for lazy loading
** help
*** installing help indices
** building package indices
** installing vignettes
** testing if installed package can be loaded from temporary location
** testing if installed package can be loaded from final location
** testing if installed package keeps a record of temporary installation path
* DONE (BERT)

Tests output

BERT.Rcheck/tests/testthat.Rout


R Under development (unstable) (2025-02-19 r87757) -- "Unsuffered Consequences"
Copyright (C) 2025 The R Foundation for Statistical Computing
Platform: aarch64-unknown-linux-gnu

R is free software and comes with ABSOLUTELY NO WARRANTY.
You are welcome to redistribute it under certain conditions.
Type 'license()' or 'licence()' for distribution details.

R is a collaborative project with many contributors.
Type 'contributors()' for more information and
'citation()' on how to cite R or R packages in publications.

Type 'demo()' for some demos, 'help()' for on-line help, or
'help.start()' for an HTML browser interface to help.
Type 'q()' to quit R.

> # This file is part of the standard setup for testthat.
> # It is recommended that you do not modify it.
> #
> # Where should you do additional test configuration?
> # Learn more about the roles of various files in:
> # * https://r-pkgs.org/tests.html
> # * https://testthat.r-lib.org/reference/test_package.html#special-files
> 
> library(testthat)
> library(BERT)
> 
> test_check("BERT")
2025-10-10 06:29:57.337423 INFO::Formatting Data.
2025-10-10 06:29:57.339484 INFO::Replacing NaNs with NAs.
2025-10-10 06:29:57.358778 INFO::Removing potential empty rows and columns
2025-10-10 06:29:57.997148 INFO::Found  0  missing values.
2025-10-10 06:29:58.002088 INFO::Introduced 0 missing values due to singular proteins at batch/covariate level.
2025-10-10 06:29:58.00303 INFO::Done
2025-10-10 06:29:58.003823 INFO::Acquiring quality metrics before batch effect correction.
2025-10-10 06:29:58.020014 INFO::Starting hierarchical adjustment
2025-10-10 06:29:58.021323 INFO::Found  3  batches.
2025-10-10 06:29:58.022215 INFO::Cores argument is not defined or BPPARAM has been specified. Argument corereduction will not be used.
2025-10-10 06:29:58.023812 INFO::Using default BPPARAM
2025-10-10 06:29:58.024715 INFO::Processing subtree level 1
2025-10-10 06:29:58.183369 INFO::Adjusting the last 1 batches sequentially
2025-10-10 06:29:58.189559 INFO::Done
2025-10-10 06:29:58.190612 INFO::Acquiring quality metrics after batch effect correction.
2025-10-10 06:29:58.194404 INFO::ASW Batch was -0.0836556304129964 prior to batch effect correction and is now -0.0836556304129964 .
2025-10-10 06:29:58.196118 INFO::Total function execution time is  0.859652757644653  s and adjustment time is  0.168470621109009 s ( 19.6 )
2025-10-10 06:29:58.228923 INFO::Formatting Data.
2025-10-10 06:29:58.230257 INFO::Replacing NaNs with NAs.
2025-10-10 06:29:58.231721 INFO::Removing potential empty rows and columns
2025-10-10 06:29:58.233697 INFO::Found  0  missing values.
2025-10-10 06:29:58.235136 INFO::BERT requires at least 2 numeric values per batch/covariate level. This may reduce the number of adjustable features considerably, depending on the quantification technique.
2025-10-10 06:29:58.252246 INFO::Formatting Data.
2025-10-10 06:29:58.253323 INFO::Replacing NaNs with NAs.
2025-10-10 06:29:58.254627 INFO::Removing potential empty rows and columns
2025-10-10 06:29:58.256146 INFO::Found  0  missing values.
2025-10-10 06:29:58.257525 INFO::BERT requires at least 2 numeric values per batch/covariate level. This may reduce the number of adjustable features considerably, depending on the quantification technique.
2025-10-10 06:29:58.282014 INFO::Formatting Data.
2025-10-10 06:29:58.283188 INFO::Replacing NaNs with NAs.
2025-10-10 06:29:58.284665 INFO::Removing potential empty rows and columns
2025-10-10 06:29:58.28634 INFO::Found  0  missing values.
2025-10-10 06:29:58.287798 INFO::BERT requires at least 2 numeric values per batch/covariate level. This may reduce the number of adjustable features considerably, depending on the quantification technique.
2025-10-10 06:29:58.294978 INFO::Introduced 0 missing values due to singular proteins at batch/covariate level.
2025-10-10 06:29:58.29598 INFO::Done
2025-10-10 06:29:58.296848 INFO::Acquiring quality metrics before batch effect correction.
2025-10-10 06:29:58.300204 INFO::Starting hierarchical adjustment
2025-10-10 06:29:58.301449 INFO::Found  2  batches.
2025-10-10 06:29:58.302251 INFO::Cores argument is not defined or BPPARAM has been specified. Argument corereduction will not be used.
2025-10-10 06:29:58.303244 INFO::Using default BPPARAM
2025-10-10 06:29:58.304037 INFO::Adjusting the last 2 batches sequentially
2025-10-10 06:29:58.30547 INFO::Adjusting sequential tree level 1 with 2 batches
2025-10-10 06:29:58.340941 INFO::Done
2025-10-10 06:29:58.341929 INFO::Acquiring quality metrics after batch effect correction.
2025-10-10 06:29:58.344923 INFO::ASW Batch was 0.0367147070447992 prior to batch effect correction and is now -0.109881239999698 .
2025-10-10 06:29:58.346184 INFO::Total function execution time is  0.0642273426055908  s and adjustment time is  0.0396983623504639 s ( 61.81 )
2025-10-10 06:29:58.350254 INFO::Formatting Data.
2025-10-10 06:29:58.35132 INFO::Replacing NaNs with NAs.
2025-10-10 06:29:58.364304 INFO::Formatting Data.
2025-10-10 06:29:58.365362 INFO::Replacing NaNs with NAs.
2025-10-10 06:29:58.366614 INFO::Removing potential empty rows and columns
2025-10-10 06:29:58.368173 INFO::Found  0  missing values.
2025-10-10 06:29:58.418781 INFO::Introduced 0 missing values due to singular proteins at batch/covariate level.
2025-10-10 06:29:58.420165 INFO::Done
2025-10-10 06:29:58.420991 INFO::Acquiring quality metrics before batch effect correction.
2025-10-10 06:29:58.423974 INFO::Starting hierarchical adjustment
2025-10-10 06:29:58.425146 INFO::Found  2  batches.
2025-10-10 06:29:58.425986 INFO::Cores argument is not defined or BPPARAM has been specified. Argument corereduction will not be used.
2025-10-10 06:29:58.426871 INFO::Using default BPPARAM
2025-10-10 06:29:58.427635 INFO::Adjusting the last 2 batches sequentially
2025-10-10 06:29:58.42902 INFO::Adjusting sequential tree level 1 with 2 batches
design matrix of interest not specified. Assuming a one-group experiment.
2025-10-10 06:29:58.451186 INFO::Done
2025-10-10 06:29:58.45219 INFO::Acquiring quality metrics after batch effect correction.
2025-10-10 06:29:58.455357 INFO::ASW Batch was -0.0551571235222035 prior to batch effect correction and is now -0.103718583026259 .
2025-10-10 06:29:58.456622 INFO::Total function execution time is  0.0923209190368652  s and adjustment time is  0.0262446403503418 s ( 28.43 )
2025-10-10 06:29:58.45827 INFO::Formatting Data.
2025-10-10 06:29:58.459183 INFO::Replacing NaNs with NAs.
2025-10-10 06:29:58.4605 INFO::Removing potential empty rows and columns
2025-10-10 06:29:58.462212 INFO::Found  0  missing values.
2025-10-10 06:29:58.46695 INFO::Introduced 0 missing values due to singular proteins at batch/covariate level.
2025-10-10 06:29:58.467956 INFO::Done
2025-10-10 06:29:58.468894 INFO::Acquiring quality metrics before batch effect correction.
2025-10-10 06:29:58.472119 INFO::Starting hierarchical adjustment
2025-10-10 06:29:58.47339 INFO::Found  2  batches.
2025-10-10 06:29:58.474308 INFO::Cores argument is not defined or BPPARAM has been specified. Argument corereduction will not be used.
2025-10-10 06:29:58.475312 INFO::Using default BPPARAM
2025-10-10 06:29:58.47618 INFO::Adjusting the last 2 batches sequentially
2025-10-10 06:29:58.477702 INFO::Adjusting sequential tree level 1 with 2 batches
design matrix of interest not specified. Assuming a one-group experiment.
2025-10-10 06:29:58.500498 INFO::Done
2025-10-10 06:29:58.501468 INFO::Acquiring quality metrics after batch effect correction.
2025-10-10 06:29:58.504501 INFO::ASW Batch was -0.0551571235222035 prior to batch effect correction and is now -0.103718583026259 .
2025-10-10 06:29:58.505869 INFO::Total function execution time is  0.0475413799285889  s and adjustment time is  0.027338981628418 s ( 57.51 )
2025-10-10 06:30:02.818025 INFO::Formatting Data.
2025-10-10 06:30:02.818958 INFO::Recognized SummarizedExperiment
2025-10-10 06:30:02.81963 INFO::Typecasting input to dataframe.
2025-10-10 06:30:02.86057 INFO::Replacing NaNs with NAs.
2025-10-10 06:30:02.862076 INFO::Removing potential empty rows and columns
2025-10-10 06:30:02.86732 INFO::Found  0  missing values.
2025-10-10 06:30:02.877536 INFO::Introduced 0 missing values due to singular proteins at batch/covariate level.
2025-10-10 06:30:02.87846 INFO::Done
2025-10-10 06:30:02.879213 INFO::Acquiring quality metrics before batch effect correction.
2025-10-10 06:30:02.88444 INFO::Starting hierarchical adjustment
2025-10-10 06:30:02.885576 INFO::Found  2  batches.
2025-10-10 06:30:02.886354 INFO::Cores argument is not defined or BPPARAM has been specified. Argument corereduction will not be used.
2025-10-10 06:30:02.887728 INFO::Using default BPPARAM
2025-10-10 06:30:02.888462 INFO::Adjusting the last 2 batches sequentially
2025-10-10 06:30:02.889845 INFO::Adjusting sequential tree level 1 with 2 batches
2025-10-10 06:30:02.967371 INFO::Done
2025-10-10 06:30:02.968239 INFO::Acquiring quality metrics after batch effect correction.
2025-10-10 06:30:02.972996 INFO::ASW Batch was 0.00139120191503051 prior to batch effect correction and is now -0.0959514328348643 .
2025-10-10 06:30:02.974182 INFO::Total function execution time is  0.156574726104736  s and adjustment time is  0.0820069313049316 s ( 52.38 )
2025-10-10 06:30:02.997907 INFO::Formatting Data.
2025-10-10 06:30:02.998827 INFO::Recognized SummarizedExperiment
2025-10-10 06:30:02.999547 INFO::Typecasting input to dataframe.
2025-10-10 06:30:03.012156 INFO::Replacing NaNs with NAs.
2025-10-10 06:30:03.01376 INFO::Removing potential empty rows and columns
2025-10-10 06:30:03.018845 INFO::Found  0  missing values.
2025-10-10 06:30:03.02905 INFO::Introduced 0 missing values due to singular proteins at batch/covariate level.
2025-10-10 06:30:03.029961 INFO::Done
2025-10-10 06:30:03.030716 INFO::Acquiring quality metrics before batch effect correction.
2025-10-10 06:30:03.035555 INFO::Starting hierarchical adjustment
2025-10-10 06:30:03.03671 INFO::Found  2  batches.
2025-10-10 06:30:03.037454 INFO::Cores argument is not defined or BPPARAM has been specified. Argument corereduction will not be used.
2025-10-10 06:30:03.038291 INFO::Using default BPPARAM
2025-10-10 06:30:03.039006 INFO::Adjusting the last 2 batches sequentially
2025-10-10 06:30:03.040318 INFO::Adjusting sequential tree level 1 with 2 batches
2025-10-10 06:30:03.075282 INFO::Done
2025-10-10 06:30:03.076168 INFO::Acquiring quality metrics after batch effect correction.
2025-10-10 06:30:03.080997 INFO::ASW Batch was -0.00716929382694718 prior to batch effect correction and is now -0.00716929382694718 .
2025-10-10 06:30:03.08223 INFO::Total function execution time is  0.0842800140380859  s and adjustment time is  0.0387985706329346 s ( 46.04 )
2025-10-10 06:30:03.118778 INFO::Formatting Data.
2025-10-10 06:30:03.119882 INFO::Replacing NaNs with NAs.
2025-10-10 06:30:03.121176 INFO::Removing potential empty rows and columns
2025-10-10 06:30:03.122669 INFO::Found  0  missing values.
2025-10-10 06:30:03.126915 INFO::Introduced 0 missing values due to singular proteins at batch/covariate level.
2025-10-10 06:30:03.127789 INFO::Done
2025-10-10 06:30:03.12851 INFO::Acquiring quality metrics before batch effect correction.
2025-10-10 06:30:03.131516 INFO::Starting hierarchical adjustment
2025-10-10 06:30:03.132597 INFO::Found  3  batches.
2025-10-10 06:30:03.133358 INFO::Cores argument is not defined or BPPARAM has been specified. Argument corereduction will not be used.
2025-10-10 06:30:03.134263 INFO::Using default BPPARAM
2025-10-10 06:30:03.134991 INFO::Processing subtree level 1
2025-10-10 06:30:03.574219 INFO::Adjusting the last 1 batches sequentially
2025-10-10 06:30:03.576466 INFO::Done
2025-10-10 06:30:03.581542 INFO::Acquiring quality metrics after batch effect correction.
2025-10-10 06:30:03.589046 INFO::ASW Batch was 0.0233235848832988 prior to batch effect correction and is now -0.123490291791347 .
2025-10-10 06:30:03.590475 INFO::Total function execution time is  0.471816301345825  s and adjustment time is  0.444135427474976 s ( 94.13 )
2025-10-10 06:30:03.689966 INFO::Skipping initial DF formatting
2025-10-10 06:30:03.690939 INFO::Acquiring quality metrics before batch effect correction.
2025-10-10 06:30:03.696705 INFO::Starting hierarchical adjustment
2025-10-10 06:30:03.697895 INFO::Found  5  batches.
2025-10-10 06:30:03.698703 INFO::Cores argument is not defined or BPPARAM has been specified. Argument corereduction will not be used.
2025-10-10 06:30:03.699598 INFO::Using default BPPARAM
2025-10-10 06:30:03.700356 INFO::Processing subtree level 1
2025-10-10 06:30:03.920239 INFO::Adjusting the last 2 batches sequentially
2025-10-10 06:30:03.922713 INFO::Adjusting sequential tree level 1 with 2 batches
2025-10-10 06:30:03.958405 INFO::Done
2025-10-10 06:30:03.959388 INFO::Acquiring quality metrics after batch effect correction.
2025-10-10 06:30:03.966038 INFO::ASW Batch was 0.501565233141869 prior to batch effect correction and is now 0.501565233141869 .
2025-10-10 06:30:03.967005 INFO::ASW Label was 0.36280972653471 prior to batch effect correction and is now 0.36280972653471 .
2025-10-10 06:30:03.968284 INFO::Total function execution time is  0.278382062911987  s and adjustment time is  0.260743618011475 s ( 93.66 )
2025-10-10 06:30:03.996861 INFO::Formatting Data.
2025-10-10 06:30:03.997997 INFO::Replacing NaNs with NAs.
2025-10-10 06:30:03.999329 INFO::Removing potential empty rows and columns
2025-10-10 06:30:04.000919 INFO::Found  0  missing values.
2025-10-10 06:30:04.007674 INFO::Introduced 0 missing values due to singular proteins at batch/covariate level.
2025-10-10 06:30:04.008667 INFO::Done
2025-10-10 06:30:04.009511 INFO::Acquiring quality metrics before batch effect correction.
2025-10-10 06:30:04.014241 INFO::Starting hierarchical adjustment
2025-10-10 06:30:04.015408 INFO::Found  5  batches.
2025-10-10 06:30:04.016249 INFO::Cores argument is not defined or BPPARAM has been specified. Argument corereduction will not be used.
2025-10-10 06:30:04.017256 INFO::Using default BPPARAM
2025-10-10 06:30:04.018101 INFO::Processing subtree level 1
design matrix of interest not specified. Assuming a one-group experiment.

design matrix of interest not specified. Assuming a one-group experiment.
design matrix of interest not specified. Assuming a one-group experiment.

2025-10-10 06:30:04.178579 INFO::Adjusting the last 2 batches sequentially
2025-10-10 06:30:04.180938 INFO::Adjusting sequential tree level 1 with 2 batches
design matrix of interest not specified. Assuming a one-group experiment.
2025-10-10 06:30:04.206815 INFO::Done
2025-10-10 06:30:04.207818 INFO::Acquiring quality metrics after batch effect correction.
2025-10-10 06:30:04.21289 INFO::ASW Batch was 0.308064503981548 prior to batch effect correction and is now -0.0729092718608236 .
2025-10-10 06:30:04.213931 INFO::ASW Label was 0.279543196113314 prior to batch effect correction and is now 0.842812255912807 .
2025-10-10 06:30:04.215298 INFO::Total function execution time is  0.218476057052612  s and adjustment time is  0.191587209701538 s ( 87.69 )
2025-10-10 06:30:04.216657 INFO::Formatting Data.
2025-10-10 06:30:04.217666 INFO::Replacing NaNs with NAs.
2025-10-10 06:30:04.219055 INFO::Removing potential empty rows and columns
2025-10-10 06:30:04.220688 INFO::Found  0  missing values.
2025-10-10 06:30:04.227567 INFO::Introduced 0 missing values due to singular proteins at batch/covariate level.
2025-10-10 06:30:04.228601 INFO::Done
2025-10-10 06:30:04.229789 INFO::Acquiring quality metrics before batch effect correction.
2025-10-10 06:30:04.234545 INFO::Starting hierarchical adjustment
2025-10-10 06:30:04.235834 INFO::Found  5  batches.
2025-10-10 06:30:04.236773 INFO::Cores argument is not defined or BPPARAM has been specified. Argument corereduction will not be used.
2025-10-10 06:30:04.237803 INFO::Using default BPPARAM
2025-10-10 06:30:04.238696 INFO::Processing subtree level 1
design matrix of interest not specified. Assuming a one-group experiment.

design matrix of interest not specified. Assuming a one-group experiment.
design matrix of interest not specified. Assuming a one-group experiment.

2025-10-10 06:30:04.407033 INFO::Adjusting the last 2 batches sequentially
2025-10-10 06:30:04.409552 INFO::Adjusting sequential tree level 1 with 2 batches
design matrix of interest not specified. Assuming a one-group experiment.
2025-10-10 06:30:04.434621 INFO::Done
2025-10-10 06:30:04.435653 INFO::Acquiring quality metrics after batch effect correction.
2025-10-10 06:30:04.440782 INFO::ASW Batch was 0.308064503981548 prior to batch effect correction and is now -0.0729092718608236 .
2025-10-10 06:30:04.44183 INFO::ASW Label was 0.279543196113314 prior to batch effect correction and is now 0.842812255912807 .
2025-10-10 06:30:04.443099 INFO::Total function execution time is  0.226479053497314  s and adjustment time is  0.199022769927979 s ( 87.88 )
2025-10-10 06:30:04.464664 INFO::Formatting Data.
2025-10-10 06:30:04.46585 INFO::Replacing NaNs with NAs.
2025-10-10 06:30:04.467267 INFO::Removing potential empty rows and columns
2025-10-10 06:30:04.468902 INFO::Found  0  missing values.
2025-10-10 06:30:04.475638 INFO::Introduced 0 missing values due to singular proteins at batch/covariate level.
2025-10-10 06:30:04.476658 INFO::Done
2025-10-10 06:30:04.477532 INFO::Acquiring quality metrics before batch effect correction.
2025-10-10 06:30:04.482254 INFO::Starting hierarchical adjustment
2025-10-10 06:30:04.4836 INFO::Found  5  batches.
2025-10-10 06:30:04.484486 INFO::Cores argument is not defined or BPPARAM has been specified. Argument corereduction will not be used.
2025-10-10 06:30:04.492771 INFO::Using default BPPARAM
2025-10-10 06:30:04.494372 INFO::Processing subtree level 1
design matrix of interest not specified. Assuming a one-group experiment.

design matrix of interest not specified. Assuming a one-group experiment.
design matrix of interest not specified. Assuming a one-group experiment.

2025-10-10 06:30:04.662927 INFO::Adjusting the last 2 batches sequentially
2025-10-10 06:30:04.665393 INFO::Adjusting sequential tree level 1 with 2 batches
design matrix of interest not specified. Assuming a one-group experiment.
2025-10-10 06:30:04.690666 INFO::Done
2025-10-10 06:30:04.691645 INFO::Acquiring quality metrics after batch effect correction.
2025-10-10 06:30:04.696638 INFO::ASW Batch was 0.251544401732468 prior to batch effect correction and is now -0.0643475522898502 .
2025-10-10 06:30:04.697677 INFO::ASW Label was 0.404380808432494 prior to batch effect correction and is now 0.800462634287635 .
2025-10-10 06:30:04.698978 INFO::Total function execution time is  0.234398603439331  s and adjustment time is  0.207347631454468 s ( 88.46 )
2025-10-10 06:30:04.70028 INFO::Formatting Data.
2025-10-10 06:30:04.701268 INFO::Replacing NaNs with NAs.
2025-10-10 06:30:04.702658 INFO::Removing potential empty rows and columns
2025-10-10 06:30:04.704208 INFO::Found  0  missing values.
2025-10-10 06:30:04.710675 INFO::Introduced 0 missing values due to singular proteins at batch/covariate level.
2025-10-10 06:30:04.711651 INFO::Done
2025-10-10 06:30:04.712468 INFO::Acquiring quality metrics before batch effect correction.
2025-10-10 06:30:04.716943 INFO::Starting hierarchical adjustment
2025-10-10 06:30:04.718206 INFO::Found  5  batches.
2025-10-10 06:30:04.719061 INFO::Cores argument is not defined or BPPARAM has been specified. Argument corereduction will not be used.
2025-10-10 06:30:04.720022 INFO::Using default BPPARAM
2025-10-10 06:30:04.72087 INFO::Processing subtree level 1
design matrix of interest not specified. Assuming a one-group experiment.

design matrix of interest not specified. Assuming a one-group experiment.
design matrix of interest not specified. Assuming a one-group experiment.

2025-10-10 06:30:04.872088 INFO::Adjusting the last 2 batches sequentially
2025-10-10 06:30:04.882616 INFO::Adjusting sequential tree level 1 with 2 batches
design matrix of interest not specified. Assuming a one-group experiment.
2025-10-10 06:30:04.90622 INFO::Done
2025-10-10 06:30:04.90721 INFO::Acquiring quality metrics after batch effect correction.
2025-10-10 06:30:04.911899 INFO::ASW Batch was 0.251544401732468 prior to batch effect correction and is now -0.0643475522898502 .
2025-10-10 06:30:04.912841 INFO::ASW Label was 0.404380808432494 prior to batch effect correction and is now 0.800462634287635 .
2025-10-10 06:30:04.914042 INFO::Total function execution time is  0.213746309280396  s and adjustment time is  0.188241243362427 s ( 88.07 )
2025-10-10 06:30:04.933613 INFO::Formatting Data.
2025-10-10 06:30:04.934675 INFO::Replacing NaNs with NAs.
2025-10-10 06:30:04.935976 INFO::Removing potential empty rows and columns
2025-10-10 06:30:04.937501 INFO::Found  0  missing values.
2025-10-10 06:30:04.941547 INFO::Introduced 0 missing values due to singular proteins at batch/covariate level.
2025-10-10 06:30:04.942438 INFO::Done
2025-10-10 06:30:04.943217 INFO::Acquiring quality metrics before batch effect correction.
2025-10-10 06:30:04.947349 INFO::Starting hierarchical adjustment
2025-10-10 06:30:04.94845 INFO::Found  2  batches.
2025-10-10 06:30:04.949258 INFO::Cores argument is not defined or BPPARAM has been specified. Argument corereduction will not be used.
2025-10-10 06:30:04.95016 INFO::Using default BPPARAM
2025-10-10 06:30:04.950915 INFO::Adjusting the last 2 batches sequentially
2025-10-10 06:30:04.952222 INFO::Adjusting sequential tree level 1 with 2 batches
design matrix of interest not specified. Assuming a one-group experiment.
2025-10-10 06:30:04.973606 INFO::Done
2025-10-10 06:30:04.974517 INFO::Acquiring quality metrics after batch effect correction.
2025-10-10 06:30:04.978554 INFO::ASW Batch was 0.586917212287327 prior to batch effect correction and is now 0.0246294835695619 .
2025-10-10 06:30:04.979429 INFO::ASW Label was 0.49670190564563 prior to batch effect correction and is now 0.881934805873586 .
2025-10-10 06:30:04.980495 INFO::Total function execution time is  0.0469963550567627  s and adjustment time is  0.0253462791442871 s ( 53.93 )
2025-10-10 06:30:04.981637 INFO::Formatting Data.
2025-10-10 06:30:04.982483 INFO::Replacing NaNs with NAs.
2025-10-10 06:30:04.983727 INFO::Removing potential empty rows and columns
2025-10-10 06:30:04.985135 INFO::Found  0  missing values.
2025-10-10 06:30:04.98904 INFO::Introduced 0 missing values due to singular proteins at batch/covariate level.
2025-10-10 06:30:04.98988 INFO::Done
2025-10-10 06:30:04.99062 INFO::Acquiring quality metrics before batch effect correction.
2025-10-10 06:30:04.994625 INFO::Starting hierarchical adjustment
2025-10-10 06:30:04.995688 INFO::Found  2  batches.
2025-10-10 06:30:04.996447 INFO::Cores argument is not defined or BPPARAM has been specified. Argument corereduction will not be used.
2025-10-10 06:30:04.997337 INFO::Using default BPPARAM
2025-10-10 06:30:04.998118 INFO::Adjusting the last 2 batches sequentially
2025-10-10 06:30:04.999422 INFO::Adjusting sequential tree level 1 with 2 batches
design matrix of interest not specified. Assuming a one-group experiment.
2025-10-10 06:30:05.020401 INFO::Done
2025-10-10 06:30:05.021329 INFO::Acquiring quality metrics after batch effect correction.
2025-10-10 06:30:05.025368 INFO::ASW Batch was 0.586917212287327 prior to batch effect correction and is now 0.0246294835695619 .
2025-10-10 06:30:05.026231 INFO::ASW Label was 0.49670190564563 prior to batch effect correction and is now 0.881934805873586 .
2025-10-10 06:30:05.027324 INFO::Total function execution time is  0.0457057952880859  s and adjustment time is  0.0249049663543701 s ( 54.49 )
2025-10-10 06:30:05.042955 INFO::Formatting Data.
2025-10-10 06:30:05.043971 INFO::Replacing NaNs with NAs.
2025-10-10 06:30:05.045198 INFO::Removing potential empty rows and columns
2025-10-10 06:30:05.046473 INFO::Found  0  missing values.
2025-10-10 06:30:05.049473 INFO::Introduced 0 missing values due to singular proteins at batch/covariate level.
2025-10-10 06:30:05.050283 INFO::Done
2025-10-10 06:30:05.051019 INFO::Acquiring quality metrics before batch effect correction.
2025-10-10 06:30:05.053648 INFO::Starting hierarchical adjustment
2025-10-10 06:30:05.054679 INFO::Found  2  batches.
2025-10-10 06:30:05.055418 INFO::Cores argument is not defined or BPPARAM has been specified. Argument corereduction will not be used.
2025-10-10 06:30:05.056262 INFO::Using default BPPARAM
2025-10-10 06:30:05.05702 INFO::Adjusting the last 2 batches sequentially
2025-10-10 06:30:05.058319 INFO::Adjusting sequential tree level 1 with 2 batches
2025-10-10 06:30:05.103929 INFO::Done
2025-10-10 06:30:05.10488 INFO::Acquiring quality metrics after batch effect correction.
2025-10-10 06:30:05.107564 INFO::ASW Batch was -0.0577649340057663 prior to batch effect correction and is now -0.0907429693097225 .
2025-10-10 06:30:05.108712 INFO::Total function execution time is  0.0658128261566162  s and adjustment time is  0.049443244934082 s ( 75.13 )
2025-10-10 06:30:05.125216 INFO::Formatting Data.
2025-10-10 06:30:05.126271 INFO::Replacing NaNs with NAs.
2025-10-10 06:30:05.127489 INFO::Removing potential empty rows and columns
2025-10-10 06:30:05.128925 INFO::Found  0  missing values.
2025-10-10 06:30:05.130584 INFO::BERT requires at least 2 numeric values per batch/covariate level. This may reduce the number of adjustable features considerably, depending on the quantification technique.
2025-10-10 06:30:05.137394 INFO::Introduced 0 missing values due to singular proteins at batch/covariate level.
2025-10-10 06:30:05.138331 INFO::Done
2025-10-10 06:30:05.13911 INFO::Acquiring quality metrics before batch effect correction.
2025-10-10 06:30:05.14325 INFO::Starting hierarchical adjustment
2025-10-10 06:30:05.144347 INFO::Found  2  batches.
2025-10-10 06:30:05.145147 INFO::Cores argument is not defined or BPPARAM has been specified. Argument corereduction will not be used.
2025-10-10 06:30:05.14605 INFO::Using default BPPARAM
2025-10-10 06:30:05.146793 INFO::Adjusting the last 2 batches sequentially
2025-10-10 06:30:05.148144 INFO::Adjusting sequential tree level 1 with 2 batches
2025-10-10 06:30:05.171813 INFO::Done
2025-10-10 06:30:05.178424 INFO::Acquiring quality metrics after batch effect correction.
2025-10-10 06:30:05.183085 INFO::ASW Batch was 0.634633265116964 prior to batch effect correction and is now -0.0263241988084375 .
2025-10-10 06:30:05.184019 INFO::ASW Label was 0.450290155811969 prior to batch effect correction and is now 0.93090513096608 .
2025-10-10 06:30:05.185224 INFO::Total function execution time is  0.0600652694702148  s and adjustment time is  0.027658224105835 s ( 46.05 )
2025-10-10 06:30:05.186387 INFO::Formatting Data.
2025-10-10 06:30:05.18727 INFO::Replacing NaNs with NAs.
2025-10-10 06:30:05.188669 INFO::Removing potential empty rows and columns
2025-10-10 06:30:05.190187 INFO::Found  0  missing values.
2025-10-10 06:30:05.191525 INFO::BERT requires at least 2 numeric values per batch/covariate level. This may reduce the number of adjustable features considerably, depending on the quantification technique.
2025-10-10 06:30:05.198517 INFO::Introduced 0 missing values due to singular proteins at batch/covariate level.
2025-10-10 06:30:05.199492 INFO::Done
2025-10-10 06:30:05.200289 INFO::Acquiring quality metrics before batch effect correction.
2025-10-10 06:30:05.204651 INFO::Starting hierarchical adjustment
2025-10-10 06:30:05.205784 INFO::Found  2  batches.
2025-10-10 06:30:05.206595 INFO::Cores argument is not defined or BPPARAM has been specified. Argument corereduction will not be used.
2025-10-10 06:30:05.207514 INFO::Using default BPPARAM
2025-10-10 06:30:05.208296 INFO::Adjusting the last 2 batches sequentially
2025-10-10 06:30:05.209676 INFO::Adjusting sequential tree level 1 with 2 batches
2025-10-10 06:30:05.233496 INFO::Done
2025-10-10 06:30:05.234448 INFO::Acquiring quality metrics after batch effect correction.
2025-10-10 06:30:05.2385 INFO::ASW Batch was 0.634633265116964 prior to batch effect correction and is now -0.0263241988084375 .
2025-10-10 06:30:05.239368 INFO::ASW Label was 0.450290155811969 prior to batch effect correction and is now 0.93090513096608 .
2025-10-10 06:30:05.240459 INFO::Total function execution time is  0.0540785789489746  s and adjustment time is  0.027944803237915 s ( 51.67 )
2025-10-10 06:30:05.531733 INFO::Formatting Data.
2025-10-10 06:30:05.53273 INFO::Replacing NaNs with NAs.
2025-10-10 06:30:05.534141 INFO::Removing potential empty rows and columns
2025-10-10 06:30:05.535518 INFO::Found  0  missing values.
2025-10-10 06:30:05.539674 INFO::Introduced 0 missing values due to singular proteins at batch/covariate level.
2025-10-10 06:30:05.540522 INFO::Done
2025-10-10 06:30:05.541275 INFO::Acquiring quality metrics before batch effect correction.
2025-10-10 06:30:05.543949 INFO::Starting hierarchical adjustment
2025-10-10 06:30:05.54495 INFO::Found  3  batches.
2025-10-10 06:30:05.545688 INFO::Cores argument is not defined or BPPARAM has been specified. Argument corereduction will not be used.
2025-10-10 06:30:05.546496 INFO::Using default BPPARAM
2025-10-10 06:30:05.54722 INFO::Processing subtree level 1
2025-10-10 06:30:05.652818 INFO::Adjusting the last 1 batches sequentially
2025-10-10 06:30:05.655173 INFO::Done
2025-10-10 06:30:05.656034 INFO::Acquiring quality metrics after batch effect correction.
2025-10-10 06:30:05.659401 INFO::ASW Batch was -0.0592699159234903 prior to batch effect correction and is now -0.0592699159234903 .
2025-10-10 06:30:05.660796 INFO::Total function execution time is  0.129047632217407  s and adjustment time is  0.110400199890137 s ( 85.55 )
2025-10-10 06:30:05.662249 INFO::Formatting Data.
2025-10-10 06:30:05.663141 INFO::Typecasting input to dataframe.
2025-10-10 06:30:05.664181 INFO::Replacing NaNs with NAs.
2025-10-10 06:30:05.665481 INFO::Removing potential empty rows and columns
2025-10-10 06:30:05.667042 INFO::Found  0  missing values.
2025-10-10 06:30:05.671441 INFO::Introduced 0 missing values due to singular proteins at batch/covariate level.
2025-10-10 06:30:05.672361 INFO::Done
2025-10-10 06:30:05.673348 INFO::Acquiring quality metrics before batch effect correction.
2025-10-10 06:30:05.676144 INFO::Starting hierarchical adjustment
2025-10-10 06:30:05.677257 INFO::Found  3  batches.
2025-10-10 06:30:05.678123 INFO::Cores argument is not defined or BPPARAM has been specified. Argument corereduction will not be used.
2025-10-10 06:30:05.678999 INFO::Using default BPPARAM
2025-10-10 06:30:05.679751 INFO::Processing subtree level 1
2025-10-10 06:30:05.789532 INFO::Adjusting the last 1 batches sequentially
2025-10-10 06:30:05.791857 INFO::Done
2025-10-10 06:30:05.792734 INFO::Acquiring quality metrics after batch effect correction.
2025-10-10 06:30:05.796059 INFO::ASW Batch was -0.0592699159234903 prior to batch effect correction and is now -0.0592699159234903 .
2025-10-10 06:30:05.797511 INFO::Total function execution time is  0.135171175003052  s and adjustment time is  0.11482048034668 s ( 84.94 )
2025-10-10 06:30:05.815219 INFO::Formatting Data.
2025-10-10 06:30:05.816235 INFO::Typecasting input to dataframe.
2025-10-10 06:30:05.817402 INFO::Replacing NaNs with NAs.
2025-10-10 06:30:05.818648 INFO::Removing potential empty rows and columns
2025-10-10 06:30:05.820199 INFO::Found  0  missing values.
2025-10-10 06:30:05.824487 INFO::Introduced 0 missing values due to singular proteins at batch/covariate level.
2025-10-10 06:30:05.825451 INFO::Done
2025-10-10 06:30:05.826217 INFO::Acquiring quality metrics before batch effect correction.
2025-10-10 06:30:05.828967 INFO::Starting hierarchical adjustment
2025-10-10 06:30:05.830095 INFO::Found  3  batches.
2025-10-10 06:30:05.83094 INFO::Cores argument is not defined or BPPARAM has been specified. Argument corereduction will not be used.
2025-10-10 06:30:05.831869 INFO::Using default BPPARAM
2025-10-10 06:30:05.832683 INFO::Processing subtree level 1
2025-10-10 06:30:05.940937 INFO::Adjusting the last 1 batches sequentially
2025-10-10 06:30:05.943345 INFO::Done
2025-10-10 06:30:05.944194 INFO::Acquiring quality metrics after batch effect correction.
2025-10-10 06:30:05.947635 INFO::ASW Batch was 0.0635326898660412 prior to batch effect correction and is now 0.0635326898660412 .
2025-10-10 06:30:05.948984 INFO::Total function execution time is  0.133792400360107  s and adjustment time is  0.113481283187866 s ( 84.82 )
2025-10-10 06:30:06.124079 INFO::Formatting Data.
2025-10-10 06:30:06.125161 INFO::Replacing NaNs with NAs.
2025-10-10 06:30:06.126693 INFO::Removing potential empty rows and columns
2025-10-10 06:30:06.130711 INFO::Found  1000  missing values.
2025-10-10 06:30:06.158039 INFO::Introduced 0 missing values due to singular proteins at batch/covariate level.
2025-10-10 06:30:06.158954 INFO::Done
2025-10-10 06:30:06.159705 INFO::Acquiring quality metrics before batch effect correction.
2025-10-10 06:30:06.167229 INFO::Starting hierarchical adjustment
2025-10-10 06:30:06.168405 INFO::Found  10  batches.
2025-10-10 06:30:06.169205 INFO::Cores argument is not defined or BPPARAM has been specified. Argument corereduction will not be used.
2025-10-10 06:30:06.170084 INFO::Using default BPPARAM
2025-10-10 06:30:06.170827 INFO::Processing subtree level 1
2025-10-10 06:30:06.342091 INFO::Processing subtree level 2
2025-10-10 06:30:06.52886 INFO::Adjusting the last 1 batches sequentially
2025-10-10 06:30:06.531698 INFO::Done
2025-10-10 06:30:06.53253 INFO::Acquiring quality metrics after batch effect correction.
2025-10-10 06:30:06.540976 INFO::ASW Batch was 0.485043835316682 prior to batch effect correction and is now 0.485043835316682 .
2025-10-10 06:30:06.541974 INFO::ASW Label was 0.329738711835014 prior to batch effect correction and is now 0.329738711835014 .
2025-10-10 06:30:06.543379 INFO::Total function execution time is  0.419336080551147  s and adjustment time is  0.363543272018433 s ( 86.69 )
2025-10-10 06:30:06.544752 INFO::Formatting Data.
2025-10-10 06:30:06.545672 INFO::Replacing NaNs with NAs.
2025-10-10 06:30:06.547491 INFO::Removing potential empty rows and columns
2025-10-10 06:30:06.551977 INFO::Found  1000  missing values.
2025-10-10 06:30:06.580392 INFO::Introduced 0 missing values due to singular proteins at batch/covariate level.
2025-10-10 06:30:06.581357 INFO::Done
2025-10-10 06:30:06.582134 INFO::Acquiring quality metrics before batch effect correction.
2025-10-10 06:30:06.59003 INFO::Starting hierarchical adjustment
2025-10-10 06:30:06.591198 INFO::Found  10  batches.
2025-10-10 06:30:07.915755 INFO::Set up parallel execution backend with 2 workers
2025-10-10 06:30:07.917915 INFO::Processing subtree level 1 with 10 batches using 2 cores.
2025-10-10 06:30:09.491114 INFO::Adjusting the last 2 batches sequentially
2025-10-10 06:30:09.493546 INFO::Adjusting sequential tree level 1 with 2 batches
2025-10-10 06:30:09.519258 INFO::Done
2025-10-10 06:30:09.520118 INFO::Acquiring quality metrics after batch effect correction.
2025-10-10 06:30:09.52698 INFO::ASW Batch was 0.485043835316682 prior to batch effect correction and is now 0.485043835316682 .
2025-10-10 06:30:09.527833 INFO::ASW Label was 0.329738711835014 prior to batch effect correction and is now 0.329738711835014 .
2025-10-10 06:30:09.528906 INFO::Total function execution time is  2.98431420326233  s and adjustment time is  2.92826843261719 s ( 98.12 )
2025-10-10 06:30:09.71854 INFO::Formatting Data.
2025-10-10 06:30:09.719718 INFO::Replacing NaNs with NAs.
2025-10-10 06:30:09.721166 INFO::Removing potential empty rows and columns
2025-10-10 06:30:09.722941 INFO::Found  0  missing values.
2025-10-10 06:30:09.728962 INFO::Introduced 0 missing values due to singular proteins at batch/covariate level.
2025-10-10 06:30:09.72992 INFO::Done
2025-10-10 06:30:09.730742 INFO::Acquiring quality metrics before batch effect correction.
2025-10-10 06:30:09.734842 INFO::Starting hierarchical adjustment
2025-10-10 06:30:09.736103 INFO::Found  3  batches.
2025-10-10 06:30:09.737064 INFO::Cores argument is not defined or BPPARAM has been specified. Argument corereduction will not be used.
2025-10-10 06:30:09.738134 INFO::Using default BPPARAM
2025-10-10 06:30:09.739027 INFO::Processing subtree level 1
2025-10-10 06:30:09.87408 INFO::Adjusting the last 1 batches sequentially
2025-10-10 06:30:09.884613 INFO::Done
2025-10-10 06:30:09.885662 INFO::Acquiring quality metrics after batch effect correction.
2025-10-10 06:30:09.894472 INFO::ASW Batch was 0.199683879014517 prior to batch effect correction and is now -0.13918738645092 .
2025-10-10 06:30:09.895413 INFO::ASW Label was -0.204001280770499 prior to batch effect correction and is now -0.0520601163928212 .
2025-10-10 06:30:09.900789 INFO::Total function execution time is  0.178190231323242  s and adjustment time is  0.140742778778076 s ( 78.98 )
2025-10-10 06:30:10.084931 INFO::Formatting Data.
2025-10-10 06:30:10.085979 INFO::Replacing NaNs with NAs.
2025-10-10 06:30:10.087206 INFO::Removing potential empty rows and columns
2025-10-10 06:30:10.088745 INFO::Found  2  missing values.
2025-10-10 06:30:10.09299 INFO::Introduced 1 missing values due to singular proteins at batch/covariate level.
2025-10-10 06:30:10.093844 INFO::Done
2025-10-10 06:30:10.133513 INFO::Found NA in Reference column
2025-10-10 06:30:10.147854 INFO::Require at least two references per batch.
2025-10-10 06:30:10.177091 INFO::Formatting Data.
2025-10-10 06:30:10.178063 INFO::Recognized SummarizedExperiment
2025-10-10 06:30:10.178811 INFO::Typecasting input to dataframe.
2025-10-10 06:30:10.192906 INFO::Replacing NaNs with NAs.
2025-10-10 06:30:10.194527 INFO::Removing potential empty rows and columns
2025-10-10 06:30:10.200181 INFO::Found  0  missing values.
2025-10-10 06:30:10.211294 INFO::Introduced 0 missing values due to singular proteins at batch/covariate level.
2025-10-10 06:30:10.212218 INFO::Done
2025-10-10 06:30:10.233721 INFO::Formatting Data.
2025-10-10 06:30:10.234657 INFO::Recognized SummarizedExperiment
2025-10-10 06:30:10.23539 INFO::Typecasting input to dataframe.
2025-10-10 06:30:10.261139 INFO::Replacing NaNs with NAs.
2025-10-10 06:30:10.262767 INFO::Removing potential empty rows and columns
2025-10-10 06:30:10.268338 INFO::Found  0  missing values.
2025-10-10 06:30:10.286227 INFO::Introduced 0 missing values due to singular proteins at batch/covariate level.
2025-10-10 06:30:10.287135 INFO::Done
2025-10-10 06:30:10.308454 INFO::Formatting Data.
2025-10-10 06:30:10.309422 INFO::Recognized SummarizedExperiment
2025-10-10 06:30:10.310188 INFO::Typecasting input to dataframe.
2025-10-10 06:30:10.33474 INFO::Replacing NaNs with NAs.
2025-10-10 06:30:10.336061 INFO::Removing potential empty rows and columns
2025-10-10 06:30:10.337609 INFO::Found  0  missing values.
2025-10-10 06:30:10.338849 INFO::BERT requires at least 2 numeric values per batch/covariate level. This may reduce the number of adjustable features considerably, depending on the quantification technique.
2025-10-10 06:30:10.345284 INFO::Introduced 0 missing values due to singular proteins at batch/covariate level.
2025-10-10 06:30:10.346165 INFO::Done
2025-10-10 06:30:10.360384 INFO::Formatting Data.
2025-10-10 06:30:10.361413 INFO::Replacing NaNs with NAs.
2025-10-10 06:30:10.362596 INFO::Removing potential empty rows and columns
2025-10-10 06:30:10.364014 INFO::Found  0  missing values.
2025-10-10 06:30:10.368286 INFO::Introduced 0 missing values due to singular proteins at batch/covariate level.
2025-10-10 06:30:10.369196 INFO::Done
2025-10-10 06:30:10.394345 INFO::Formatting Data.
2025-10-10 06:30:10.395757 INFO::Replacing NaNs with NAs.
2025-10-10 06:30:10.397073 INFO::Removing potential empty rows and columns
2025-10-10 06:30:10.398626 INFO::Found  0  missing values.
2025-10-10 06:30:10.402979 INFO::Introduced 0 missing values due to singular proteins at batch/covariate level.
2025-10-10 06:30:10.40378 INFO::Done
2025-10-10 06:30:10.448798 INFO::Formatting Data.
2025-10-10 06:30:10.449889 INFO::Replacing NaNs with NAs.
2025-10-10 06:30:10.451394 INFO::Removing potential empty rows and columns
2025-10-10 06:30:10.453212 INFO::Found  1  missing values.
2025-10-10 06:30:10.457337 INFO::Introduced 0 missing values due to singular proteins at batch/covariate level.
2025-10-10 06:30:10.458383 INFO::Done
2025-10-10 06:30:10.486923 INFO::Formatting Data.
2025-10-10 06:30:10.487982 INFO::Replacing NaNs with NAs.
2025-10-10 06:30:10.489218 INFO::Removing potential empty rows and columns
2025-10-10 06:30:10.490587 INFO::Found  2  missing values.
2025-10-10 06:30:10.491933 INFO::BERT requires at least 2 numeric values per batch/covariate level. This may reduce the number of adjustable features considerably, depending on the quantification technique.
2025-10-10 06:30:10.495545 INFO::Introduced 4 missing values due to singular proteins at batch/covariate level.
2025-10-10 06:30:10.496474 INFO::Done
2025-10-10 06:30:10.511487 INFO::Formatting Data.
2025-10-10 06:30:10.512527 INFO::Replacing NaNs with NAs.
2025-10-10 06:30:10.513824 INFO::Removing potential empty rows and columns
2025-10-10 06:30:10.515216 INFO::Found  2  missing values.
2025-10-10 06:30:10.517633 INFO::Introduced 0 missing values due to singular proteins at batch/covariate level.
2025-10-10 06:30:10.518506 INFO::Done
2025-10-10 06:30:10.534306 INFO::Formatting Data.
2025-10-10 06:30:10.535376 INFO::Typecasting input to dataframe.
2025-10-10 06:30:10.536594 INFO::Replacing NaNs with NAs.
2025-10-10 06:30:10.537841 INFO::Removing potential empty rows and columns
2025-10-10 06:30:10.539329 INFO::Found  0  missing values.
2025-10-10 06:30:10.543813 INFO::Introduced 0 missing values due to singular proteins at batch/covariate level.
2025-10-10 06:30:10.544758 INFO::Done
[ FAIL 0 | WARN 0 | SKIP 0 | PASS 134 ]
> 
> proc.time()
   user  system elapsed 
 22.859   5.188  28.123 

Example timings

BERT.Rcheck/BERT-Ex.timings

nameusersystemelapsed
BERT32.143 1.93124.102
compute_asw0.0310.0040.036
count_existing0.0190.0000.019
generate_data_covariables0.0180.0000.017
generate_dataset0.0160.0000.016