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BioC 3.3: CHECK report for VariantAnnotation on morelia

This page was generated on 2015-10-22 17:53:04 -0400 (Thu, 22 Oct 2015).

Package 1082/1104HostnameOS / ArchINSTALLBUILDCHECKBUILD BIN
VariantAnnotation 1.17.0
Valerie Obenchain
Snapshot Date: 2015-10-21 20:20:05 -0400 (Wed, 21 Oct 2015)
URL: https://hedgehog.fhcrc.org/bioconductor/trunk/madman/Rpacks/VariantAnnotation
Last Changed Rev: 109592 / Revision: 109826
Last Changed Date: 2015-10-13 15:59:53 -0400 (Tue, 13 Oct 2015)
linux2.bioconductor.org Linux (Ubuntu 14.04.2 LTS) / x86_64  OK  OK  ERROR 
windows2.bioconductor.org Windows Server 2012 R2 Enterprise SP1 (64-bit) / x64  OK  OK  ERROR  OK 
morelia Mac OS X Mavericks (10.9.5) / x86_64  OK  OK [ ERROR ] OK 

Summary

Package: VariantAnnotation
Version: 1.17.0
Command: /Library/Frameworks/R.framework/Versions/Current/Resources/bin/R CMD check --no-vignettes --timings VariantAnnotation_1.17.0.tar.gz
StartedAt: 2015-10-22 12:18:46 -0400 (Thu, 22 Oct 2015)
EndedAt: 2015-10-22 12:24:38 -0400 (Thu, 22 Oct 2015)
EllapsedTime: 352.4 seconds
RetCode: 1
Status:  ERROR 
CheckDir: VariantAnnotation.Rcheck
Warnings: NA

Command output

##############################################################################
##############################################################################
###
### Running command:
###
###   /Library/Frameworks/R.framework/Versions/Current/Resources/bin/R CMD check --no-vignettes --timings VariantAnnotation_1.17.0.tar.gz
###
##############################################################################
##############################################################################


* using log directory ‘/Users/biocbuild/bbs-3.3-bioc/meat/VariantAnnotation.Rcheck’
* using R Under development (unstable) (2015-10-08 r69496)
* using platform: x86_64-apple-darwin13.4.0 (64-bit)
* using session charset: UTF-8
* using option ‘--no-vignettes’
* checking for file ‘VariantAnnotation/DESCRIPTION’ ... OK
* checking extension type ... Package
* this is package ‘VariantAnnotation’ version ‘1.17.0’
* checking package namespace information ... OK
* checking package dependencies ... OK
* checking if this is a source package ... OK
* checking if there is a namespace ... OK
* checking for hidden files and directories ... OK
* checking for portable file names ... OK
* checking for sufficient/correct file permissions ... OK
* checking whether package ‘VariantAnnotation’ can be installed ... [17s/18s] OK
* checking installed package size ... OK
* checking package directory ... OK
* checking ‘build’ directory ... OK
* checking DESCRIPTION meta-information ... NOTE
Malformed Description field: should contain one or more complete sentences.
* checking top-level files ... OK
* checking for left-over files ... OK
* checking index information ... OK
* checking package subdirectories ... OK
* checking R files for non-ASCII characters ... OK
* checking R files for syntax errors ... OK
* checking whether the package can be loaded ... OK
* checking whether the package can be loaded with stated dependencies ... OK
* checking whether the package can be unloaded cleanly ... OK
* checking whether the namespace can be loaded with stated dependencies ... OK
* checking whether the namespace can be unloaded cleanly ... OK
* checking dependencies in R code ... NOTE
'library' or 'require' call to ‘snpStats’ in package code.
  Please use :: or requireNamespace() instead.
  See section 'Suggested packages' in the 'Writing R Extensions' manual.
':::' call which should be '::': ‘DBI:::dbListFields’
  See the note in ?`:::` about the use of this operator.
Unexported objects imported by ':::' calls:
  ‘BiocGenerics:::replaceSlots’ ‘BiocGenerics:::testPackage’
  ‘GenomicRanges:::.bind.arrays’ ‘GenomicRanges:::.cbind.DataFrame’
  ‘IRanges:::.expandByColumnSet’ ‘Rsamtools:::.RsamtoolsFile’
  ‘Rsamtools:::.RsamtoolsFileList’ ‘Rsamtools:::.io_check_exists’
  ‘S4Vectors:::labeledLine’ ‘S4Vectors:::recycleVector’
  ‘S4Vectors:::selectSome’
  ‘SummarizedExperiment:::.SummarizedExperiment.charbound’
  See the note in ?`:::` about the use of this operator.
* checking S3 generic/method consistency ... OK
* checking replacement functions ... OK
* checking foreign function calls ... OK
* checking R code for possible problems ... NOTE
.predictCoding: no visible global function definition for
  ‘transcriptsBy’
.predictCodingGRangesList: no visible binding for global variable
  ‘GENETIC_CODE’
VRangesForMatching: no visible binding for global variable ‘REF’
VRangesForMatching: no visible binding for global variable ‘ALT’
probabilityToSnpMatrix: no visible global function definition for
  ‘post2g’
locateVariants,GRanges-TxDb-IntergenicVariants: no visible global
  function definition for ‘transcriptsBy’
locateVariants,GRanges-TxDb-IntronVariants: no visible global function
  definition for ‘intronsByTranscript’
locateVariants,GRanges-TxDb-SpliceSiteVariants: no visible global
  function definition for ‘intronsByTranscript’
summarizeVariants,TxDb-VCF-IntronVariants: no visible global function
  definition for ‘intronsByTranscript’
summarizeVariants,TxDb-VCF-SpliceSiteVariants: no visible global
  function definition for ‘intronsByTranscript’
Undefined global functions or variables:
  ALT GENETIC_CODE REF intronsByTranscript post2g transcriptsBy
* checking Rd files ... OK
* checking Rd metadata ... OK
* checking Rd cross-references ... OK
* checking for missing documentation entries ... OK
* checking for code/documentation mismatches ... OK
* checking Rd \usage sections ... OK
* checking Rd contents ... OK
* checking for unstated dependencies in examples ... OK
* checking line endings in C/C++/Fortran sources/headers ... OK
* checking line endings in Makefiles ... OK
* checking compilation flags in Makevars ... OK
* checking for GNU extensions in Makefiles ... OK
* checking for portable use of $(BLAS_LIBS) and $(LAPACK_LIBS) ... OK
* checking compiled code ... NOTE
File ‘VariantAnnotation/libs/VariantAnnotation.so’:
  Found non-API call to R: ‘getConnection’

Compiled code should not call non-API entry points in R.

See ‘Writing portable packages’ in the ‘Writing R Extensions’ manual.
* checking sizes of PDF files under ‘inst/doc’ ... OK
* checking installed files from ‘inst/doc’ ... OK
* checking files in ‘vignettes’ ... OK
* checking examples ... ERROR
Running examples in ‘VariantAnnotation-Ex.R’ failed
The error most likely occurred in:

> base::assign(".ptime", proc.time(), pos = "CheckExEnv")
> ### Name: isSNV
> ### Title: Identification of genomic variant types.
> ### Aliases: isSNV isInsertion isDeletion isIndel isDelins isTransition
> ###   isSubstitution isSNV,ExpandedVCF-method isSNV,CollapsedVCF-method
> ###   isInsertion,ExpandedVCF-method isInsertion,CollapsedVCF-method
> ###   isDeletion,ExpandedVCF-method isDeletion,CollapsedVCF-method
> ###   isIndel,ExpandedVCF-method isIndel,CollapsedVCF-method
> ###   isDelins,ExpandedVCF-method isDelins,CollapsedVCF-method
> ###   isSubstitution,ExpandedVCF-method isSubstitution,CollapsedVCF-method
> ###   isTransition,ExpandedVCF-method isTransition,CollapsedVCF-method
> ###   isSNV,VRanges-method isInsertion,VRanges-method
> ###   isDeletion,VRanges-method isIndel,VRanges-method
> ###   isDelins,VRanges-method isSubstitution,VRanges-method
> ###   isTransition,VRanges-method
> ### Keywords: methods
> 
> ### ** Examples
> 
>   fl <- system.file("extdata", "ex2.vcf", package="VariantAnnotation")
>   ## ---------------------------------------------------------------------
>   ## VCF objects 
>   ## ---------------------------------------------------------------------
>   vcf <- readVcf(fl, "hg19")
>   DataFrame(ref(vcf), alt(vcf))
DataFrame with 5 rows and 2 columns
        ref.vcf.           alt.vcf.
  <DNAStringSet> <DNAStringSetList>
1              G                  A
2              T                  A
3              A                G,T
4              T                   
5            GTC             G,GTCT
> 
>   ## This vcf has transitions in row 2 and 3. When 'singleAltOnly=TRUE' 
>   ## only the row 2 variant is identified:
>   isTransition(vcf)
[1]  TRUE FALSE FALSE FALSE FALSE
> 
>   ## Both row 2 and 3 are identified when 'singleAltOnly=FALSE':
>   isTransition(vcf, singleAltOnly=FALSE)
[1]  TRUE FALSE  TRUE FALSE FALSE
> 
>   ## Expand the CollapsedVCF to ExpandedVCF
>   evcf <- expand(vcf)
>  
>   ## All ref / alt pairs are now expanded and there is no need to 
>   ## use 'singleAltOnly'. The return length is now 7 instead of 5:
>   transition <- isTransition(evcf)
>   transition
[1]  TRUE FALSE  TRUE FALSE FALSE FALSE FALSE
>   DataFrame(ref(evcf)[transition], alt(evcf)[transition])
DataFrame with 2 rows and 2 columns
  ref.evcf..transition. alt.evcf..transition.
         <DNAStringSet>        <DNAStringSet>
1                     G                     A
2                     A                     G
>  
>   ## ---------------------------------------------------------------------
>   ## VRanges objects 
>   ## ---------------------------------------------------------------------
>   ## A VRanges object holds data from a VCF class in a completely
>   ## 'flat' fashion. INFO and FORMAT variables for all subjects are
>   ## 'repped' out such that each row is a unique combination of data.
>   vr <- as(vcf, "VRanges")
Error:   The "ifelse" methods for Rle objects are defunct. Please use

      as(ifelse(test, as.vector(yes), as.vector(no)), "Rle")

  instead.
Execution halted
* checking for unstated dependencies in ‘tests’ ... OK
* checking tests ...
  Running ‘VariantAnnotation_unit_tests.R’ [105s/107s]
 ERROR
Running the tests in ‘tests/VariantAnnotation_unit_tests.R’ failed.
Last 13 lines of output:
       test_VRanges_constructor 
       test_VRanges_vcf 
  
     test_isSNV.R 
       test_isSNV_VRanges 
  
  
  Error in BiocGenerics:::testPackage("VariantAnnotation") : 
    unit tests failed for package VariantAnnotation
  Calls: <Anonymous> -> <Anonymous>
  In addition: Warning message:
  In DataFrame(..., check.names = FALSE) : NAs introduced by coercion
  Execution halted
* checking for unstated dependencies in vignettes ... OK
* checking package vignettes in ‘inst/doc’ ... OK
* checking running R code from vignettes ... SKIPPED
* checking re-building of vignette outputs ... SKIPPED
* checking PDF version of manual ... OK
* DONE

Status: 2 ERRORs, 4 NOTEs
See
  ‘/Users/biocbuild/bbs-3.3-bioc/meat/VariantAnnotation.Rcheck/00check.log’
for details.

VariantAnnotation.Rcheck/tests/VariantAnnotation_unit_tests.Rout.fail:


R Under development (unstable) (2015-10-08 r69496) -- "Unsuffered Consequences"
Copyright (C) 2015 The R Foundation for Statistical Computing
Platform: x86_64-apple-darwin13.4.0 (64-bit)

R is free software and comes with ABSOLUTELY NO WARRANTY.
You are welcome to redistribute it under certain conditions.
Type 'license()' or 'licence()' for distribution details.

R is a collaborative project with many contributors.
Type 'contributors()' for more information and
'citation()' on how to cite R or R packages in publications.

Type 'demo()' for some demos, 'help()' for on-line help, or
'help.start()' for an HTML browser interface to help.
Type 'q()' to quit R.

> require("VariantAnnotation") || stop("unable to load VariantAnnotation package")
Loading required package: VariantAnnotation
Loading required package: BiocGenerics
Loading required package: parallel

Attaching package: 'BiocGenerics'

The following objects are masked from 'package:parallel':

    clusterApply, clusterApplyLB, clusterCall, clusterEvalQ,
    clusterExport, clusterMap, parApply, parCapply, parLapply,
    parLapplyLB, parRapply, parSapply, parSapplyLB

The following objects are masked from 'package:stats':

    IQR, mad, xtabs

The following objects are masked from 'package:base':

    Filter, Find, Map, Position, Reduce, anyDuplicated, append,
    as.data.frame, as.vector, cbind, colnames, do.call, duplicated,
    eval, evalq, get, grep, grepl, intersect, is.unsorted, lapply,
    lengths, mapply, match, mget, order, paste, pmax, pmax.int, pmin,
    pmin.int, rank, rbind, rownames, sapply, setdiff, sort, table,
    tapply, union, unique, unlist, unsplit

Loading required package: GenomeInfoDb
Loading required package: stats4
Loading required package: S4Vectors

Attaching package: 'S4Vectors'

The following object is masked from 'package:base':

    expand.grid

Loading required package: IRanges
Loading required package: GenomicRanges
Loading required package: SummarizedExperiment
Loading required package: Biobase
Welcome to Bioconductor

    Vignettes contain introductory material; view with
    'browseVignettes()'. To cite Bioconductor, see
    'citation("Biobase")', and for packages 'citation("pkgname")'.

Loading required package: Rsamtools
Loading required package: XVector
Loading required package: Biostrings

Attaching package: 'VariantAnnotation'

The following object is masked from 'package:base':

    tabulate

[1] TRUE
> VariantAnnotation:::.test()
Loading required package: RSQLite
Loading required package: DBI
Warning message:
info fields with no header: noMatch 
Timing stopped at: 0.088 0 0.089 
Error :   The "ifelse" methods for Rle objects are defunct. Please use

      as(ifelse(test, as.vector(yes), as.vector(no)), "Rle")

  instead.
Timing stopped at: 1.15 0.007 1.157 
Error :   The "ifelse" methods for Rle objects are defunct. Please use

      as(ifelse(test, as.vector(yes), as.vector(no)), "Rle")

  instead.
Loading required package: survival
Loading required package: Matrix

Attaching package: 'Matrix'

The following object is masked from 'package:VariantAnnotation':

    expand

The following object is masked from 'package:IRanges':

    expand

Timing stopped at: 0.05 0.001 0.05 
Error :   The "ifelse" methods for Rle objects are defunct. Please use

      as(ifelse(test, as.vector(yes), as.vector(no)), "Rle")

  instead.
Loading required package: GenomicFeatures
Loading required package: AnnotationDbi
'select()' returned 1:1 mapping between keys and columns
Loading required package: BSgenome
Loading required package: rtracklayer
'select()' returned many:1 mapping between keys and columns


RUNIT TEST PROTOCOL -- Thu Oct 22 12:24:27 2015 
*********************************************** 
Number of test functions: 89 
Number of errors: 3 
Number of failures: 0 

 
1 Test Suite : 
VariantAnnotation RUnit Tests - 89 test functions, 3 errors, 0 failures
ERROR in test_VRanges_constructor: Error :   The "ifelse" methods for Rle objects are defunct. Please use

      as(ifelse(test, as.vector(yes), as.vector(no)), "Rle")

  instead.
ERROR in test_VRanges_vcf: Error :   The "ifelse" methods for Rle objects are defunct. Please use

      as(ifelse(test, as.vector(yes), as.vector(no)), "Rle")

  instead.
ERROR in test_isSNV_VRanges: Error :   The "ifelse" methods for Rle objects are defunct. Please use

      as(ifelse(test, as.vector(yes), as.vector(no)), "Rle")

  instead.

Test files with failing tests

   test_VRanges-class.R 
     test_VRanges_constructor 
     test_VRanges_vcf 

   test_isSNV.R 
     test_isSNV_VRanges 


Error in BiocGenerics:::testPackage("VariantAnnotation") : 
  unit tests failed for package VariantAnnotation
Calls: <Anonymous> -> <Anonymous>
In addition: Warning message:
In DataFrame(..., check.names = FALSE) : NAs introduced by coercion
Execution halted

VariantAnnotation.Rcheck/00install.out:

* installing *source* package ‘VariantAnnotation’ ...
** libs
clang -I/Library/Frameworks/R.framework/Resources/include -DNDEBUG -D_USE_KNETFILE -DBGZF_CACHE -D_FILE_OFFSET_BITS=64 -D_LARGEFILE64_SOURCE -I/usr/local/include -I/usr/local/include/freetype2 -I/opt/X11/include -I"/Library/Frameworks/R.framework/Versions/3.3/Resources/library/S4Vectors/include" -I"/Library/Frameworks/R.framework/Versions/3.3/Resources/library/IRanges/include" -I"/Library/Frameworks/R.framework/Versions/3.3/Resources/library/XVector/include" -I"/Library/Frameworks/R.framework/Versions/3.3/Resources/library/Biostrings/include" -I"/Library/Frameworks/R.framework/Versions/3.3/Resources/library/Rsamtools/include"   -fPIC  -Wall -mtune=core2 -g -O2  -c Biostrings_stubs.c -o Biostrings_stubs.o
clang -I/Library/Frameworks/R.framework/Resources/include -DNDEBUG -D_USE_KNETFILE -DBGZF_CACHE -D_FILE_OFFSET_BITS=64 -D_LARGEFILE64_SOURCE -I/usr/local/include -I/usr/local/include/freetype2 -I/opt/X11/include -I"/Library/Frameworks/R.framework/Versions/3.3/Resources/library/S4Vectors/include" -I"/Library/Frameworks/R.framework/Versions/3.3/Resources/library/IRanges/include" -I"/Library/Frameworks/R.framework/Versions/3.3/Resources/library/XVector/include" -I"/Library/Frameworks/R.framework/Versions/3.3/Resources/library/Biostrings/include" -I"/Library/Frameworks/R.framework/Versions/3.3/Resources/library/Rsamtools/include"   -fPIC  -Wall -mtune=core2 -g -O2  -c IRanges_stubs.c -o IRanges_stubs.o
clang -I/Library/Frameworks/R.framework/Resources/include -DNDEBUG -D_USE_KNETFILE -DBGZF_CACHE -D_FILE_OFFSET_BITS=64 -D_LARGEFILE64_SOURCE -I/usr/local/include -I/usr/local/include/freetype2 -I/opt/X11/include -I"/Library/Frameworks/R.framework/Versions/3.3/Resources/library/S4Vectors/include" -I"/Library/Frameworks/R.framework/Versions/3.3/Resources/library/IRanges/include" -I"/Library/Frameworks/R.framework/Versions/3.3/Resources/library/XVector/include" -I"/Library/Frameworks/R.framework/Versions/3.3/Resources/library/Biostrings/include" -I"/Library/Frameworks/R.framework/Versions/3.3/Resources/library/Rsamtools/include"   -fPIC  -Wall -mtune=core2 -g -O2  -c R_init_VariantAnnotation.c -o R_init_VariantAnnotation.o
clang -I/Library/Frameworks/R.framework/Resources/include -DNDEBUG -D_USE_KNETFILE -DBGZF_CACHE -D_FILE_OFFSET_BITS=64 -D_LARGEFILE64_SOURCE -I/usr/local/include -I/usr/local/include/freetype2 -I/opt/X11/include -I"/Library/Frameworks/R.framework/Versions/3.3/Resources/library/S4Vectors/include" -I"/Library/Frameworks/R.framework/Versions/3.3/Resources/library/IRanges/include" -I"/Library/Frameworks/R.framework/Versions/3.3/Resources/library/XVector/include" -I"/Library/Frameworks/R.framework/Versions/3.3/Resources/library/Biostrings/include" -I"/Library/Frameworks/R.framework/Versions/3.3/Resources/library/Rsamtools/include"   -fPIC  -Wall -mtune=core2 -g -O2  -c XVector_stubs.c -o XVector_stubs.o
clang -I/Library/Frameworks/R.framework/Resources/include -DNDEBUG -D_USE_KNETFILE -DBGZF_CACHE -D_FILE_OFFSET_BITS=64 -D_LARGEFILE64_SOURCE -I/usr/local/include -I/usr/local/include/freetype2 -I/opt/X11/include -I"/Library/Frameworks/R.framework/Versions/3.3/Resources/library/S4Vectors/include" -I"/Library/Frameworks/R.framework/Versions/3.3/Resources/library/IRanges/include" -I"/Library/Frameworks/R.framework/Versions/3.3/Resources/library/XVector/include" -I"/Library/Frameworks/R.framework/Versions/3.3/Resources/library/Biostrings/include" -I"/Library/Frameworks/R.framework/Versions/3.3/Resources/library/Rsamtools/include"   -fPIC  -Wall -mtune=core2 -g -O2  -c dna_hash.c -o dna_hash.o
dna_hash.c:10:1: warning: unused function 'kh_clear_ref' [-Wunused-function]
KHASH_MAP_INIT_STR(ref, int)
^
/Library/Frameworks/R.framework/Versions/3.3/Resources/library/Rsamtools/include/samtools/khash.h:526:2: note: expanded from macro 'KHASH_MAP_INIT_STR'
        KHASH_INIT(name, kh_cstr_t, khval_t, 1, kh_str_hash_func, kh_str_hash_equal)
        ^
/Library/Frameworks/R.framework/Versions/3.3/Resources/library/Rsamtools/include/samtools/khash.h:307:2: note: expanded from macro 'KHASH_INIT'
        KHASH_INIT2(name, static inline, khkey_t, khval_t, kh_is_map, __hash_func, __hash_equal)
        ^
/Library/Frameworks/R.framework/Versions/3.3/Resources/library/Rsamtools/include/samtools/khash.h:179:13: note: expanded from macro 'KHASH_INIT2'
        SCOPE void kh_clear_##name(kh_##name##_t *h)                                            \
                   ^
<scratch space>:213:1: note: expanded from here
kh_clear_ref
^
dna_hash.c:10:1: warning: unused function 'kh_del_ref' [-Wunused-function]
/Library/Frameworks/R.framework/Versions/3.3/Resources/library/Rsamtools/include/samtools/khash.h:526:2: note: expanded from macro 'KHASH_MAP_INIT_STR'
        KHASH_INIT(name, kh_cstr_t, khval_t, 1, kh_str_hash_func, kh_str_hash_equal)
        ^
/Library/Frameworks/R.framework/Versions/3.3/Resources/library/Rsamtools/include/samtools/khash.h:307:2: note: expanded from macro 'KHASH_INIT'
        KHASH_INIT2(name, static inline, khkey_t, khval_t, kh_is_map, __hash_func, __hash_equal)
        ^
/Library/Frameworks/R.framework/Versions/3.3/Resources/library/Rsamtools/include/samtools/khash.h:298:13: note: expanded from macro 'KHASH_INIT2'
        SCOPE void kh_del_##name(kh_##name##_t *h, khint_t x)                           \
                   ^
<scratch space>:13:1: note: expanded from here
kh_del_ref
^
2 warnings generated.
clang -I/Library/Frameworks/R.framework/Resources/include -DNDEBUG -D_USE_KNETFILE -DBGZF_CACHE -D_FILE_OFFSET_BITS=64 -D_LARGEFILE64_SOURCE -I/usr/local/include -I/usr/local/include/freetype2 -I/opt/X11/include -I"/Library/Frameworks/R.framework/Versions/3.3/Resources/library/S4Vectors/include" -I"/Library/Frameworks/R.framework/Versions/3.3/Resources/library/IRanges/include" -I"/Library/Frameworks/R.framework/Versions/3.3/Resources/library/XVector/include" -I"/Library/Frameworks/R.framework/Versions/3.3/Resources/library/Biostrings/include" -I"/Library/Frameworks/R.framework/Versions/3.3/Resources/library/Rsamtools/include"   -fPIC  -Wall -mtune=core2 -g -O2  -c rle.c -o rle.o
clang -I/Library/Frameworks/R.framework/Resources/include -DNDEBUG -D_USE_KNETFILE -DBGZF_CACHE -D_FILE_OFFSET_BITS=64 -D_LARGEFILE64_SOURCE -I/usr/local/include -I/usr/local/include/freetype2 -I/opt/X11/include -I"/Library/Frameworks/R.framework/Versions/3.3/Resources/library/S4Vectors/include" -I"/Library/Frameworks/R.framework/Versions/3.3/Resources/library/IRanges/include" -I"/Library/Frameworks/R.framework/Versions/3.3/Resources/library/XVector/include" -I"/Library/Frameworks/R.framework/Versions/3.3/Resources/library/Biostrings/include" -I"/Library/Frameworks/R.framework/Versions/3.3/Resources/library/Rsamtools/include"   -fPIC  -Wall -mtune=core2 -g -O2  -c strhash.c -o strhash.o
clang -I/Library/Frameworks/R.framework/Resources/include -DNDEBUG -D_USE_KNETFILE -DBGZF_CACHE -D_FILE_OFFSET_BITS=64 -D_LARGEFILE64_SOURCE -I/usr/local/include -I/usr/local/include/freetype2 -I/opt/X11/include -I"/Library/Frameworks/R.framework/Versions/3.3/Resources/library/S4Vectors/include" -I"/Library/Frameworks/R.framework/Versions/3.3/Resources/library/IRanges/include" -I"/Library/Frameworks/R.framework/Versions/3.3/Resources/library/XVector/include" -I"/Library/Frameworks/R.framework/Versions/3.3/Resources/library/Biostrings/include" -I"/Library/Frameworks/R.framework/Versions/3.3/Resources/library/Rsamtools/include"   -fPIC  -Wall -mtune=core2 -g -O2  -c utilities.c -o utilities.o
clang -I/Library/Frameworks/R.framework/Resources/include -DNDEBUG -D_USE_KNETFILE -DBGZF_CACHE -D_FILE_OFFSET_BITS=64 -D_LARGEFILE64_SOURCE -I/usr/local/include -I/usr/local/include/freetype2 -I/opt/X11/include -I"/Library/Frameworks/R.framework/Versions/3.3/Resources/library/S4Vectors/include" -I"/Library/Frameworks/R.framework/Versions/3.3/Resources/library/IRanges/include" -I"/Library/Frameworks/R.framework/Versions/3.3/Resources/library/XVector/include" -I"/Library/Frameworks/R.framework/Versions/3.3/Resources/library/Biostrings/include" -I"/Library/Frameworks/R.framework/Versions/3.3/Resources/library/Rsamtools/include"   -fPIC  -Wall -mtune=core2 -g -O2  -c vcffile.c -o vcffile.o
vcffile.c:20:1: warning: unused function 'kh_clear_WARNINGS' [-Wunused-function]
KHASH_SET_INIT_STR(WARNINGS)
^
/Library/Frameworks/R.framework/Versions/3.3/Resources/library/Rsamtools/include/samtools/khash.h:518:2: note: expanded from macro 'KHASH_SET_INIT_STR'
        KHASH_INIT(name, kh_cstr_t, char, 0, kh_str_hash_func, kh_str_hash_equal)
        ^
/Library/Frameworks/R.framework/Versions/3.3/Resources/library/Rsamtools/include/samtools/khash.h:307:2: note: expanded from macro 'KHASH_INIT'
        KHASH_INIT2(name, static inline, khkey_t, khval_t, kh_is_map, __hash_func, __hash_equal)
        ^
/Library/Frameworks/R.framework/Versions/3.3/Resources/library/Rsamtools/include/samtools/khash.h:179:13: note: expanded from macro 'KHASH_INIT2'
        SCOPE void kh_clear_##name(kh_##name##_t *h)                                            \
                   ^
<scratch space>:89:1: note: expanded from here
kh_clear_WARNINGS
^
vcffile.c:20:1: warning: unused function 'kh_del_WARNINGS' [-Wunused-function]
/Library/Frameworks/R.framework/Versions/3.3/Resources/library/Rsamtools/include/samtools/khash.h:518:2: note: expanded from macro 'KHASH_SET_INIT_STR'
        KHASH_INIT(name, kh_cstr_t, char, 0, kh_str_hash_func, kh_str_hash_equal)
        ^
/Library/Frameworks/R.framework/Versions/3.3/Resources/library/Rsamtools/include/samtools/khash.h:307:2: note: expanded from macro 'KHASH_INIT'
        KHASH_INIT2(name, static inline, khkey_t, khval_t, kh_is_map, __hash_func, __hash_equal)
        ^
/Library/Frameworks/R.framework/Versions/3.3/Resources/library/Rsamtools/include/samtools/khash.h:298:13: note: expanded from macro 'KHASH_INIT2'
        SCOPE void kh_del_##name(kh_##name##_t *h, khint_t x)                           \
                   ^
<scratch space>:103:1: note: expanded from here
kh_del_WARNINGS
^
2 warnings generated.
clang -I/Library/Frameworks/R.framework/Resources/include -DNDEBUG -D_USE_KNETFILE -DBGZF_CACHE -D_FILE_OFFSET_BITS=64 -D_LARGEFILE64_SOURCE -I/usr/local/include -I/usr/local/include/freetype2 -I/opt/X11/include -I"/Library/Frameworks/R.framework/Versions/3.3/Resources/library/S4Vectors/include" -I"/Library/Frameworks/R.framework/Versions/3.3/Resources/library/IRanges/include" -I"/Library/Frameworks/R.framework/Versions/3.3/Resources/library/XVector/include" -I"/Library/Frameworks/R.framework/Versions/3.3/Resources/library/Biostrings/include" -I"/Library/Frameworks/R.framework/Versions/3.3/Resources/library/Rsamtools/include"   -fPIC  -Wall -mtune=core2 -g -O2  -c vcftype.c -o vcftype.o
clang -I/Library/Frameworks/R.framework/Resources/include -DNDEBUG -D_USE_KNETFILE -DBGZF_CACHE -D_FILE_OFFSET_BITS=64 -D_LARGEFILE64_SOURCE -I/usr/local/include -I/usr/local/include/freetype2 -I/opt/X11/include -I"/Library/Frameworks/R.framework/Versions/3.3/Resources/library/S4Vectors/include" -I"/Library/Frameworks/R.framework/Versions/3.3/Resources/library/IRanges/include" -I"/Library/Frameworks/R.framework/Versions/3.3/Resources/library/XVector/include" -I"/Library/Frameworks/R.framework/Versions/3.3/Resources/library/Biostrings/include" -I"/Library/Frameworks/R.framework/Versions/3.3/Resources/library/Rsamtools/include"   -fPIC  -Wall -mtune=core2 -g -O2  -c writevcf.c -o writevcf.o
clang -dynamiclib -Wl,-headerpad_max_install_names -undefined dynamic_lookup -single_module -multiply_defined suppress -L/Library/Frameworks/R.framework/Resources/lib -L/usr/local/lib -o VariantAnnotation.so Biostrings_stubs.o IRanges_stubs.o R_init_VariantAnnotation.o XVector_stubs.o dna_hash.o rle.o strhash.o utilities.o vcffile.o vcftype.o writevcf.o /Library/Frameworks/R.framework/Versions/3.3/Resources/library/Rsamtools/usrlib//libbam.a /Library/Frameworks/R.framework/Versions/3.3/Resources/library/Rsamtools/usrlib//libbcf.a /Library/Frameworks/R.framework/Versions/3.3/Resources/library/Rsamtools/usrlib//libtabix.a -lz -pthread -F/Library/Frameworks/R.framework/.. -framework R -Wl,-framework -Wl,CoreFoundation
clang: warning: argument unused during compilation: '-pthread'
installing to /Users/biocbuild/bbs-3.3-bioc/meat/VariantAnnotation.Rcheck/VariantAnnotation/libs
** R
** inst
** preparing package for lazy loading
Creating a new generic function for ‘tabulate’ in package ‘VariantAnnotation’
** help
*** installing help indices
** building package indices
** installing vignettes
** testing if installed package can be loaded
* DONE (VariantAnnotation)

VariantAnnotation.Rcheck/VariantAnnotation-Ex.timings:

nameusersystemelapsed
GLtoGP0.5790.1380.756
PROVEANDb-class 4.692 1.47321.675
PolyPhenDb-class 1.027 0.30034.548
SIFTDb-class0.0020.0000.002
ScanVcfParam-class0.5300.0470.625
VCF-class0.8180.0150.833
VCFHeader-class0.0360.0010.036
VRanges-class0.2140.0000.216
VRangesList-class0.2050.0020.221
VariantType-class0.0060.0010.006
VcfFile-class0.2360.0210.286
filterVcf-methods1.2730.0791.369
genotypeToSnpMatrix-methods1.7970.1202.029
getTranscriptSeqs-methods0.0010.0000.000