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This page was generated on 2026-03-09 11:33 -0400 (Mon, 09 Mar 2026).

HostnameOSArch (*)R versionInstalled pkgs
nebbiolo1Linux (Ubuntu 24.04.3 LTS)x86_64R Under development (unstable) (2026-03-05 r89546) -- "Unsuffered Consequences" 4508
kjohnson3macOS 13.7.7 Venturaarm64R Under development (unstable) (2026-02-28 r89501) -- "Unsuffered Consequences" 3381
Click on any hostname to see more info about the system (e.g. compilers)      (*) as reported by 'uname -p', except on Windows and Mac OS X

Package 170/2360HostnameOS / ArchINSTALLBUILDCHECKBUILD BIN
BERT 1.7.0  (landing page)
Yannis Schumann
Snapshot Date: 2026-03-08 13:40 -0400 (Sun, 08 Mar 2026)
git_url: https://git.bioconductor.org/packages/BERT
git_branch: devel
git_last_commit: 2e49878
git_last_commit_date: 2025-10-29 11:26:54 -0400 (Wed, 29 Oct 2025)
nebbiolo1Linux (Ubuntu 24.04.3 LTS) / x86_64  OK    OK    OK  UNNEEDED, same version is already published
kjohnson3macOS 13.7.7 Ventura / arm64  OK    OK    OK    OK  UNNEEDED, same version is already published
See other builds for BERT in R Universe.


CHECK results for BERT on kjohnson3

To the developers/maintainers of the BERT package:
- Allow up to 24 hours (and sometimes 48 hours) for your latest push to git@git.bioconductor.org:packages/BERT.git to reflect on this report. See Troubleshooting Build Report for more information.
- Use the following Renviron settings to reproduce errors and warnings.
- If 'R CMD check' started to fail recently on the Linux builder(s) over a missing dependency, add the missing dependency to 'Suggests:' in your DESCRIPTION file. See Renviron.bioc for more information.

raw results


Summary

Package: BERT
Version: 1.7.0
Command: /Library/Frameworks/R.framework/Resources/bin/R CMD check --install=check:BERT.install-out.txt --library=/Library/Frameworks/R.framework/Resources/library --no-vignettes --timings BERT_1.7.0.tar.gz
StartedAt: 2026-03-08 16:35:48 -0400 (Sun, 08 Mar 2026)
EndedAt: 2026-03-08 16:36:19 -0400 (Sun, 08 Mar 2026)
EllapsedTime: 31.4 seconds
RetCode: 0
Status:   OK  
CheckDir: BERT.Rcheck
Warnings: 0

Command output

##############################################################################
##############################################################################
###
### Running command:
###
###   /Library/Frameworks/R.framework/Resources/bin/R CMD check --install=check:BERT.install-out.txt --library=/Library/Frameworks/R.framework/Resources/library --no-vignettes --timings BERT_1.7.0.tar.gz
###
##############################################################################
##############################################################################


* using log directory ‘/Users/biocbuild/bbs-3.23-bioc/meat/BERT.Rcheck’
* using R Under development (unstable) (2026-02-28 r89501)
* using platform: aarch64-apple-darwin20
* R was compiled by
    Apple clang version 16.0.0 (clang-1600.0.26.6)
    GNU Fortran (GCC) 14.2.0
* running under: macOS Sonoma 14.8.3
* using session charset: UTF-8
* current time: 2026-03-08 20:35:48 UTC
* using option ‘--no-vignettes’
* checking for file ‘BERT/DESCRIPTION’ ... OK
* this is package ‘BERT’ version ‘1.7.0’
* package encoding: UTF-8
* checking package namespace information ... OK
* checking package dependencies ... OK
* checking if this is a source package ... OK
* checking if there is a namespace ... OK
* checking for hidden files and directories ... OK
* checking for portable file names ... OK
* checking for sufficient/correct file permissions ... OK
* checking whether package ‘BERT’ can be installed ... OK
* checking installed package size ... OK
* checking package directory ... OK
* checking ‘build’ directory ... OK
* checking DESCRIPTION meta-information ... OK
* checking top-level files ... OK
* checking for left-over files ... OK
* checking index information ... OK
* checking package subdirectories ... OK
* checking code files for non-ASCII characters ... OK
* checking R files for syntax errors ... OK
* checking whether the package can be loaded ... OK
* checking whether the package can be loaded with stated dependencies ... OK
* checking whether the package can be unloaded cleanly ... OK
* checking whether the namespace can be loaded with stated dependencies ... OK
* checking whether the namespace can be unloaded cleanly ... OK
* checking dependencies in R code ... OK
* checking S3 generic/method consistency ... OK
* checking replacement functions ... OK
* checking foreign function calls ... OK
* checking R code for possible problems ... OK
* checking Rd files ... OK
* checking Rd metadata ... OK
* checking Rd cross-references ... OK
* checking for missing documentation entries ... OK
* checking for code/documentation mismatches ... OK
* checking Rd \usage sections ... OK
* checking Rd contents ... OK
* checking for unstated dependencies in examples ... OK
* checking files in ‘vignettes’ ... OK
* checking examples ... OK
Examples with CPU (user + system) or elapsed time > 5s
      user system elapsed
BERT 9.291  0.436   6.878
* checking for unstated dependencies in ‘tests’ ... OK
* checking tests ...
  Running ‘testthat.R’
 OK
* checking for unstated dependencies in vignettes ... OK
* checking package vignettes ... OK
* checking running R code from vignettes ... SKIPPED
* checking re-building of vignette outputs ... SKIPPED
* checking PDF version of manual ... OK
* DONE

Status: OK


Installation output

BERT.Rcheck/00install.out

##############################################################################
##############################################################################
###
### Running command:
###
###   /Library/Frameworks/R.framework/Resources/bin/R CMD INSTALL BERT
###
##############################################################################
##############################################################################


* installing to library ‘/Library/Frameworks/R.framework/Versions/4.6-arm64/Resources/library’
* installing *source* package ‘BERT’ ...
** this is package ‘BERT’ version ‘1.7.0’
** using staged installation
** R
** inst
** byte-compile and prepare package for lazy loading
** help
*** installing help indices
** building package indices
** installing vignettes
** testing if installed package can be loaded from temporary location
** testing if installed package can be loaded from final location
** testing if installed package keeps a record of temporary installation path
* DONE (BERT)

Tests output

BERT.Rcheck/tests/testthat.Rout


R Under development (unstable) (2026-02-28 r89501) -- "Unsuffered Consequences"
Copyright (C) 2026 The R Foundation for Statistical Computing
Platform: aarch64-apple-darwin20

R is free software and comes with ABSOLUTELY NO WARRANTY.
You are welcome to redistribute it under certain conditions.
Type 'license()' or 'licence()' for distribution details.

R is a collaborative project with many contributors.
Type 'contributors()' for more information and
'citation()' on how to cite R or R packages in publications.

Type 'demo()' for some demos, 'help()' for on-line help, or
'help.start()' for an HTML browser interface to help.
Type 'q()' to quit R.

> # This file is part of the standard setup for testthat.
> # It is recommended that you do not modify it.
> #
> # Where should you do additional test configuration?
> # Learn more about the roles of various files in:
> # * https://r-pkgs.org/tests.html
> # * https://testthat.r-lib.org/reference/test_package.html#special-files
> 
> library(testthat)
> library(BERT)
> 
> test_check("BERT")
2026-03-08 16:36:11.57903 INFO::Formatting Data.
2026-03-08 16:36:11.580431 INFO::Replacing NaNs with NAs.
2026-03-08 16:36:11.584912 INFO::Removing potential empty rows and columns
2026-03-08 16:36:11.681875 INFO::Found  0  missing values.
2026-03-08 16:36:11.6831 INFO::Introduced 0 missing values due to singular proteins at batch/covariate level.
2026-03-08 16:36:11.68332 INFO::Done
2026-03-08 16:36:11.683517 INFO::Acquiring quality metrics before batch effect correction.
2026-03-08 16:36:11.691213 INFO::Starting hierarchical adjustment
2026-03-08 16:36:11.691528 INFO::Found  3  batches.
2026-03-08 16:36:11.691738 INFO::Cores argument is not defined or BPPARAM has been specified. Argument corereduction will not be used.
2026-03-08 16:36:11.692151 INFO::Using default BPPARAM
2026-03-08 16:36:11.692353 INFO::Processing subtree level 1
2026-03-08 16:36:11.762669 INFO::Adjusting the last 1 batches sequentially
2026-03-08 16:36:11.763627 INFO::Done
2026-03-08 16:36:11.763851 INFO::Acquiring quality metrics after batch effect correction.
2026-03-08 16:36:11.764881 INFO::ASW Batch was -0.0991305283688797 prior to batch effect correction and is now -0.0991305283688797 .
2026-03-08 16:36:11.765323 INFO::Total function execution time is  0.186650991439819  s and adjustment time is  0.0721571445465088 s ( 38.66 )
2026-03-08 16:36:11.772283 INFO::Formatting Data.
2026-03-08 16:36:11.772935 INFO::Replacing NaNs with NAs.
2026-03-08 16:36:11.773247 INFO::Removing potential empty rows and columns
2026-03-08 16:36:11.773661 INFO::Found  0  missing values.
2026-03-08 16:36:11.773998 INFO::BERT requires at least 2 numeric values per batch/covariate level. This may reduce the number of adjustable features considerably, depending on the quantification technique.
2026-03-08 16:36:11.778759 INFO::Formatting Data.
2026-03-08 16:36:11.779013 INFO::Replacing NaNs with NAs.
2026-03-08 16:36:11.779348 INFO::Removing potential empty rows and columns
2026-03-08 16:36:11.779823 INFO::Found  0  missing values.
2026-03-08 16:36:11.780165 INFO::BERT requires at least 2 numeric values per batch/covariate level. This may reduce the number of adjustable features considerably, depending on the quantification technique.
2026-03-08 16:36:11.787918 INFO::Formatting Data.
2026-03-08 16:36:11.788187 INFO::Replacing NaNs with NAs.
2026-03-08 16:36:11.788535 INFO::Removing potential empty rows and columns
2026-03-08 16:36:11.788935 INFO::Found  0  missing values.
2026-03-08 16:36:11.789272 INFO::BERT requires at least 2 numeric values per batch/covariate level. This may reduce the number of adjustable features considerably, depending on the quantification technique.
2026-03-08 16:36:11.790879 INFO::Introduced 0 missing values due to singular proteins at batch/covariate level.
2026-03-08 16:36:11.79109 INFO::Done
2026-03-08 16:36:11.791283 INFO::Acquiring quality metrics before batch effect correction.
2026-03-08 16:36:11.792081 INFO::Starting hierarchical adjustment
2026-03-08 16:36:11.792335 INFO::Found  2  batches.
2026-03-08 16:36:11.792519 INFO::Cores argument is not defined or BPPARAM has been specified. Argument corereduction will not be used.
2026-03-08 16:36:11.792784 INFO::Using default BPPARAM
2026-03-08 16:36:11.792966 INFO::Adjusting the last 2 batches sequentially
2026-03-08 16:36:11.793287 INFO::Adjusting sequential tree level 1 with 2 batches
2026-03-08 16:36:11.804112 INFO::Done
2026-03-08 16:36:11.804417 INFO::Acquiring quality metrics after batch effect correction.
2026-03-08 16:36:11.805354 INFO::ASW Batch was 0.00131347874322548 prior to batch effect correction and is now -0.115962632132718 .
2026-03-08 16:36:11.805635 INFO::Total function execution time is  0.0177531242370605  s and adjustment time is  0.0118038654327393 s ( 66.49 )
2026-03-08 16:36:11.806995 INFO::Formatting Data.
2026-03-08 16:36:11.807241 INFO::Replacing NaNs with NAs.
2026-03-08 16:36:11.810592 INFO::Formatting Data.
2026-03-08 16:36:11.810835 INFO::Replacing NaNs with NAs.
2026-03-08 16:36:11.811132 INFO::Removing potential empty rows and columns
2026-03-08 16:36:11.811503 INFO::Found  0  missing values.
2026-03-08 16:36:11.812436 INFO::Introduced 0 missing values due to singular proteins at batch/covariate level.
2026-03-08 16:36:11.812655 INFO::Done
2026-03-08 16:36:11.812829 INFO::Acquiring quality metrics before batch effect correction.
2026-03-08 16:36:11.813493 INFO::Starting hierarchical adjustment
2026-03-08 16:36:11.813713 INFO::Found  2  batches.
2026-03-08 16:36:11.814241 INFO::Cores argument is not defined or BPPARAM has been specified. Argument corereduction will not be used.
2026-03-08 16:36:11.814441 INFO::Using default BPPARAM
2026-03-08 16:36:11.814619 INFO::Adjusting the last 2 batches sequentially
2026-03-08 16:36:11.81492 INFO::Adjusting sequential tree level 1 with 2 batches
design matrix of interest not specified. Assuming a one-group experiment.
2026-03-08 16:36:11.820998 INFO::Done
2026-03-08 16:36:11.82124 INFO::Acquiring quality metrics after batch effect correction.
2026-03-08 16:36:11.821911 INFO::ASW Batch was 0.0387820793431815 prior to batch effect correction and is now -0.124289870732453 .
2026-03-08 16:36:11.822164 INFO::Total function execution time is  0.0115830898284912  s and adjustment time is  0.00732183456420898 s ( 63.21 )
2026-03-08 16:36:11.822511 INFO::Formatting Data.
2026-03-08 16:36:11.822704 INFO::Replacing NaNs with NAs.
2026-03-08 16:36:11.823083 INFO::Removing potential empty rows and columns
2026-03-08 16:36:11.823549 INFO::Found  0  missing values.
2026-03-08 16:36:11.824859 INFO::Introduced 0 missing values due to singular proteins at batch/covariate level.
2026-03-08 16:36:11.825078 INFO::Done
2026-03-08 16:36:11.825302 INFO::Acquiring quality metrics before batch effect correction.
2026-03-08 16:36:11.826048 INFO::Starting hierarchical adjustment
2026-03-08 16:36:11.826328 INFO::Found  2  batches.
2026-03-08 16:36:11.826533 INFO::Cores argument is not defined or BPPARAM has been specified. Argument corereduction will not be used.
2026-03-08 16:36:11.826733 INFO::Using default BPPARAM
2026-03-08 16:36:11.826912 INFO::Adjusting the last 2 batches sequentially
2026-03-08 16:36:11.827153 INFO::Adjusting sequential tree level 1 with 2 batches
design matrix of interest not specified. Assuming a one-group experiment.
2026-03-08 16:36:11.832219 INFO::Done
2026-03-08 16:36:11.832463 INFO::Acquiring quality metrics after batch effect correction.
2026-03-08 16:36:11.833153 INFO::ASW Batch was 0.0387820793431815 prior to batch effect correction and is now -0.124289870732453 .
2026-03-08 16:36:11.833406 INFO::Total function execution time is  0.0108799934387207  s and adjustment time is  0.0059208869934082 s ( 54.42 )
Warning: stack imbalance in '::', 79 then 81
Warning: stack imbalance in '=', 77 then 79
2026-03-08 16:36:13.000451 INFO::Formatting Data.
2026-03-08 16:36:13.000695 INFO::Recognized SummarizedExperiment
2026-03-08 16:36:13.000852 INFO::Typecasting input to dataframe.
2026-03-08 16:36:13.01044 INFO::Replacing NaNs with NAs.
2026-03-08 16:36:13.010805 INFO::Removing potential empty rows and columns
2026-03-08 16:36:13.011857 INFO::Found  0  missing values.
2026-03-08 16:36:13.013852 INFO::Introduced 0 missing values due to singular proteins at batch/covariate level.
2026-03-08 16:36:13.014012 INFO::Done
2026-03-08 16:36:13.014157 INFO::Acquiring quality metrics before batch effect correction.
2026-03-08 16:36:13.015246 INFO::Starting hierarchical adjustment
2026-03-08 16:36:13.015437 INFO::Found  2  batches.
2026-03-08 16:36:13.015571 INFO::Cores argument is not defined or BPPARAM has been specified. Argument corereduction will not be used.
2026-03-08 16:36:13.015856 INFO::Using default BPPARAM
2026-03-08 16:36:13.015991 INFO::Adjusting the last 2 batches sequentially
2026-03-08 16:36:13.016246 INFO::Adjusting sequential tree level 1 with 2 batches
2026-03-08 16:36:13.033857 INFO::Done
2026-03-08 16:36:13.034121 INFO::Acquiring quality metrics after batch effect correction.
2026-03-08 16:36:13.035328 INFO::ASW Batch was -0.00179612624533465 prior to batch effect correction and is now -0.0891247418036357 .
2026-03-08 16:36:13.0356 INFO::Total function execution time is  0.0352411270141602  s and adjustment time is  0.0184459686279297 s ( 52.34 )
Warning: stack imbalance in '{', 73 then 75
2026-03-08 16:36:13.042554 INFO::Formatting Data.
2026-03-08 16:36:13.042806 INFO::Recognized SummarizedExperiment
2026-03-08 16:36:13.042975 INFO::Typecasting input to dataframe.
2026-03-08 16:36:13.046021 INFO::Replacing NaNs with NAs.
2026-03-08 16:36:13.046402 INFO::Removing potential empty rows and columns
2026-03-08 16:36:13.047552 INFO::Found  0  missing values.
2026-03-08 16:36:13.050048 INFO::Introduced 0 missing values due to singular proteins at batch/covariate level.
2026-03-08 16:36:13.050333 INFO::Done
2026-03-08 16:36:13.050515 INFO::Acquiring quality metrics before batch effect correction.
2026-03-08 16:36:13.051746 INFO::Starting hierarchical adjustment
2026-03-08 16:36:13.052006 INFO::Found  2  batches.
2026-03-08 16:36:13.05216 INFO::Cores argument is not defined or BPPARAM has been specified. Argument corereduction will not be used.
2026-03-08 16:36:13.05234 INFO::Using default BPPARAM
2026-03-08 16:36:13.052482 INFO::Adjusting the last 2 batches sequentially
2026-03-08 16:36:13.052767 INFO::Adjusting sequential tree level 1 with 2 batches
2026-03-08 16:36:13.060728 INFO::Done
2026-03-08 16:36:13.060934 INFO::Acquiring quality metrics after batch effect correction.
2026-03-08 16:36:13.062044 INFO::ASW Batch was 0.000416331458518238 prior to batch effect correction and is now 0.000416331458518238 .
2026-03-08 16:36:13.062299 INFO::Total function execution time is  0.0197479724884033  s and adjustment time is  0.00876188278198242 s ( 44.37 )
2026-03-08 16:36:13.081001 INFO::Formatting Data.
2026-03-08 16:36:13.081243 INFO::Replacing NaNs with NAs.
2026-03-08 16:36:13.081503 INFO::Removing potential empty rows and columns
2026-03-08 16:36:13.081789 INFO::Found  0  missing values.
2026-03-08 16:36:13.082551 INFO::Introduced 0 missing values due to singular proteins at batch/covariate level.
2026-03-08 16:36:13.082701 INFO::Done
2026-03-08 16:36:13.082835 INFO::Acquiring quality metrics before batch effect correction.
2026-03-08 16:36:13.083419 INFO::Starting hierarchical adjustment
2026-03-08 16:36:13.083598 INFO::Found  3  batches.
2026-03-08 16:36:13.083727 INFO::Cores argument is not defined or BPPARAM has been specified. Argument corereduction will not be used.
2026-03-08 16:36:13.083882 INFO::Using default BPPARAM
2026-03-08 16:36:13.084007 INFO::Processing subtree level 1
2026-03-08 16:36:13.226608 INFO::Adjusting the last 1 batches sequentially
2026-03-08 16:36:13.227747 INFO::Done
2026-03-08 16:36:13.228068 INFO::Acquiring quality metrics after batch effect correction.
2026-03-08 16:36:13.229399 INFO::ASW Batch was -0.0826739527067834 prior to batch effect correction and is now -0.156983438477216 .
2026-03-08 16:36:13.229913 INFO::Total function execution time is  0.148907899856567  s and adjustment time is  0.144171953201294 s ( 96.82 )
2026-03-08 16:36:13.238206 INFO::Skipping initial DF formatting
2026-03-08 16:36:13.238559 INFO::Acquiring quality metrics before batch effect correction.
2026-03-08 16:36:13.240616 INFO::Starting hierarchical adjustment
2026-03-08 16:36:13.240991 INFO::Found  5  batches.
2026-03-08 16:36:13.24125 INFO::Cores argument is not defined or BPPARAM has been specified. Argument corereduction will not be used.
2026-03-08 16:36:13.241573 INFO::Using default BPPARAM
2026-03-08 16:36:13.241824 INFO::Processing subtree level 1
2026-03-08 16:36:13.329 INFO::Adjusting the last 2 batches sequentially
2026-03-08 16:36:13.329757 INFO::Adjusting sequential tree level 1 with 2 batches
2026-03-08 16:36:13.337786 INFO::Done
2026-03-08 16:36:13.338091 INFO::Acquiring quality metrics after batch effect correction.
2026-03-08 16:36:13.339754 INFO::ASW Batch was 0.521859897712673 prior to batch effect correction and is now 0.521859897712673 .
2026-03-08 16:36:13.339964 INFO::ASW Label was 0.362812877865959 prior to batch effect correction and is now 0.362812877865959 .
2026-03-08 16:36:13.34031 INFO::Total function execution time is  0.102115869522095  s and adjustment time is  0.0968689918518066 s ( 94.86 )
2026-03-08 16:36:13.34811 INFO::Formatting Data.
2026-03-08 16:36:13.348374 INFO::Replacing NaNs with NAs.
2026-03-08 16:36:13.348699 INFO::Removing potential empty rows and columns
2026-03-08 16:36:13.349074 INFO::Found  0  missing values.
2026-03-08 16:36:13.350553 INFO::Introduced 0 missing values due to singular proteins at batch/covariate level.
2026-03-08 16:36:13.350735 INFO::Done
2026-03-08 16:36:13.350911 INFO::Acquiring quality metrics before batch effect correction.
2026-03-08 16:36:13.351869 INFO::Starting hierarchical adjustment
2026-03-08 16:36:13.35211 INFO::Found  5  batches.
2026-03-08 16:36:13.352289 INFO::Cores argument is not defined or BPPARAM has been specified. Argument corereduction will not be used.
2026-03-08 16:36:13.352496 INFO::Using default BPPARAM
2026-03-08 16:36:13.352674 INFO::Processing subtree level 1
design matrix of interest not specified. Assuming a one-group experiment.

design matrix of interest not specified. Assuming a one-group experiment.
design matrix of interest not specified. Assuming a one-group experiment.

2026-03-08 16:36:13.429392 INFO::Adjusting the last 2 batches sequentially
2026-03-08 16:36:13.430785 INFO::Adjusting sequential tree level 1 with 2 batches
design matrix of interest not specified. Assuming a one-group experiment.
2026-03-08 16:36:13.438282 INFO::Done
2026-03-08 16:36:13.438535 INFO::Acquiring quality metrics after batch effect correction.
2026-03-08 16:36:13.440006 INFO::ASW Batch was 0.585941054994118 prior to batch effect correction and is now -0.0773222245138409 .
2026-03-08 16:36:13.44023 INFO::ASW Label was 0.220356741540406 prior to batch effect correction and is now 0.76162358259809 .
2026-03-08 16:36:13.440612 INFO::Total function execution time is  0.0924849510192871  s and adjustment time is  0.0862131118774414 s ( 93.22 )
2026-03-08 16:36:13.440937 INFO::Formatting Data.
2026-03-08 16:36:13.441144 INFO::Replacing NaNs with NAs.
2026-03-08 16:36:13.441481 INFO::Removing potential empty rows and columns
2026-03-08 16:36:13.441899 INFO::Found  0  missing values.
2026-03-08 16:36:13.443432 INFO::Introduced 0 missing values due to singular proteins at batch/covariate level.
2026-03-08 16:36:13.443647 INFO::Done
2026-03-08 16:36:13.443839 INFO::Acquiring quality metrics before batch effect correction.
2026-03-08 16:36:13.444916 INFO::Starting hierarchical adjustment
2026-03-08 16:36:13.445189 INFO::Found  5  batches.
2026-03-08 16:36:13.445404 INFO::Cores argument is not defined or BPPARAM has been specified. Argument corereduction will not be used.
2026-03-08 16:36:13.445704 INFO::Using default BPPARAM
2026-03-08 16:36:13.445959 INFO::Processing subtree level 1
design matrix of interest not specified. Assuming a one-group experiment.

design matrix of interest not specified. Assuming a one-group experiment.
design matrix of interest not specified. Assuming a one-group experiment.

2026-03-08 16:36:13.527876 INFO::Adjusting the last 2 batches sequentially
2026-03-08 16:36:13.528835 INFO::Adjusting sequential tree level 1 with 2 batches
design matrix of interest not specified. Assuming a one-group experiment.
2026-03-08 16:36:13.536943 INFO::Done
2026-03-08 16:36:13.537228 INFO::Acquiring quality metrics after batch effect correction.
2026-03-08 16:36:13.53874 INFO::ASW Batch was 0.585941054994118 prior to batch effect correction and is now -0.0773222245138409 .
2026-03-08 16:36:13.539001 INFO::ASW Label was 0.220356741540406 prior to batch effect correction and is now 0.76162358259809 .
2026-03-08 16:36:13.539358 INFO::Total function execution time is  0.0983779430389404  s and adjustment time is  0.0917949676513672 s ( 93.31 )
2026-03-08 16:36:13.546714 INFO::Formatting Data.
2026-03-08 16:36:13.547034 INFO::Replacing NaNs with NAs.
2026-03-08 16:36:13.547444 INFO::Removing potential empty rows and columns
2026-03-08 16:36:13.547867 INFO::Found  0  missing values.
2026-03-08 16:36:13.549455 INFO::Introduced 0 missing values due to singular proteins at batch/covariate level.
2026-03-08 16:36:13.549672 INFO::Done
2026-03-08 16:36:13.549862 INFO::Acquiring quality metrics before batch effect correction.
2026-03-08 16:36:13.551 INFO::Starting hierarchical adjustment
2026-03-08 16:36:13.551286 INFO::Found  5  batches.
2026-03-08 16:36:13.551482 INFO::Cores argument is not defined or BPPARAM has been specified. Argument corereduction will not be used.
2026-03-08 16:36:13.55174 INFO::Using default BPPARAM
2026-03-08 16:36:13.551965 INFO::Processing subtree level 1
design matrix of interest not specified. Assuming a one-group experiment.

design matrix of interest not specified. Assuming a one-group experiment.
design matrix of interest not specified. Assuming a one-group experiment.

2026-03-08 16:36:13.641564 INFO::Adjusting the last 2 batches sequentially
2026-03-08 16:36:13.642345 INFO::Adjusting sequential tree level 1 with 2 batches
design matrix of interest not specified. Assuming a one-group experiment.
2026-03-08 16:36:13.649012 INFO::Done
2026-03-08 16:36:13.649307 INFO::Acquiring quality metrics after batch effect correction.
2026-03-08 16:36:13.65053 INFO::ASW Batch was 0.266225116756558 prior to batch effect correction and is now -0.0519200457859508 .
2026-03-08 16:36:13.650741 INFO::ASW Label was 0.523012900015634 prior to batch effect correction and is now 0.856376143318786 .
2026-03-08 16:36:13.651019 INFO::Total function execution time is  0.104331016540527  s and adjustment time is  0.0977709293365479 s ( 93.71 )
2026-03-08 16:36:13.651293 INFO::Formatting Data.
2026-03-08 16:36:13.651497 INFO::Replacing NaNs with NAs.
2026-03-08 16:36:13.651805 INFO::Removing potential empty rows and columns
2026-03-08 16:36:13.652207 INFO::Found  0  missing values.
2026-03-08 16:36:13.653727 INFO::Introduced 0 missing values due to singular proteins at batch/covariate level.
2026-03-08 16:36:13.654086 INFO::Done
2026-03-08 16:36:13.654348 INFO::Acquiring quality metrics before batch effect correction.
2026-03-08 16:36:13.655668 INFO::Starting hierarchical adjustment
2026-03-08 16:36:13.65601 INFO::Found  5  batches.
2026-03-08 16:36:13.656233 INFO::Cores argument is not defined or BPPARAM has been specified. Argument corereduction will not be used.
2026-03-08 16:36:13.65651 INFO::Using default BPPARAM
2026-03-08 16:36:13.656715 INFO::Processing subtree level 1
design matrix of interest not specified. Assuming a one-group experiment.

design matrix of interest not specified. Assuming a one-group experiment.
design matrix of interest not specified. Assuming a one-group experiment.

2026-03-08 16:36:13.730399 INFO::Adjusting the last 2 batches sequentially
2026-03-08 16:36:13.73141 INFO::Adjusting sequential tree level 1 with 2 batches
design matrix of interest not specified. Assuming a one-group experiment.
2026-03-08 16:36:13.739525 INFO::Done
2026-03-08 16:36:13.739816 INFO::Acquiring quality metrics after batch effect correction.
2026-03-08 16:36:13.741019 INFO::ASW Batch was 0.266225116756558 prior to batch effect correction and is now -0.0519200457859508 .
2026-03-08 16:36:13.741214 INFO::ASW Label was 0.523012900015634 prior to batch effect correction and is now 0.856376143318786 .
2026-03-08 16:36:13.741526 INFO::Total function execution time is  0.0902090072631836  s and adjustment time is  0.0835919380187988 s ( 92.66 )
2026-03-08 16:36:13.747229 INFO::Formatting Data.
2026-03-08 16:36:13.747479 INFO::Replacing NaNs with NAs.
2026-03-08 16:36:13.747806 INFO::Removing potential empty rows and columns
2026-03-08 16:36:13.748151 INFO::Found  0  missing values.
2026-03-08 16:36:13.749055 INFO::Introduced 0 missing values due to singular proteins at batch/covariate level.
2026-03-08 16:36:13.749232 INFO::Done
2026-03-08 16:36:13.749395 INFO::Acquiring quality metrics before batch effect correction.
2026-03-08 16:36:13.750376 INFO::Starting hierarchical adjustment
2026-03-08 16:36:13.750611 INFO::Found  2  batches.
2026-03-08 16:36:13.750792 INFO::Cores argument is not defined or BPPARAM has been specified. Argument corereduction will not be used.
2026-03-08 16:36:13.751027 INFO::Using default BPPARAM
2026-03-08 16:36:13.751196 INFO::Adjusting the last 2 batches sequentially
2026-03-08 16:36:13.751517 INFO::Adjusting sequential tree level 1 with 2 batches
design matrix of interest not specified. Assuming a one-group experiment.
2026-03-08 16:36:13.756873 INFO::Done
2026-03-08 16:36:13.757098 INFO::Acquiring quality metrics after batch effect correction.
2026-03-08 16:36:13.758067 INFO::ASW Batch was 0.771073806249737 prior to batch effect correction and is now 0.0318648713289612 .
2026-03-08 16:36:13.758264 INFO::ASW Label was 0.313076187960296 prior to batch effect correction and is now 0.894312915478667 .
2026-03-08 16:36:13.758518 INFO::Total function execution time is  0.0113110542297363  s and adjustment time is  0.00629782676696777 s ( 55.68 )
2026-03-08 16:36:13.758794 INFO::Formatting Data.
2026-03-08 16:36:13.758988 INFO::Replacing NaNs with NAs.
2026-03-08 16:36:13.759276 INFO::Removing potential empty rows and columns
2026-03-08 16:36:13.75959 INFO::Found  0  missing values.
2026-03-08 16:36:13.760452 INFO::Introduced 0 missing values due to singular proteins at batch/covariate level.
2026-03-08 16:36:13.760621 INFO::Done
2026-03-08 16:36:13.760783 INFO::Acquiring quality metrics before batch effect correction.
2026-03-08 16:36:13.761665 INFO::Starting hierarchical adjustment
2026-03-08 16:36:13.761895 INFO::Found  2  batches.
2026-03-08 16:36:13.762053 INFO::Cores argument is not defined or BPPARAM has been specified. Argument corereduction will not be used.
2026-03-08 16:36:13.762261 INFO::Using default BPPARAM
2026-03-08 16:36:13.762418 INFO::Adjusting the last 2 batches sequentially
2026-03-08 16:36:13.762668 INFO::Adjusting sequential tree level 1 with 2 batches
design matrix of interest not specified. Assuming a one-group experiment.
2026-03-08 16:36:13.767555 INFO::Done
2026-03-08 16:36:13.767764 INFO::Acquiring quality metrics after batch effect correction.
2026-03-08 16:36:13.768709 INFO::ASW Batch was 0.771073806249737 prior to batch effect correction and is now 0.0318648713289612 .
2026-03-08 16:36:13.768913 INFO::ASW Label was 0.313076187960296 prior to batch effect correction and is now 0.894312915478667 .
2026-03-08 16:36:13.769194 INFO::Total function execution time is  0.0103859901428223  s and adjustment time is  0.00569987297058105 s ( 54.88 )
2026-03-08 16:36:13.774001 INFO::Formatting Data.
2026-03-08 16:36:13.774242 INFO::Replacing NaNs with NAs.
2026-03-08 16:36:13.774515 INFO::Removing potential empty rows and columns
2026-03-08 16:36:13.774808 INFO::Found  0  missing values.
2026-03-08 16:36:13.775487 INFO::Introduced 0 missing values due to singular proteins at batch/covariate level.
2026-03-08 16:36:13.775642 INFO::Done
2026-03-08 16:36:13.7758 INFO::Acquiring quality metrics before batch effect correction.
2026-03-08 16:36:13.776366 INFO::Starting hierarchical adjustment
2026-03-08 16:36:13.776572 INFO::Found  2  batches.
2026-03-08 16:36:13.776725 INFO::Cores argument is not defined or BPPARAM has been specified. Argument corereduction will not be used.
2026-03-08 16:36:13.776911 INFO::Using default BPPARAM
2026-03-08 16:36:13.777056 INFO::Adjusting the last 2 batches sequentially
2026-03-08 16:36:13.777294 INFO::Adjusting sequential tree level 1 with 2 batches
2026-03-08 16:36:13.787708 INFO::Done
2026-03-08 16:36:13.787959 INFO::Acquiring quality metrics after batch effect correction.
2026-03-08 16:36:13.788666 INFO::ASW Batch was 0.0635988496128384 prior to batch effect correction and is now -0.0991417735614653 .
2026-03-08 16:36:13.788939 INFO::Total function execution time is  0.0149660110473633  s and adjustment time is  0.0111570358276367 s ( 74.55 )
2026-03-08 16:36:13.793598 INFO::Formatting Data.
2026-03-08 16:36:13.793829 INFO::Replacing NaNs with NAs.
2026-03-08 16:36:13.794107 INFO::Removing potential empty rows and columns
2026-03-08 16:36:13.794441 INFO::Found  0  missing values.
2026-03-08 16:36:13.794845 INFO::BERT requires at least 2 numeric values per batch/covariate level. This may reduce the number of adjustable features considerably, depending on the quantification technique.
2026-03-08 16:36:13.796577 INFO::Introduced 0 missing values due to singular proteins at batch/covariate level.
2026-03-08 16:36:13.796802 INFO::Done
2026-03-08 16:36:13.796978 INFO::Acquiring quality metrics before batch effect correction.
2026-03-08 16:36:13.798022 INFO::Starting hierarchical adjustment
2026-03-08 16:36:13.798266 INFO::Found  2  batches.
2026-03-08 16:36:13.798713 INFO::Cores argument is not defined or BPPARAM has been specified. Argument corereduction will not be used.
2026-03-08 16:36:13.798907 INFO::Using default BPPARAM
2026-03-08 16:36:13.799054 INFO::Adjusting the last 2 batches sequentially
2026-03-08 16:36:13.799366 INFO::Adjusting sequential tree level 1 with 2 batches
2026-03-08 16:36:13.804717 INFO::Done
2026-03-08 16:36:13.804916 INFO::Acquiring quality metrics after batch effect correction.
2026-03-08 16:36:13.805795 INFO::ASW Batch was 0.352538658849112 prior to batch effect correction and is now 0.000559669808065273 .
2026-03-08 16:36:13.805979 INFO::ASW Label was 0.711816045475817 prior to batch effect correction and is now 0.93002847683705 .
2026-03-08 16:36:13.806205 INFO::Total function execution time is  0.0126440525054932  s and adjustment time is  0.00649309158325195 s ( 51.35 )
2026-03-08 16:36:13.806459 INFO::Formatting Data.
2026-03-08 16:36:13.806627 INFO::Replacing NaNs with NAs.
2026-03-08 16:36:13.806876 INFO::Removing potential empty rows and columns
2026-03-08 16:36:13.807158 INFO::Found  0  missing values.
2026-03-08 16:36:13.807401 INFO::BERT requires at least 2 numeric values per batch/covariate level. This may reduce the number of adjustable features considerably, depending on the quantification technique.
2026-03-08 16:36:13.808701 INFO::Introduced 0 missing values due to singular proteins at batch/covariate level.
2026-03-08 16:36:13.808895 INFO::Done
2026-03-08 16:36:13.809051 INFO::Acquiring quality metrics before batch effect correction.
2026-03-08 16:36:13.809918 INFO::Starting hierarchical adjustment
2026-03-08 16:36:13.810142 INFO::Found  2  batches.
2026-03-08 16:36:13.810293 INFO::Cores argument is not defined or BPPARAM has been specified. Argument corereduction will not be used.
2026-03-08 16:36:13.810477 INFO::Using default BPPARAM
2026-03-08 16:36:13.810632 INFO::Adjusting the last 2 batches sequentially
2026-03-08 16:36:13.810921 INFO::Adjusting sequential tree level 1 with 2 batches
2026-03-08 16:36:13.816217 INFO::Done
2026-03-08 16:36:13.816448 INFO::Acquiring quality metrics after batch effect correction.
2026-03-08 16:36:13.817348 INFO::ASW Batch was 0.352538658849112 prior to batch effect correction and is now 0.000559669808065273 .
2026-03-08 16:36:13.817553 INFO::ASW Label was 0.711816045475817 prior to batch effect correction and is now 0.93002847683705 .
2026-03-08 16:36:13.817789 INFO::Total function execution time is  0.011340856552124  s and adjustment time is  0.00610089302062988 s ( 53.8 )
2026-03-08 16:36:13.883998 INFO::Formatting Data.
2026-03-08 16:36:13.884265 INFO::Replacing NaNs with NAs.
2026-03-08 16:36:13.884556 INFO::Removing potential empty rows and columns
2026-03-08 16:36:13.884886 INFO::Found  0  missing values.
2026-03-08 16:36:13.885775 INFO::Introduced 0 missing values due to singular proteins at batch/covariate level.
2026-03-08 16:36:13.88594 INFO::Done
2026-03-08 16:36:13.886113 INFO::Acquiring quality metrics before batch effect correction.
2026-03-08 16:36:13.886764 INFO::Starting hierarchical adjustment
2026-03-08 16:36:13.886977 INFO::Found  3  batches.
2026-03-08 16:36:13.887124 INFO::Cores argument is not defined or BPPARAM has been specified. Argument corereduction will not be used.
2026-03-08 16:36:13.887306 INFO::Using default BPPARAM
2026-03-08 16:36:13.887471 INFO::Processing subtree level 1
2026-03-08 16:36:13.9602 INFO::Adjusting the last 1 batches sequentially
2026-03-08 16:36:13.960994 INFO::Done
2026-03-08 16:36:13.961196 INFO::Acquiring quality metrics after batch effect correction.
2026-03-08 16:36:13.962103 INFO::ASW Batch was -0.089363429423104 prior to batch effect correction and is now -0.089363429423104 .
2026-03-08 16:36:13.962448 INFO::Total function execution time is  0.0784869194030762  s and adjustment time is  0.0740621089935303 s ( 94.36 )
2026-03-08 16:36:13.962761 INFO::Formatting Data.
2026-03-08 16:36:13.962939 INFO::Typecasting input to dataframe.
2026-03-08 16:36:13.963175 INFO::Replacing NaNs with NAs.
2026-03-08 16:36:13.96345 INFO::Removing potential empty rows and columns
2026-03-08 16:36:13.963789 INFO::Found  0  missing values.
2026-03-08 16:36:13.964729 INFO::Introduced 0 missing values due to singular proteins at batch/covariate level.
2026-03-08 16:36:13.964908 INFO::Done
2026-03-08 16:36:13.965074 INFO::Acquiring quality metrics before batch effect correction.
2026-03-08 16:36:13.965677 INFO::Starting hierarchical adjustment
2026-03-08 16:36:13.965884 INFO::Found  3  batches.
2026-03-08 16:36:13.966032 INFO::Cores argument is not defined or BPPARAM has been specified. Argument corereduction will not be used.
2026-03-08 16:36:13.966227 INFO::Using default BPPARAM
2026-03-08 16:36:13.966393 INFO::Processing subtree level 1
2026-03-08 16:36:14.022459 INFO::Adjusting the last 1 batches sequentially
2026-03-08 16:36:14.023398 INFO::Done
2026-03-08 16:36:14.023604 INFO::Acquiring quality metrics after batch effect correction.
2026-03-08 16:36:14.024586 INFO::ASW Batch was -0.089363429423104 prior to batch effect correction and is now -0.089363429423104 .
2026-03-08 16:36:14.024955 INFO::Total function execution time is  0.0621559619903564  s and adjustment time is  0.0575480461120605 s ( 92.59 )
2026-03-08 16:36:14.030449 INFO::Formatting Data.
2026-03-08 16:36:14.030684 INFO::Typecasting input to dataframe.
2026-03-08 16:36:14.030949 INFO::Replacing NaNs with NAs.
2026-03-08 16:36:14.031248 INFO::Removing potential empty rows and columns
2026-03-08 16:36:14.031634 INFO::Found  0  missing values.
2026-03-08 16:36:14.032517 INFO::Introduced 0 missing values due to singular proteins at batch/covariate level.
2026-03-08 16:36:14.032686 INFO::Done
2026-03-08 16:36:14.032842 INFO::Acquiring quality metrics before batch effect correction.
2026-03-08 16:36:14.033455 INFO::Starting hierarchical adjustment
2026-03-08 16:36:14.033663 INFO::Found  3  batches.
2026-03-08 16:36:14.033823 INFO::Cores argument is not defined or BPPARAM has been specified. Argument corereduction will not be used.
2026-03-08 16:36:14.034032 INFO::Using default BPPARAM
2026-03-08 16:36:14.034188 INFO::Processing subtree level 1
2026-03-08 16:36:14.092633 INFO::Adjusting the last 1 batches sequentially
2026-03-08 16:36:14.09377 INFO::Done
2026-03-08 16:36:14.093977 INFO::Acquiring quality metrics after batch effect correction.
2026-03-08 16:36:14.095277 INFO::ASW Batch was -0.0606670506443415 prior to batch effect correction and is now -0.0606670506443415 .
2026-03-08 16:36:14.095755 INFO::Total function execution time is  0.065310001373291  s and adjustment time is  0.0601449012756348 s ( 92.09 )
2026-03-08 16:36:14.178817 INFO::Formatting Data.
2026-03-08 16:36:14.179097 INFO::Replacing NaNs with NAs.
2026-03-08 16:36:14.179519 INFO::Removing potential empty rows and columns
2026-03-08 16:36:14.180457 INFO::Found  1000  missing values.
2026-03-08 16:36:14.186296 INFO::Introduced 0 missing values due to singular proteins at batch/covariate level.
2026-03-08 16:36:14.186557 INFO::Done
2026-03-08 16:36:14.186738 INFO::Acquiring quality metrics before batch effect correction.
2026-03-08 16:36:14.188756 INFO::Starting hierarchical adjustment
2026-03-08 16:36:14.189026 INFO::Found  10  batches.
2026-03-08 16:36:14.1892 INFO::Cores argument is not defined or BPPARAM has been specified. Argument corereduction will not be used.
2026-03-08 16:36:14.189445 INFO::Using default BPPARAM
2026-03-08 16:36:14.189613 INFO::Processing subtree level 1
2026-03-08 16:36:14.271546 INFO::Processing subtree level 2
2026-03-08 16:36:14.348638 INFO::Adjusting the last 1 batches sequentially
2026-03-08 16:36:14.349707 INFO::Done
2026-03-08 16:36:14.349948 INFO::Acquiring quality metrics after batch effect correction.
2026-03-08 16:36:14.35248 INFO::ASW Batch was 0.494231080290104 prior to batch effect correction and is now 0.494231080290104 .
2026-03-08 16:36:14.352724 INFO::ASW Label was 0.343541544819002 prior to batch effect correction and is now 0.343541544819002 .
2026-03-08 16:36:14.353134 INFO::Total function execution time is  0.174345016479492  s and adjustment time is  0.160732984542847 s ( 92.19 )
2026-03-08 16:36:14.353438 INFO::Formatting Data.
2026-03-08 16:36:14.353637 INFO::Replacing NaNs with NAs.
2026-03-08 16:36:14.354091 INFO::Removing potential empty rows and columns
2026-03-08 16:36:14.355258 INFO::Found  1000  missing values.
2026-03-08 16:36:14.361654 INFO::Introduced 0 missing values due to singular proteins at batch/covariate level.
2026-03-08 16:36:14.361859 INFO::Done
2026-03-08 16:36:14.362026 INFO::Acquiring quality metrics before batch effect correction.
2026-03-08 16:36:14.363913 INFO::Starting hierarchical adjustment
2026-03-08 16:36:14.364156 INFO::Found  10  batches.
2026-03-08 16:36:14.7733 INFO::Set up parallel execution backend with 2 workers
2026-03-08 16:36:14.773602 INFO::Processing subtree level 1 with 10 batches using 2 cores.
2026-03-08 16:36:15.368791 INFO::Adjusting the last 2 batches sequentially
2026-03-08 16:36:15.369311 INFO::Adjusting sequential tree level 1 with 2 batches
2026-03-08 16:36:15.374978 INFO::Done
2026-03-08 16:36:15.375182 INFO::Acquiring quality metrics after batch effect correction.
2026-03-08 16:36:15.377042 INFO::ASW Batch was 0.494231080290104 prior to batch effect correction and is now 0.494231080290104 .
2026-03-08 16:36:15.377218 INFO::ASW Label was 0.343541544819002 prior to batch effect correction and is now 0.343541544819002 .
2026-03-08 16:36:15.37745 INFO::Total function execution time is  1.02401685714722  s and adjustment time is  1.01087117195129 s ( 98.72 )
2026-03-08 16:36:15.509762 INFO::Formatting Data.
2026-03-08 16:36:15.510037 INFO::Replacing NaNs with NAs.
2026-03-08 16:36:15.510363 INFO::Removing potential empty rows and columns
2026-03-08 16:36:15.510816 INFO::Found  0  missing values.
2026-03-08 16:36:15.512192 INFO::Introduced 0 missing values due to singular proteins at batch/covariate level.
2026-03-08 16:36:15.512394 INFO::Done
2026-03-08 16:36:15.512575 INFO::Acquiring quality metrics before batch effect correction.
2026-03-08 16:36:15.513565 INFO::Starting hierarchical adjustment
2026-03-08 16:36:15.513829 INFO::Found  3  batches.
2026-03-08 16:36:15.514024 INFO::Cores argument is not defined or BPPARAM has been specified. Argument corereduction will not be used.
2026-03-08 16:36:15.514264 INFO::Using default BPPARAM
2026-03-08 16:36:15.514453 INFO::Processing subtree level 1
2026-03-08 16:36:15.590652 INFO::Adjusting the last 1 batches sequentially
2026-03-08 16:36:15.591872 INFO::Done
2026-03-08 16:36:15.592118 INFO::Acquiring quality metrics after batch effect correction.
2026-03-08 16:36:15.593556 INFO::ASW Batch was 0.208503297057673 prior to batch effect correction and is now -0.169058140517282 .
2026-03-08 16:36:15.593801 INFO::ASW Label was -0.144859419015057 prior to batch effect correction and is now 0.0520152736705159 .
2026-03-08 16:36:15.59424 INFO::Total function execution time is  0.0844821929931641  s and adjustment time is  0.0780899524688721 s ( 92.43 )
2026-03-08 16:36:15.650161 INFO::Formatting Data.
2026-03-08 16:36:15.650512 INFO::Replacing NaNs with NAs.
2026-03-08 16:36:15.650839 INFO::Removing potential empty rows and columns
2026-03-08 16:36:15.651244 INFO::Found  2  missing values.
2026-03-08 16:36:15.652221 INFO::Introduced 1 missing values due to singular proteins at batch/covariate level.
2026-03-08 16:36:15.652395 INFO::Done
2026-03-08 16:36:15.663718 INFO::Found NA in Reference column
2026-03-08 16:36:15.667651 INFO::Require at least two references per batch.
2026-03-08 16:36:15.67603 INFO::Formatting Data.
2026-03-08 16:36:15.676275 INFO::Recognized SummarizedExperiment
2026-03-08 16:36:15.676454 INFO::Typecasting input to dataframe.
2026-03-08 16:36:15.68009 INFO::Replacing NaNs with NAs.
2026-03-08 16:36:15.680465 INFO::Removing potential empty rows and columns
2026-03-08 16:36:15.681734 INFO::Found  0  missing values.
2026-03-08 16:36:15.68416 INFO::Introduced 0 missing values due to singular proteins at batch/covariate level.
2026-03-08 16:36:15.68433 INFO::Done
2026-03-08 16:36:15.689553 INFO::Formatting Data.
2026-03-08 16:36:15.689761 INFO::Recognized SummarizedExperiment
2026-03-08 16:36:15.689927 INFO::Typecasting input to dataframe.
2026-03-08 16:36:15.69572 INFO::Replacing NaNs with NAs.
2026-03-08 16:36:15.696177 INFO::Removing potential empty rows and columns
2026-03-08 16:36:15.697401 INFO::Found  0  missing values.
2026-03-08 16:36:15.701104 INFO::Introduced 0 missing values due to singular proteins at batch/covariate level.
2026-03-08 16:36:15.701291 INFO::Done
2026-03-08 16:36:15.706348 INFO::Formatting Data.
2026-03-08 16:36:15.706547 INFO::Recognized SummarizedExperiment
2026-03-08 16:36:15.706706 INFO::Typecasting input to dataframe.
2026-03-08 16:36:15.711964 INFO::Replacing NaNs with NAs.
2026-03-08 16:36:15.712284 INFO::Removing potential empty rows and columns
2026-03-08 16:36:15.712622 INFO::Found  0  missing values.
2026-03-08 16:36:15.712932 INFO::BERT requires at least 2 numeric values per batch/covariate level. This may reduce the number of adjustable features considerably, depending on the quantification technique.
2026-03-08 16:36:15.714298 INFO::Introduced 0 missing values due to singular proteins at batch/covariate level.
2026-03-08 16:36:15.714466 INFO::Done
2026-03-08 16:36:15.718684 INFO::Formatting Data.
2026-03-08 16:36:15.718952 INFO::Replacing NaNs with NAs.
2026-03-08 16:36:15.71923 INFO::Removing potential empty rows and columns
2026-03-08 16:36:15.719537 INFO::Found  0  missing values.
2026-03-08 16:36:15.72042 INFO::Introduced 0 missing values due to singular proteins at batch/covariate level.
2026-03-08 16:36:15.72059 INFO::Done
2026-03-08 16:36:15.72483 INFO::Formatting Data.
2026-03-08 16:36:15.725092 INFO::Replacing NaNs with NAs.
2026-03-08 16:36:15.725361 INFO::Removing potential empty rows and columns
2026-03-08 16:36:15.725696 INFO::Found  0  missing values.
2026-03-08 16:36:15.726654 INFO::Introduced 0 missing values due to singular proteins at batch/covariate level.
2026-03-08 16:36:15.726843 INFO::Done
2026-03-08 16:36:15.739051 INFO::Formatting Data.
2026-03-08 16:36:15.739356 INFO::Replacing NaNs with NAs.
2026-03-08 16:36:15.739702 INFO::Removing potential empty rows and columns
2026-03-08 16:36:15.740093 INFO::Found  1  missing values.
2026-03-08 16:36:15.740949 INFO::Introduced 0 missing values due to singular proteins at batch/covariate level.
2026-03-08 16:36:15.741126 INFO::Done
2026-03-08 16:36:15.748874 INFO::Formatting Data.
2026-03-08 16:36:15.74919 INFO::Replacing NaNs with NAs.
2026-03-08 16:36:15.7498 INFO::Removing potential empty rows and columns
2026-03-08 16:36:15.750269 INFO::Found  2  missing values.
2026-03-08 16:36:15.750621 INFO::BERT requires at least 2 numeric values per batch/covariate level. This may reduce the number of adjustable features considerably, depending on the quantification technique.
2026-03-08 16:36:15.751417 INFO::Introduced 4 missing values due to singular proteins at batch/covariate level.
2026-03-08 16:36:15.751593 INFO::Done
2026-03-08 16:36:15.756256 INFO::Formatting Data.
2026-03-08 16:36:15.756564 INFO::Replacing NaNs with NAs.
2026-03-08 16:36:15.756871 INFO::Removing potential empty rows and columns
2026-03-08 16:36:15.757194 INFO::Found  2  missing values.
2026-03-08 16:36:15.757747 INFO::Introduced 0 missing values due to singular proteins at batch/covariate level.
2026-03-08 16:36:15.757917 INFO::Done
2026-03-08 16:36:15.762266 INFO::Formatting Data.
2026-03-08 16:36:15.762524 INFO::Typecasting input to dataframe.
2026-03-08 16:36:15.76281 INFO::Replacing NaNs with NAs.
2026-03-08 16:36:15.763099 INFO::Removing potential empty rows and columns
2026-03-08 16:36:15.763441 INFO::Found  0  missing values.
2026-03-08 16:36:15.764371 INFO::Introduced 0 missing values due to singular proteins at batch/covariate level.
2026-03-08 16:36:15.764564 INFO::Done
[ FAIL 0 | WARN 0 | SKIP 0 | PASS 134 ]
> 
> proc.time()
   user  system elapsed 
  6.705   2.040   8.872 

Example timings

BERT.Rcheck/BERT-Ex.timings

nameusersystemelapsed
BERT9.2910.4366.878
compute_asw0.0090.0010.013
count_existing0.0050.0000.006
generate_data_covariables0.0050.0010.005
generate_dataset0.0040.0010.005