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R version 3.5.1 Patched (2018-07-24 r75005) -- "Feather Spray"
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> require(trena) || stop("unable to load trena Package")
Loading required package: trena
Loading required package: glmnet
Loading required package: Matrix
Loading required package: foreach
Loaded glmnet 2.0-16
Loading required package: MotifDb
Loading required package: BiocGenerics
Loading required package: parallel
Attaching package: 'BiocGenerics'
The following objects are masked from 'package:parallel':
clusterApply, clusterApplyLB, clusterCall, clusterEvalQ,
clusterExport, clusterMap, parApply, parCapply, parLapply,
parLapplyLB, parRapply, parSapply, parSapplyLB
The following objects are masked from 'package:Matrix':
colMeans, colSums, rowMeans, rowSums, which
The following objects are masked from 'package:stats':
IQR, mad, sd, var, xtabs
The following objects are masked from 'package:base':
Filter, Find, Map, Position, Reduce, anyDuplicated, append,
as.data.frame, basename, cbind, colMeans, colSums, colnames,
dirname, do.call, duplicated, eval, evalq, get, grep, grepl,
intersect, is.unsorted, lapply, lengths, mapply, match, mget,
order, paste, pmax, pmax.int, pmin, pmin.int, rank, rbind,
rowMeans, rowSums, rownames, sapply, setdiff, sort, table, tapply,
union, unique, unsplit, which, which.max, which.min
Loading required package: S4Vectors
Loading required package: stats4
Attaching package: 'S4Vectors'
The following object is masked from 'package:Matrix':
expand
The following object is masked from 'package:base':
expand.grid
Loading required package: IRanges
Attaching package: 'IRanges'
The following object is masked from 'package:grDevices':
windows
Loading required package: Biostrings
Loading required package: XVector
Attaching package: 'Biostrings'
The following object is masked from 'package:base':
strsplit
See system.file("LICENSE", package="MotifDb") for use restrictions.
[1] TRUE
> BiocGenerics:::testPackage('trena')
[1] --- test_BayesSpikeSolverConstructor
[1] --- test_ampAD.mef2c.154tfs.278samples.bayesSpike
[1] --- test_nOrderings
[1] --- test_BayesSpikeSolverConstructor
[1] --- test_ampAD.mef2c.154tfs.278samples.bayesSpike
[1] --- test_nOrderings
[1] --- test_CandidateFilter
[1] --- test_CandidateFilter
[1] --- test_EnsembleSolverConstructor
[1] --- test_ampAD.mef2c.154tfs.278samples.ensemble
[1] --- test_selectedSolversOnly
[1] --- test_pcaError
[1] --- test_getSolverNames
[1] --- test_oneSolver
[1] --- test_invalidSolvers
[1] --- test_EnsembleSolverConstructor
Warning in Solver(mtx.assay = mtx.assay, targetGene = targetGene, candidateRegulators = candidateRegulators, :
Target gene mean expression is in the bottom 10% of all genes in the assay matrix
[1] --- test_ampAD.mef2c.154tfs.278samples.ensemble
[1] --- test_getSolverNames
[1] --- test_invalidSolvers
[1] --- test_oneSolver
[1] --- test_pcaError
[1] --- test_selectedSolversOnly
[1] --- test_FootprintFilter.byRegion
[1] --- test_FootprintFilter.byTwoRegions
[1] --- test_FootprintFilter.byRegion
[1] --- test_FootprintFilter.byTwoRegions
Loading required package: DBI
[1] --- test_parseDatabaseUri
[1] --- test_constructor
[1] --- test_getGtfGeneBioTypes
[1] --- test_getGtfMoleculeTypes
[1] --- test_getChromLoc
[1] --- test_getGenePromoterRegion
[1] --- test_getFootprintsInRegion
[1] --- test_getFootprintsInRegionWithVariants
[1] --- test_getFootprintsForGene
[1] --- test_constructor
[1] --- test_getChromLoc
[1] --- test_getFootprintsForGene
[1] --- test_getFootprintsInRegion
[1] --- test_getFootprintsInRegionWithVariants
Warning: call dbDisconnect() when finished working with a connection
[1] --- test_getGenePromoterRegion
[1] --- test_getGtfGeneBioTypes
[1] --- test_getGtfMoleculeTypes
[1] --- test_parseDatabaseUri
[1] --- test_directMode
Loading required package: org.Hs.eg.db
Loading required package: AnnotationDbi
Loading required package: Biobase
Welcome to Bioconductor
Vignettes contain introductory material; view with
'browseVignettes()'. To cite Bioconductor, see
'citation("Biobase")', and for packages 'citation("pkgname")'.
[1] --- test_directMode
[1] --- test_LassoPvSolverConstructor
Warning in Solver(mtx.assay = mtx.assay, quiet = quiet, targetGene = targetGene, :
Target gene mean expression is in the bottom 10% of all genes in the assay matrix
[1] --- test_ampAD.mef2c.154tfs.278samples.lassopv
[1] --- test_LassoPvSolverConstructor
Warning in Solver(mtx.assay = mtx.assay, quiet = quiet, targetGene = targetGene, :
Target gene mean expression is in the bottom 10% of all genes in the assay matrix
[1] --- test_ampAD.mef2c.154tfs.278samples.lassopv
[1] --- test_LassoSolverConstructor
Warning in Solver(mtx.assay = mtx.assay, quiet = quiet, targetGene = targetGene, :
Target gene mean expression is in the bottom 10% of all genes in the assay matrix
[1] --- test_developAndFitDummyTestData
[1] --- test_fitDummyData
[1] --- test_ampAD.mef2c.154tfs.278samples.lasso
[1] --- test_alpha.lasso
[1] --- test_lambda.lasso
[1] --- test_keep.metrics.lasso
[1] --- test_scalePredictorPenalties.lasso
Warning in Solver(mtx.assay = mtx.assay, quiet = quiet, targetGene = targetGene, :
Target gene mean expression is in the bottom 10% of all genes in the assay matrix
[1] --- test_LassoSolverConstructor
Warning in Solver(mtx.assay = mtx.assay, quiet = quiet, targetGene = targetGene, :
Target gene mean expression is in the bottom 10% of all genes in the assay matrix
[1] --- test_alpha.lasso
[1] --- test_ampAD.mef2c.154tfs.278samples.lasso
[1] --- test_developAndFitDummyTestData
[1] --- test_fitDummyData
[1] --- test_keep.metrics.lasso
[1] --- test_lambda.lasso
[1] --- test_scalePredictorPenalties.lasso
Warning in Solver(mtx.assay = mtx.assay, quiet = quiet, targetGene = targetGene, :
Target gene mean expression is in the bottom 10% of all genes in the assay matrix
[1] --- test_.getScoredMotifs
[1] --- test_.injectSnp
[1] --- test_basicConstructor
[1] --- test_bugInStartEndOfMinusStrandHits
[1] --- test_findMatchesByChromosomalRegion
[1] best$seq: ACCAGCATGCAAATTAGACAA
[1] --- test_findMatchesByChromosomalRegion.twoAlternateAlleles
[1] --- test_findMatchesByChromosomalRegion_contrastReferenceWithVariant
[1] --- test_findMatchesByMultipleChromosomalRegions
[1] --- test_getSequence
[1] --- test_getSequenceWithVariants
[1] --- test_noMatch
[1] --- test_PearsonSolverConstructor
Warning in Solver(mtx.assay = mtx.assay, quiet = quiet, targetGene = targetGene, :
Target gene mean expression is in the bottom 10% of all genes in the assay matrix
[1] --- test_ampAD.mef2c.154tfs.278samples.pearson
[1] --- test_PearsonSolverConstructor
Warning in Solver(mtx.assay = mtx.assay, quiet = quiet, targetGene = targetGene, :
Target gene mean expression is in the bottom 10% of all genes in the assay matrix
[1] --- test_ampAD.mef2c.154tfs.278samples.pearson
[1] --- test_RandomForestSolverConstructor
[1] --- test_RandomForestSolverFewCandidates
[1] --- test_ampAD.mef2c.154tfs.278samples.randomForest
[1] --- test_RandomForestSolverConstructor
[1] --- test_RandomForestSolverFewCandidates
[1] --- test_ampAD.mef2c.154tfs.278samples.randomForest
[1] --- test_RidgeSolverConstructor
Warning in Solver(mtx.assay = mtx.assay, quiet = quiet, targetGene = targetGene, :
Target gene mean expression is in the bottom 10% of all genes in the assay matrix
[1] --- test_ampAD.mef2c.154tfs.278samples.ridge
[1] --- test_alpha.ridge
[1] --- test_lambda.ridge
[1] --- test_keep.metrics.ridge
[1] --- test_RidgeSolverConstructor
Warning in Solver(mtx.assay = mtx.assay, quiet = quiet, targetGene = targetGene, :
Target gene mean expression is in the bottom 10% of all genes in the assay matrix
[1] --- test_alpha.ridge
[1] --- test_ampAD.mef2c.154tfs.278samples.ridge
[1] --- test_keep.metrics.ridge
[1] --- test_lambda.ridge
[1] --- test_getAssayData
Warning in Solver(mtx, "gene1", c("gene2", "gene3")) :
Target gene mean expression is in the bottom 10% of all genes in the assay matrix
[1] --- test_getTarget
[1] --- test_getRegulators
[1] --- test_eliminateSelfTFs
[1] --- test_MatrixWarnings
[1] --- test_TargetAndRegulatorWarnings
[1] --- test_MatrixWarnings
[1] --- test_TargetAndRegulatorWarnings
[1] --- test_eliminateSelfTFs
[1] --- test_getAssayData
[1] --- test_getRegulators
[1] --- test_getTarget
[1] --- test_SpearmanSolverConstructor
Warning in Solver(mtx.assay = mtx.assay, quiet = quiet, targetGene = targetGene, :
Target gene mean expression is in the bottom 10% of all genes in the assay matrix
[1] --- test_ampAD.mef2c.154tfs.278samples.spearman
[1] --- test_SpearmanSolverConstructor
Warning in Solver(mtx.assay = mtx.assay, quiet = quiet, targetGene = targetGene, :
Target gene mean expression is in the bottom 10% of all genes in the assay matrix
[1] --- test_ampAD.mef2c.154tfs.278samples.spearman
[1] --- test_SqrtLassoSolverConstructor
[1] --- test_ampAD.mef2c.154tfs.278samples.sqrtlasso
See system.file("LICENSE", package="MotifDb") for use restrictions.
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[1] --- test_lambda.sqrtlasso
[1] --- test_nCores.sqrtlasso
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<environment: namespace:RSQLite>
con_
con_
con_
con_
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<environment: namespace:RSQLite>
<environment: namespace:RSQLite>
con_
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con_
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<environment: namespace:RSQLite>
<environment: namespace:RSQLite>
<environment: namespace:RSQLite>
<environment: namespace:RSQLite>
con_
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<environment: namespace:RSQLite>
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<environment: namespace:RSQLite>
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con_
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<environment: namespace:RSQLite>
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con_
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<environment: namespace:RSQLite>
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con_
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con_
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<environment: namespace:RSQLite>
<environment: namespace:RSQLite>
con_
<environment: namespace:RSQLite>
con_
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con_
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<environment: namespace:RSQLite>
con_
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<environment: namespace:RSQLite>
con_
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<environment: namespace:RSQLite>
<environment: namespace:RSQLite>
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[1] --- test_SqrtLassoSolverConstructor
[1] --- test_ampAD.mef2c.154tfs.278samples.sqrtlasso
See system.file("LICENSE", package="MotifDb") for use restrictions.
<environment: 0x000000000518d1c0>
lambda
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stop.on.error
stop.immediate
as.error
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<environment: 0x000000000518b630>
...
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[3]
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See system.file("LICENSE", package="MotifDb") for use restrictions.
<environment: 0x000000000518d240>
lambda
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stop.on.error
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<environment: 0x000000000518b6b0>
...
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See system.file("LICENSE", package="MotifDb") for use restrictions.
<environment: 0x000000000518d3f0>
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<environment: 0x000000000518b860>
...
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[3]
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See system.file("LICENSE", package="MotifDb") for use restrictions.
<environment: 0x000000000518d218>
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<environment: 0x000000000518b688>
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<environment: namespace:RSQLite>
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[1] --- test_lambda.sqrtlasso
[1] --- test_nCores.sqrtlasso
See system.file("LICENSE", package="MotifDb") for use restrictions.
<environment: 0x000000000518d218>
lambda
log
stop.on.error
stop.immediate
as.error
timeout
<environment: 0x000000000518b688>
...
class
class
class
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class
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names
[3]
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See system.file("LICENSE", package="MotifDb") for use restrictions.
<environment: 0x000000000518d218>
lambda
log
stop.on.error
stop.immediate
as.error
timeout
<environment: 0x000000000518b688>
...
class
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names
[3]
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See system.file("LICENSE", package="MotifDb") for use restrictions.
<environment: 0x000000000518d2e8>
lambda
log
stop.on.error
stop.immediate
as.error
timeout
<environment: 0x000000000518b758>
...
class
class
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class
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names
[3]
names
names
See system.file("LICENSE", package="MotifDb") for use restrictions.
<environment: 0x000000000518d288>
lambda
log
stop.on.error
stop.immediate
as.error
timeout
<environment: 0x000000000518b6f8>
...
class
class
class
class
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names
[3]
names
names
See system.file("LICENSE", package="MotifDb") for use restrictions.
<environment: 0x000000000518d288>
lambda
log
stop.on.error
stop.immediate
as.error
timeout
<environment: 0x000000000518b6f8>
...
class
class
class
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class
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names
[3]
names
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See system.file("LICENSE", package="MotifDb") for use restrictions.
<environment: 0x000000000518d288>
lambda
log
stop.on.error
stop.immediate
as.error
timeout
<environment: 0x000000000518b6f8>
...
class
class
class
class
class
class
names
[3]
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names
See system.file("LICENSE", package="MotifDb") for use restrictions.
<environment: 0x000000000518d288>
lambda
log
stop.on.error
stop.immediate
as.error
timeout
<environment: 0x000000000518b6f8>
...
class
class
class
class
class
class
names
[3]
names
names
See system.file("LICENSE", package="MotifDb") for use restrictions.
<environment: 0x000000000518d1c0>
lambda
log
stop.on.error
stop.immediate
as.error
timeout
<environment: 0x000000000518b630>
...
class
class
class
class
class
class
names
[3]
names
names
See system.file("LICENSE", package="MotifDb") for use restrictions.
<environment: 0x000000000518d288>
lambda
log
stop.on.error
stop.immediate
as.error
timeout
<environment: 0x000000000518b6f8>
...
class
class
class
class
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class
names
[3]
names
names
See system.file("LICENSE", package="MotifDb") for use restrictions.
<environment: 0x000000000518d3f0>
lambda
log
stop.on.error
stop.immediate
as.error
timeout
<environment: 0x000000000518b860>
...
class
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[3]
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See system.file("LICENSE", package="MotifDb") for use restrictions.
<environment: 0x000000000518d288>
lambda
log
stop.on.error
stop.immediate
as.error
timeout
<environment: 0x000000000518b6f8>
...
class
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[3]
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See system.file("LICENSE", package="MotifDb") for use restrictions.
<environment: 0x000000000518d368>
lambda
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stop.on.error
stop.immediate
as.error
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<environment: 0x000000000518b7d8>
...
class
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[3]
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See system.file("LICENSE", package="MotifDb") for use restrictions.
<environment: 0x000000000518d218>
lambda
log
stop.on.error
stop.immediate
as.error
timeout
<environment: 0x000000000518b688>
...
class
class
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[3]
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See system.file("LICENSE", package="MotifDb") for use restrictions.
<environment: 0x000000000518d240>
lambda
log
stop.on.error
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as.error
timeout
<environment: 0x000000000518b6b0>
...
class
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[3]
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See system.file("LICENSE", package="MotifDb") for use restrictions.
<environment: 0x000000000518d218>
lambda
log
stop.on.error
stop.immediate
as.error
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<environment: 0x000000000518b688>
...
class
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[3]
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See system.file("LICENSE", package="MotifDb") for use restrictions.
<environment: 0x000000000518d218>
lambda
log
stop.on.error
stop.immediate
as.error
timeout
<environment: 0x000000000518b688>
...
class
class
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[3]
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See system.file("LICENSE", package="MotifDb") for use restrictions.
<environment: 0x000000000518d288>
lambda
log
stop.on.error
stop.immediate
as.error
timeout
<environment: 0x000000000518b6f8>
...
class
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[3]
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See system.file("LICENSE", package="MotifDb") for use restrictions.
<environment: 0x000000000518d218>
lambda
log
stop.on.error
stop.immediate
as.error
timeout
<environment: 0x000000000518b688>
...
class
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[3]
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See system.file("LICENSE", package="MotifDb") for use restrictions.
<environment: 0x000000000518d288>
lambda
log
stop.on.error
stop.immediate
as.error
timeout
<environment: 0x000000000518b6f8>
...
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<environment: namespace:base>
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[1] --- test_basicConstructor
[1] --- test_getRegulatoryRegions_oneFootprintSource
[1] calling footprintFilter with source = 'sqlite://C:/Users/biocbuild/bbs-3.7-bioc/R/library/trena/extdata/mef2c.neigborhood.hg38.footprints.db', span: 2001
[1] --- test_getRegulatoryRegions_encodeDHS
[1] calling HumanDHSFilter, span: 5
[1] calling HumanDHSFilter, span: 201
[1] --- test_getRegulatoryRegions_twoFootprintSources
[1] calling footprintFilter with source = 'sqlite://C:/Users/biocbuild/bbs-3.7-bioc/R/library/trena/extdata/mef2c.neigborhood.hg38.footprints.db', span: 2001
[1] calling footprintFilter with source = 'sqlite://C:/Users/biocbuild/bbs-3.7-bioc/R/library/trena/extdata/mef2c.neigborhood.hg38.footprints.db', span: 2001
[1] --- test_createGeneModel
[1] --- test_getProximalPromoterHuman
[1] --- test_getProximalPromoterMouse
[1] --- test_assessSnp
[1] error, unrecognized variant name: 'rsBogus'
[1] --- test_assessSnp_allTypesWithDeltas
[1] --- test_basicConstructor
[1] --- test_createGeneModel
[1] --- test_getProximalPromoterHuman
[1] --- test_getProximalPromoterMouse
[1] --- test_getRegulatoryRegions_encodeDHS
[1] calling HumanDHSFilter, span: 5
[1] calling HumanDHSFilter, span: 201
[1] --- test_getRegulatoryRegions_oneFootprintSource
[1] calling footprintFilter with source = 'sqlite://C:/Users/biocbuild/bbs-3.7-bioc/R/library/trena/extdata/mef2c.neigborhood.hg38.footprints.db', span: 2001
[1] --- test_getRegulatoryRegions_twoFootprintSources
[1] calling footprintFilter with source = 'sqlite://C:/Users/biocbuild/bbs-3.7-bioc/R/library/trena/extdata/mef2c.neigborhood.hg38.footprints.db', span: 2001
[1] calling footprintFilter with source = 'sqlite://C:/Users/biocbuild/bbs-3.7-bioc/R/library/trena/extdata/mef2c.neigborhood.hg38.footprints.db', span: 2001
[1] --- test_VarianceFilter
[1] --- test_VarianceFilter
RUNIT TEST PROTOCOL -- Wed Oct 17 05:40:12 2018
***********************************************
Number of test functions: 85
Number of errors: 0
Number of failures: 0
1 Test Suite :
trena RUnit Tests - 85 test functions, 0 errors, 0 failures
Number of test functions: 85
Number of errors: 0
Number of failures: 0
Warning messages:
1: In Solver(mtx.assay = mtx.assay, targetGene = targetGene, candidateRegulators = candidateRegulators, :
Target gene mean expression is in the bottom 10% of all genes in the assay matrix
2: In Solver(mtx.assay = mtx.assay, targetGene = targetGene, candidateRegulators = candidateRegulators, :
Target gene mean expression is in the bottom 10% of all genes in the assay matrix
3: In Solver(mtx.assay = mtx.assay, targetGene = targetGene, candidateRegulators = candidateRegulators, :
Target gene mean expression is in the bottom 10% of all genes in the assay matrix
>
> proc.time()
user system elapsed
356.01 18.93 1079.06