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###
### Running command:
###
###   /Library/Frameworks/R.framework/Resources/bin/R CMD check --install=check:methylclock.install-out.txt --library=/Library/Frameworks/R.framework/Resources/library --no-vignettes --timings methylclock_1.17.0.tar.gz
###
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* using log directory ‘/Users/biocbuild/bbs-3.23-bioc/meat/methylclock.Rcheck’
* using R Under development (unstable) (2026-03-20 r89666)
* using platform: aarch64-apple-darwin23
* R was compiled by
    Apple clang version 17.0.0 (clang-1700.3.19.1)
    GNU Fortran (GCC) 14.2.0
* running under: macOS Tahoe 26.3.1
* using session charset: UTF-8
* current time: 2026-03-23 00:35:13 UTC
* using option ‘--no-vignettes’
* checking for file ‘methylclock/DESCRIPTION’ ... OK
* checking extension type ... Package
* this is package ‘methylclock’ version ‘1.17.0’
* package encoding: UTF-8
* checking package namespace information ... OK
* checking package dependencies ... OK
* checking if this is a source package ... OK
* checking if there is a namespace ... OK
* checking for hidden files and directories ... OK
* checking for portable file names ... OK
* checking for sufficient/correct file permissions ... OK
* checking whether package ‘methylclock’ can be installed ... OK
* used C++ compiler: ‘Apple clang version 17.0.0 (clang-1700.6.4.2)’
* used SDK: ‘MacOSX26.2.sdk’
* checking installed package size ... OK
* checking package directory ... OK
* checking ‘build’ directory ... OK
* checking DESCRIPTION meta-information ... NOTE
License stub is invalid DCF.
* checking top-level files ... OK
* checking for left-over files ... OK
* checking index information ... OK
* checking package subdirectories ... OK
* checking code files for non-ASCII characters ... OK
* checking R files for syntax errors ... OK
* checking whether the package can be loaded ... OK
* checking whether the package can be loaded with stated dependencies ... OK
* checking whether the package can be unloaded cleanly ... OK
* checking whether the namespace can be loaded with stated dependencies ... OK
* checking whether the namespace can be unloaded cleanly ... OK
* checking dependencies in R code ... NOTE
Unexported object imported by a ':::' call: ‘minfi:::projectCellType’
  See the note in ?`:::` about the use of this operator.
* checking S3 generic/method consistency ... OK
* checking replacement functions ... OK
* checking foreign function calls ... OK
* checking R code for possible problems ... NOTE
DNAmAge: no visible binding for global variable ‘coefHorvath’
DNAmAge: no visible binding for global variable ‘coefHannum’
DNAmAge: no visible binding for global variable ‘coefLevine’
DNAmAge: no visible binding for global variable ‘coefSkin’
DNAmAge: no visible binding for global variable ‘coefPedBE’
DNAmAge: no visible binding for global variable ‘coefWu’
DNAmAge: no visible binding for global variable ‘coefTL’
DNAmAge: no visible binding for global variable ‘coefBLUP’
DNAmAge: no visible binding for global variable ‘coefEN’
DNAmGA: no visible binding for global variable ‘coefKnightGA’
DNAmGA: no visible binding for global variable ‘coefBohlin’
DNAmGA: no visible binding for global variable ‘coefMayneGA’
DNAmGA: no visible binding for global variable ‘coefLeeGA’
DNAmGA: no visible binding for global variable ‘coefEPIC’
DNAmGA: no visible global function definition for
  ‘meffil.estimate.cell.counts.from.betas’
DNAmGA: no visible global function definition for ‘install.packages’
DNAmGA: no visible global function definition for ‘data’
DNAmGA: no visible binding for global variable ‘plCellCpGsThird’
checkClocks: no visible binding for global variable ‘MethylationData’
checkClocks: no visible binding for global variable ‘coefHorvath’
checkClocks: no visible binding for global variable ‘coefHannum’
checkClocks: no visible binding for global variable ‘coefLevine’
checkClocks: no visible binding for global variable ‘coefSkin’
checkClocks: no visible binding for global variable ‘coefPedBE’
checkClocks: no visible binding for global variable ‘coefWu’
checkClocks: no visible binding for global variable ‘coefTL’
checkClocks: no visible binding for global variable ‘coefBLUP’
checkClocks: no visible binding for global variable ‘coefEN’
checkClocksGA: no visible binding for global variable ‘coefKnightGA’
checkClocksGA: no visible binding for global variable ‘coefBohlin’
checkClocksGA: no visible binding for global variable ‘coefMayneGA’
checkClocksGA: no visible binding for global variable ‘coefLeeGA’
checkClocksGA: no visible binding for global variable ‘coefEPIC’
cpgs_imputation: no visible binding for global variable ‘cpgs.in’
plotCorClocks: no visible binding for global variable ‘method’
plotCorClocks: no visible binding for global variable ‘clock’
plotCorClocks: no visible binding for global variable ‘age’
plotCorClocks: no visible binding for global variable ‘..rr.label..’
plotCorClocks: no visible binding for global variable ‘..p.label..’
plotDNAmAge: no visible binding for global variable ‘..eq.label..’
plotDNAmAge: no visible binding for global variable ‘..rr.label..’
Undefined global functions or variables:
  ..eq.label.. ..p.label.. ..rr.label.. MethylationData age clock
  coefBLUP coefBohlin coefEN coefEPIC coefHannum coefHorvath
  coefKnightGA coefLeeGA coefLevine coefMayneGA coefPedBE coefSkin
  coefTL coefWu cpgs.in data install.packages
  meffil.estimate.cell.counts.from.betas method plCellCpGsThird
Consider adding
  importFrom("utils", "data", "install.packages")
to your NAMESPACE file.
* checking Rd files ... OK
* checking Rd metadata ... OK
* checking Rd cross-references ... OK
* checking for missing documentation entries ... OK
* checking for code/documentation mismatches ... OK
* checking Rd \usage sections ... OK
* checking Rd contents ... OK
* checking for unstated dependencies in examples ... OK
* checking contents of ‘data’ directory ... OK
* checking data for non-ASCII characters ... OK
* checking data for ASCII and uncompressed saves ... OK
* checking line endings in C/C++/Fortran sources/headers ... OK
* checking compiled code ... INFO
Note: information on .o files is not available
* checking files in ‘vignettes’ ... OK
* checking examples ... OK
Examples with CPU (user + system) or elapsed time > 5s
                          user system elapsed
commonClockCpgs         10.575  0.832  14.124
plotDNAmAge              9.797  0.664  12.567
DNAmAge                  9.794  0.620  12.346
checkClocks              9.467  0.843  12.399
load_DNAm_Clocks_data    7.464  0.494   9.577
load_DNAmGA_Clocks_data  7.378  0.524   9.823
DNAmGA                   4.942  0.341   6.343
checkClocksGA            4.020  0.328   5.282
* checking for unstated dependencies in vignettes ... OK
* checking package vignettes ... OK
* checking running R code from vignettes ... SKIPPED
* checking re-building of vignette outputs ... SKIPPED
* checking PDF version of manual ... OK
* DONE

Status: 3 NOTEs
See
  ‘/Users/biocbuild/bbs-3.23-bioc/meat/methylclock.Rcheck/00check.log’
for details.

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###
### Running command:
###
###   /Library/Frameworks/R.framework/Resources/bin/R CMD INSTALL methylclock
###
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* installing to library ‘/Library/Frameworks/R.framework/Versions/4.6/Resources/library’
* installing *source* package ‘methylclock’ ...
** this is package ‘methylclock’ version ‘1.17.0’
** using staged installation
** libs
using C++ compiler: ‘Apple clang version 17.0.0 (clang-1700.6.4.2)’
using SDK: ‘MacOSX26.2.sdk’
clang++ -arch arm64 -std=gnu++20 -I"/Library/Frameworks/R.framework/Resources/include" -DNDEBUG  -I'/Library/Frameworks/R.framework/Versions/4.6/Resources/library/Rcpp/include' -I/opt/R/arm64/include    -fPIC  -falign-functions=64 -Wall -g -O2   -c NewModel1Clean.cpp -o NewModel1Clean.o
NewModel1Clean.cpp:35:14: warning: variable length arrays in C++ are a Clang extension [-Wvla-cxx-extension]
   35 |   double b_y[isize];
      |              ^~~~~
NewModel1Clean.cpp:35:14: note: read of non-const variable 'isize' is not allowed in a constant expression
NewModel1Clean.cpp:34:16: note: declared here
   34 |   unsigned int isize = cpgs*samples;
      |                ^
NewModel1Clean.cpp:57:12: warning: variable length arrays in C++ are a Clang extension [-Wvla-cxx-extension]
   57 |   double a[sizeobs];
      |            ^~~~~~~
NewModel1Clean.cpp:57:12: note: function parameter 'sizeobs' with unknown value cannot be used in a constant expression
NewModel1Clean.cpp:54:65: note: declared here
   54 | static void mapminmax_reverse(const double y[], double x[], int sizeobs)
      |                                                                 ^
NewModel1Clean.cpp:271:14: warning: variable length arrays in C++ are a Clang extension [-Wvla-cxx-extension]
  271 |   double xp1[sizealloc];
      |              ^~~~~~~~~
NewModel1Clean.cpp:271:14: note: initializer of 'sizealloc' is not a constant expression
NewModel1Clean.cpp:118:13: note: declared here
  118 |   const int sizealloc = cpgs * samples;
      |             ^
NewModel1Clean.cpp:272:14: warning: variable length arrays in C++ are a Clang extension [-Wvla-cxx-extension]
  272 |   double dv1[sizeobs5];
      |              ^~~~~~~~
NewModel1Clean.cpp:272:14: note: initializer of 'sizeobs5' is not a constant expression
NewModel1Clean.cpp:120:13: note: declared here
  120 |   const int sizeobs5 = samples*5;
      |             ^
NewModel1Clean.cpp:273:14: warning: variable length arrays in C++ are a Clang extension [-Wvla-cxx-extension]
  273 |   double dv2[sizeobs5];
      |              ^~~~~~~~
NewModel1Clean.cpp:273:14: note: initializer of 'sizeobs5' is not a constant expression
NewModel1Clean.cpp:120:13: note: declared here
  120 |   const int sizeobs5 = samples*5;
      |             ^
NewModel1Clean.cpp:276:14: warning: variable length arrays in C++ are a Clang extension [-Wvla-cxx-extension]
  276 |   double dv3[samples];
      |              ^~~~~~~
NewModel1Clean.cpp:276:14: note: function parameter 'samples' with unknown value cannot be used in a constant expression
NewModel1Clean.cpp:115:75: note: declared here
  115 | void NewModel1Clean( Rcpp::NumericMatrix x1, double b_y1[], int cpgs, int samples)
      |                                                                           ^
6 warnings generated.
clang++ -arch arm64 -std=gnu++20 -I"/Library/Frameworks/R.framework/Resources/include" -DNDEBUG  -I'/Library/Frameworks/R.framework/Versions/4.6/Resources/library/Rcpp/include' -I/opt/R/arm64/include    -fPIC  -falign-functions=64 -Wall -g -O2   -c NewModel1Clean_emxAPI.cpp -o NewModel1Clean_emxAPI.o
clang++ -arch arm64 -std=gnu++20 -I"/Library/Frameworks/R.framework/Resources/include" -DNDEBUG  -I'/Library/Frameworks/R.framework/Versions/4.6/Resources/library/Rcpp/include' -I/opt/R/arm64/include    -fPIC  -falign-functions=64 -Wall -g -O2   -c NewModel1Clean_emxutil.cpp -o NewModel1Clean_emxutil.o
clang++ -arch arm64 -std=gnu++20 -I"/Library/Frameworks/R.framework/Resources/include" -DNDEBUG  -I'/Library/Frameworks/R.framework/Versions/4.6/Resources/library/Rcpp/include' -I/opt/R/arm64/include    -fPIC  -falign-functions=64 -Wall -g -O2   -c NewModel1Clean_initialize.cpp -o NewModel1Clean_initialize.o
clang++ -arch arm64 -std=gnu++20 -I"/Library/Frameworks/R.framework/Resources/include" -DNDEBUG  -I'/Library/Frameworks/R.framework/Versions/4.6/Resources/library/Rcpp/include' -I/opt/R/arm64/include    -fPIC  -falign-functions=64 -Wall -g -O2   -c NewModel1Clean_terminate.cpp -o NewModel1Clean_terminate.o
clang++ -arch arm64 -std=gnu++20 -I"/Library/Frameworks/R.framework/Resources/include" -DNDEBUG  -I'/Library/Frameworks/R.framework/Versions/4.6/Resources/library/Rcpp/include' -I/opt/R/arm64/include    -fPIC  -falign-functions=64 -Wall -g -O2   -c RcppExports.cpp -o RcppExports.o
clang++ -arch arm64 -std=gnu++20 -I"/Library/Frameworks/R.framework/Resources/include" -DNDEBUG  -I'/Library/Frameworks/R.framework/Versions/4.6/Resources/library/Rcpp/include' -I/opt/R/arm64/include    -fPIC  -falign-functions=64 -Wall -g -O2   -c bsxfun.cpp -o bsxfun.o
clang++ -arch arm64 -std=gnu++20 -I"/Library/Frameworks/R.framework/Resources/include" -DNDEBUG  -I'/Library/Frameworks/R.framework/Versions/4.6/Resources/library/Rcpp/include' -I/opt/R/arm64/include    -fPIC  -falign-functions=64 -Wall -g -O2   -c main.cpp -o main.o
main.cpp:58:15: warning: variable length arrays in C++ are a Clang extension [-Wvla-cxx-extension]
   58 |   double b_y1[isamples];
      |               ^~~~~~~~
main.cpp:58:15: note: read of non-const variable 'isamples' is not allowed in a constant expression
main.cpp:57:7: note: declared here
   57 |   int isamples= data.ncol(); // Samples
      |       ^
main.cpp:37:14: warning: unused function 'argInit_real_T' [-Wunused-function]
   37 | static float argInit_real_T()
      |              ^~~~~~~~~~~~~~
2 warnings generated.
clang++ -arch arm64 -std=gnu++20 -I"/Library/Frameworks/R.framework/Resources/include" -DNDEBUG  -I'/Library/Frameworks/R.framework/Versions/4.6/Resources/library/Rcpp/include' -I/opt/R/arm64/include    -fPIC  -falign-functions=64 -Wall -g -O2   -c repmat.cpp -o repmat.o
clang++ -arch arm64 -std=gnu++20 -I"/Library/Frameworks/R.framework/Resources/include" -DNDEBUG  -I'/Library/Frameworks/R.framework/Versions/4.6/Resources/library/Rcpp/include' -I/opt/R/arm64/include    -fPIC  -falign-functions=64 -Wall -g -O2   -c rtGetInf.cpp -o rtGetInf.o
clang++ -arch arm64 -std=gnu++20 -I"/Library/Frameworks/R.framework/Resources/include" -DNDEBUG  -I'/Library/Frameworks/R.framework/Versions/4.6/Resources/library/Rcpp/include' -I/opt/R/arm64/include    -fPIC  -falign-functions=64 -Wall -g -O2   -c rtGetNaN.cpp -o rtGetNaN.o
clang++ -arch arm64 -std=gnu++20 -I"/Library/Frameworks/R.framework/Resources/include" -DNDEBUG  -I'/Library/Frameworks/R.framework/Versions/4.6/Resources/library/Rcpp/include' -I/opt/R/arm64/include    -fPIC  -falign-functions=64 -Wall -g -O2   -c rt_nonfinite.cpp -o rt_nonfinite.o
clang++ -arch arm64 -std=gnu++20 -dynamiclib -Wl,-headerpad_max_install_names -undefined dynamic_lookup -L/Library/Frameworks/R.framework/Resources/lib -L/opt/R/arm64/lib -o methylclock.so NewModel1Clean.o NewModel1Clean_emxAPI.o NewModel1Clean_emxutil.o NewModel1Clean_initialize.o NewModel1Clean_terminate.o RcppExports.o bsxfun.o main.o repmat.o rtGetInf.o rtGetNaN.o rt_nonfinite.o -F/Library/Frameworks/R.framework/.. -framework R
installing to /Library/Frameworks/R.framework/Versions/4.6/Resources/library/00LOCK-methylclock/00new/methylclock/libs
** R
** data
** inst
** byte-compile and prepare package for lazy loading
No methods found in package ‘rtracklayer’ for request: ‘trackName<-’ when loading ‘AnnotationHubData’
Warning message:
replacing previous import ‘utils::findMatches’ by ‘S4Vectors::findMatches’ when loading ‘ExperimentHubData’ 
** help
*** installing help indices
** building package indices
** installing vignettes
** testing if installed package can be loaded from temporary location
Warning: replacing previous import ‘utils::findMatches’ by ‘S4Vectors::findMatches’ when loading ‘ExperimentHubData’
No methods found in package ‘rtracklayer’ for request: ‘trackName<-’ when loading ‘AnnotationHubData’
** checking absolute paths in shared objects and dynamic libraries
** testing if installed package can be loaded from final location
Warning: replacing previous import ‘utils::findMatches’ by ‘S4Vectors::findMatches’ when loading ‘ExperimentHubData’
No methods found in package ‘rtracklayer’ for request: ‘trackName<-’ when loading ‘AnnotationHubData’
** testing if installed package keeps a record of temporary installation path
* DONE (methylclock)