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###
### Running command:
###
###   /Library/Frameworks/R.framework/Resources/bin/R CMD check --install=check:circRNAprofiler.install-out.txt --library=/Library/Frameworks/R.framework/Resources/library --no-vignettes --timings circRNAprofiler_1.23.1.tar.gz
###
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* using log directory ‘/Users/biocbuild/bbs-3.22-bioc/meat/circRNAprofiler.Rcheck’
* using R version 4.5.1 Patched (2025-09-10 r88807)
* using platform: x86_64-apple-darwin20
* R was compiled by
    Apple clang version 14.0.0 (clang-1400.0.29.202)
    GNU Fortran (GCC) 14.2.0
* running under: macOS Monterey 12.7.6
* using session charset: UTF-8
* using option ‘--no-vignettes’
* checking for file ‘circRNAprofiler/DESCRIPTION’ ... OK
* checking extension type ... Package
* this is package ‘circRNAprofiler’ version ‘1.23.1’
* package encoding: UTF-8
* checking package namespace information ... OK
* checking package dependencies ... INFO
Imports includes 23 non-default packages.
Importing from so many packages makes the package vulnerable to any of
them becoming unavailable.  Move as many as possible to Suggests and
use conditionally.
* checking if this is a source package ... OK
* checking if there is a namespace ... OK
* checking for hidden files and directories ... OK
* checking for portable file names ... OK
* checking for sufficient/correct file permissions ... OK
* checking whether package ‘circRNAprofiler’ can be installed ... OK
* checking installed package size ... OK
* checking package directory ... OK
* checking ‘build’ directory ... OK
* checking DESCRIPTION meta-information ... OK
* checking top-level files ... OK
* checking for left-over files ... OK
* checking index information ... OK
* checking package subdirectories ... OK
* checking code files for non-ASCII characters ... OK
* checking R files for syntax errors ... OK
* checking whether the package can be loaded ... OK
* checking whether the package can be loaded with stated dependencies ... OK
* checking whether the package can be unloaded cleanly ... OK
* checking whether the namespace can be loaded with stated dependencies ... OK
* checking whether the namespace can be unloaded cleanly ... OK
* checking dependencies in R code ... OK
* checking S3 generic/method consistency ... OK
* checking replacement functions ... OK
* checking foreign function calls ... OK
* checking R code for possible problems ... NOTE
.fixCoordsWithGTF: no visible binding for global variable ‘startUpBSE’
.fixCoordsWithGTF: no visible binding for global variable ‘endDownBSE’
.fixCoordsWithGTF: no visible binding for global variable ‘start’
.fixCoordsWithGTF: no visible binding for global variable ‘end’
.getAllTranscripts: no visible binding for global variable ‘gene_name’
.getAllTranscripts: no visible binding for global variable ‘type’
.getAllTranscripts: no visible binding for global variable
  ‘transcript_id’
.getAllTranscripts: no visible binding for global variable ‘width’
.getAllTranscripts: no visible binding for global variable ‘len’
.getAntisenseCircRNAs: no visible binding for global variable
  ‘gene_name’
.getAntisenseCircRNAs: no visible binding for global variable ‘strand’
.getAntisenseCircRNAs: no visible binding for global variable ‘strand1’
.getAntisenseCircRNAs: no visible binding for global variable
  ‘gene_name1’
.getBSEsFromTranscript: no visible binding for global variable ‘start’
.getBSEsFromTranscript: no visible binding for global variable ‘end’
.getBSEsFromTranscript: no visible binding for global variable
  ‘exon_number’
.getCentralMatches: no visible binding for global variable ‘tm’
.getCentralMatches: no visible binding for global variable ‘cwcm’
.getCompensatoryMatches: no visible binding for global variable ‘tm’
.getCompensatoryMatches: no visible binding for global variable ‘cwcm’
.getComplRepeats: no visible binding for global variable ‘name’
.getComplRepeats: no visible binding for global variable ‘name.1’
.getComplRepeats: no visible binding for global variable ‘gr’
.getComplRepeats: no visible binding for global variable ‘gr.1’
.getComplRepeats: no visible binding for global variable ‘strand’
.getComplRepeats: no visible binding for global variable ‘strand.1’
.getFlankIntronFirst: no visible binding for global variable
  ‘exon_number’
.getFlankIntronLast: no visible binding for global variable
  ‘exon_number’
.getFlankIntrons: no visible binding for global variable ‘exon_number’
.getLengthBSEfi: no visible binding for global variable ‘endUpIntron’
.getLengthBSEfi: no visible binding for global variable ‘startUpIntron’
.getLengthBSEfi: no visible binding for global variable ‘endUpBSE’
.getLengthBSEfi: no visible binding for global variable ‘startUpBSE’
.getLengthBSEfi: no visible binding for global variable ‘endDownBSE’
.getLengthBSEfi: no visible binding for global variable ‘startDownBSE’
.getLengthBSEfi: no visible binding for global variable ‘endDownIntron’
.getLengthBSEfi: no visible binding for global variable
  ‘startDownIntron’
.getLengthBSEfi: no visible binding for global variable ‘lenUpBSE’
.getLengthBSEfi: no visible binding for global variable ‘lenDownBSE’
.getLengthBSEfi: no visible binding for global variable ‘lenUpIntron’
.getLengthBSEfi: no visible binding for global variable ‘lenDownIntron’
.getLengthBSEfi: no visible binding for global variable
  ‘meanLengthBSEs’
.getLengthBSEfi: no visible binding for global variable
  ‘meanLengthIntrons’
.getLengthCirc: no visible binding for global variable ‘exon_number’
.getLengthCirc: no visible binding for global variable ‘width’
.getRBPmotifsAttract: no visible binding for global variable ‘Organism’
.getRBPmotifsAttract: no visible binding for global variable
  ‘Gene_name’
.getRBPmotifsAttract: no visible binding for global variable ‘Motif’
.getRBPmotifsMEME: no visible binding for global variable ‘path’
.getSeedMatches: no visible binding for global variable ‘ncm’
.getSeedMatches: no visible binding for global variable ‘tm’
.getSeedMatches: no visible binding for global variable ‘cwcm’
.getTranscriptToAnalyze: no visible binding for global variable
  ‘transcript_id’
.getTranscriptToAnalyze: no visible binding for global variable
  ‘exon_number’
.grCoordsForNegative: no visible binding for global variable
  ‘startUpGR’
.grCoordsForNegative: no visible binding for global variable ‘endUpGR’
.grCoordsForNegative: no visible binding for global variable
  ‘startDownGR’
.grCoordsForNegative: no visible binding for global variable
  ‘endDownGR’
.grCoordsForPositive: no visible binding for global variable
  ‘startUpGR’
.grCoordsForPositive: no visible binding for global variable ‘endUpGR’
.grCoordsForPositive: no visible binding for global variable
  ‘startDownGR’
.grCoordsForPositive: no visible binding for global variable
  ‘endDownGR’
.matchWithKnowRBPs: no visible binding for global variable ‘motif’
.readGTF: no visible binding for global variable ‘type’
.readGTF: no visible binding for global variable ‘seqnames’
.readGTF: no visible binding for global variable ‘strand’
.readGTF: no visible binding for global variable ‘chrom’
.renameRepeats: no visible binding for global variable ‘name’
.renameRepeats: no visible binding for global variable ‘seqnames.1’
.renameRepeats: no visible binding for global variable ‘start.1’
.renameRepeats: no visible binding for global variable ‘end.1’
.renameRepeats: no visible binding for global variable ‘width.1’
.renameRepeats: no visible binding for global variable ‘strand.1’
.renameRepeats: no visible binding for global variable ‘score’
.renameSNPsGWAS: no visible binding for global variable ‘SNPS’
.renameSNPsGWAS: no visible binding for global variable ‘seqnames.1’
.renameSNPsGWAS: no visible binding for global variable ‘start.1’
.renameSNPsGWAS: no visible binding for global variable ‘MAPPED_GENE’
.renameSNPsGWAS: no visible binding for global variable ‘DISEASE.TRAIT’
.renameSNPsGWAS: no visible binding for global variable ‘P.VALUE’
.renameSNPsGWAS: no visible binding for global variable ‘CONTEXT’
.renameSNPsGWAS: no visible binding for global variable
  ‘STRONGEST.SNP.RISK.ALLELE’
.renameSNPsGWAS: no visible binding for global variable ‘PUBMEDID’
.renameSNPsGWAS: no visible binding for global variable ‘STUDY’
.reshapeCounts: no visible binding for global variable ‘motif’
.selectRandomBSEs: no visible binding for global variable ‘type’
.selectRandomBSEs: no visible binding for global variable
  ‘transcript_id’
.selectRandomBSEs: no visible binding for global variable ‘exon_number’
.splitRBPs: no visible binding for global variable ‘motif’
formatGTF: no visible binding for global variable ‘strand’
formatGTF: no visible binding for global variable ‘transcript_id’
formatGTF: no visible binding for global variable ‘start’
formatGTF: no visible binding for global variable ‘exon_number’
formatGTF: no visible binding for global variable ‘chrom’
getBackSplicedJunctions: no visible binding for global variable ‘name’
importCircExplorer2: no visible binding for global variable ‘circType’
importCircExplorer2: no visible binding for global variable ‘geneName’
importCircExplorer2: no visible binding for global variable ‘strand’
importCircExplorer2: no visible binding for global variable ‘chrom’
importCircExplorer2: no visible binding for global variable ‘start’
importCircExplorer2: no visible binding for global variable ‘end’
importCircExplorer2: no visible binding for global variable
  ‘readNumber’
importCircMarker: no visible binding for global variable ‘gene’
importCircMarker: no visible binding for global variable ‘strand’
importCircMarker: no visible binding for global variable ‘chrom’
importCircMarker: no visible binding for global variable ‘start’
importCircMarker: no visible binding for global variable ‘end’
importCircMarker: no visible binding for global variable ‘coverage’
importCircMarker: no visible binding for global variable ‘startUpBSE’
importCircMarker: no visible binding for global variable ‘endDownBSE’
importKnife: no visible binding for global variable ‘gene1_symbol’
importKnife: no visible binding for global variable ‘strand’
importKnife: no visible binding for global variable ‘chr’
importKnife: no visible binding for global variable ‘splice_position1’
importKnife: no visible binding for global variable ‘splice_position2’
importKnife: no visible binding for global variable ‘readNumber’
importKnife: no visible binding for global variable ‘chrom’
importMapSplice: no visible binding for global variable
  ‘annotated_gene_acceptor’
importMapSplice: no visible binding for global variable ‘strand’
importMapSplice: no visible binding for global variable ‘chrom’
importMapSplice: no visible binding for global variable
  ‘acceptor_start’
importMapSplice: no visible binding for global variable ‘doner_end’
importMapSplice: no visible binding for global variable ‘coverage’
importMapSplice: no visible binding for global variable ‘gene’
importMapSplice: no visible binding for global variable ‘startUpBSE’
importMapSplice: no visible binding for global variable ‘endDownBSE’
importNCLscan: no visible binding for global variable ‘type’
importNCLscan: no visible binding for global variable ‘gene’
importNCLscan: no visible binding for global variable ‘strand’
importNCLscan: no visible binding for global variable ‘chrom’
importNCLscan: no visible binding for global variable ‘startUpBSE’
importNCLscan: no visible binding for global variable ‘endDownBSE’
importNCLscan: no visible binding for global variable ‘coverage’
importOther: no visible binding for global variable ‘gene’
importOther: no visible binding for global variable ‘strand’
importOther: no visible binding for global variable ‘chrom’
importOther: no visible binding for global variable ‘startUpBSE’
importOther: no visible binding for global variable ‘endDownBSE’
importOther: no visible binding for global variable ‘coverage’
importUroborus: no visible binding for global variable
  ‘Parental_gene_name’
importUroborus: no visible binding for global variable ‘strand’
importUroborus: no visible binding for global variable ‘Chromosome’
importUroborus: no visible binding for global variable
  ‘start_of_junction’
importUroborus: no visible binding for global variable
  ‘end_of_junction’
importUroborus: no visible binding for global variable ‘read_counts’
importUroborus: no visible binding for global variable ‘chrom’
mergeBSJunctions: no visible binding for global variable ‘strand’
mergeBSJunctions: no visible binding for global variable ‘chrom’
mergeBSJunctions: no visible binding for global variable ‘startUpBSE’
mergeBSJunctions: no visible binding for global variable ‘endDownBSE’
mergeBSJunctions: no visible binding for global variable ‘tool’
mergeBSJunctions: no visible binding for global variable ‘mergedTools’
mergeBSJunctions: no visible binding for global variable ‘gene’
mergeMotifs: no visible binding for global variable ‘motif’
Undefined global functions or variables:
  CONTEXT Chromosome DISEASE.TRAIT Gene_name MAPPED_GENE Motif Organism
  P.VALUE PUBMEDID Parental_gene_name SNPS STRONGEST.SNP.RISK.ALLELE
  STUDY acceptor_start annotated_gene_acceptor chr chrom circType
  coverage cwcm doner_end end end.1 endDownBSE endDownGR endDownIntron
  endUpBSE endUpGR endUpIntron end_of_junction exon_number gene
  gene1_symbol geneName gene_name gene_name1 gr gr.1 len lenDownBSE
  lenDownIntron lenUpBSE lenUpIntron meanLengthBSEs meanLengthIntrons
  mergedTools motif name name.1 ncm path readNumber read_counts score
  seqnames seqnames.1 splice_position1 splice_position2 start start.1
  startDownBSE startDownGR startDownIntron startUpBSE startUpGR
  startUpIntron start_of_junction strand strand.1 strand1 tm tool
  transcript_id type width width.1
Consider adding
  importFrom("stats", "end", "start")
to your NAMESPACE file.
* checking Rd files ... OK
* checking Rd metadata ... OK
* checking Rd cross-references ... NOTE
Found the following Rd file(s) with Rd \link{} targets missing package
anchors:
  annotateRepeats.Rd: AnnotationHub
  getCircSeqs.Rd: getBSgenome
  getSeqsAcrossBSJs.Rd: getBSgenome
  getSeqsFromGRs.Rd: getBSgenome
Please provide package anchors for all Rd \link{} targets not in the
package itself and the base packages.
* checking for missing documentation entries ... OK
* checking for code/documentation mismatches ... OK
* checking Rd \usage sections ... OK
* checking Rd contents ... OK
* checking for unstated dependencies in examples ... OK
* checking contents of ‘data’ directory ... OK
* checking data for non-ASCII characters ... OK
* checking data for ASCII and uncompressed saves ... OK
* checking files in ‘vignettes’ ... OK
* checking examples ... OK
Examples with CPU (user + system) or elapsed time > 5s
                user system elapsed
liftBSJcoords 25.291  2.021  28.365
plotMotifs    19.051  0.200  28.381
getMotifs     12.325  0.144  17.392
mergeMotifs   12.296  0.160  23.761
getDeseqRes    5.103  0.127   5.258
* checking for unstated dependencies in ‘tests’ ... OK
* checking tests ...
  Running ‘testthat.R’
 OK
* checking for unstated dependencies in vignettes ... OK
* checking package vignettes ... OK
* checking running R code from vignettes ... SKIPPED
* checking re-building of vignette outputs ... SKIPPED
* checking PDF version of manual ... OK
* DONE

Status: 2 NOTEs
See
  ‘/Users/biocbuild/bbs-3.22-bioc/meat/circRNAprofiler.Rcheck/00check.log’
for details.

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###
### Running command:
###
###   /Library/Frameworks/R.framework/Resources/bin/R CMD INSTALL circRNAprofiler
###
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##############################################################################


* installing to library ‘/Library/Frameworks/R.framework/Versions/4.5-x86_64/Resources/library’
* installing *source* package ‘circRNAprofiler’ ...
** this is package ‘circRNAprofiler’ version ‘1.23.1’
** using staged installation
** R
** data
** inst
** byte-compile and prepare package for lazy loading
** help
*** installing help indices
** building package indices
** installing vignettes
** testing if installed package can be loaded from temporary location
** testing if installed package can be loaded from final location
** testing if installed package keeps a record of temporary installation path
* DONE (circRNAprofiler)

R version 4.5.1 Patched (2025-09-10 r88807) -- "Great Square Root"
Copyright (C) 2025 The R Foundation for Statistical Computing
Platform: x86_64-apple-darwin20

R is free software and comes with ABSOLUTELY NO WARRANTY.
You are welcome to redistribute it under certain conditions.
Type 'license()' or 'licence()' for distribution details.

R is a collaborative project with many contributors.
Type 'contributors()' for more information and
'citation()' on how to cite R or R packages in publications.

Type 'demo()' for some demos, 'help()' for on-line help, or
'help.start()' for an HTML browser interface to help.
Type 'q()' to quit R.

> library(testthat)
> library(circRNAprofiler)
> 
> test_check("circRNAprofiler")

Analysing: Ncoa6:-:chr2:155440785:155437860
Analysing: Arhgap5:+:chr12:52516079:52542636
Analysing: Arhgap5:+:chr12:52516079:52542636
Analysing: Pwwp2a:+:chr11:43704534:43705477trying URL 'https://attract.cnic.es/attract/static/ATtRACT.zip'
downloaded 113 KB

trying URL 'https://attract.cnic.es/attract/static/ATtRACT.zip'
downloaded 113 KB

trying URL 'https://attract.cnic.es/attract/static/ATtRACT.zip'
downloaded 113 KB

trying URL 'https://attract.cnic.es/attract/static/ATtRACT.zip'
downloaded 113 KB

trying URL 'https://attract.cnic.es/attract/static/ATtRACT.zip'
downloaded 113 KB

[ FAIL 0 | WARN 1 | SKIP 1 | PASS 255 ]

══ Skipped tests (1) ═══════════════════════════════════════════════════════════
• empty test (1): 'test_annotateRepeats.R:4:1'

[ FAIL 0 | WARN 1 | SKIP 1 | PASS 255 ]
> 
> proc.time()
   user  system elapsed 
143.937   4.145 171.516