Maaslin2.Rcheck/tests_i386/testthat.Rout
R version 4.0.5 (2021-03-31) -- "Shake and Throw"
Copyright (C) 2021 The R Foundation for Statistical Computing
Platform: i386-w64-mingw32/i386 (32-bit)
R is free software and comes with ABSOLUTELY NO WARRANTY.
You are welcome to redistribute it under certain conditions.
Type 'license()' or 'licence()' for distribution details.
R is a collaborative project with many contributors.
Type 'contributors()' for more information and
'citation()' on how to cite R or R packages in publications.
Type 'demo()' for some demos, 'help()' for on-line help, or
'help.start()' for an HTML browser interface to help.
Type 'q()' to quit R.
> library(testthat)
> library(Maaslin2)
>
> test_check("Maaslin2")
[1] "Creating output folder"
2021-05-06 04:15:46 INFO::Writing function arguments to log file
2021-05-06 04:15:46 INFO::Verifying options selected are valid
2021-05-06 04:15:46 INFO::Determining format of input files
2021-05-06 04:15:46 INFO::Input format is data samples as rows and metadata samples as rows
2021-05-06 04:15:46 INFO::Formula for random effects: expr ~ (1 | site) + (1 | subject)
2021-05-06 04:15:46 INFO::Formula for fixed effects: expr ~ diagnosis + dysbiosisnonIBD + dysbiosisUC + dysbiosisCD + antibiotics + age
2021-05-06 04:15:46 INFO::Filter data based on min abundance and min prevalence
2021-05-06 04:15:46 INFO::Total samples in data: 1595
2021-05-06 04:15:46 INFO::Min samples required with min abundance for a feature not to be filtered: 159.500000
2021-05-06 04:15:46 INFO::Total filtered features: 0
2021-05-06 04:15:46 INFO::Filtered feature names from abundance and prevalence filtering:
2021-05-06 04:15:46 INFO::Running selected normalization method: TSS
2021-05-06 04:15:47 INFO::Total filtered features with variance filtering: 0
2021-05-06 04:15:47 INFO::Filtered feature names from variance filtering:
2021-05-06 04:15:47 INFO::Bypass z-score application to metadata
2021-05-06 04:15:47 INFO::Running selected transform method: AST
2021-05-06 04:15:47 INFO::Running selected analysis method: LM
2021-05-06 04:15:47 INFO::Fitting model to feature number 1, Bifidobacterium.adolescentis
2021-05-06 04:15:49 INFO::Fitting model to feature number 2, Bifidobacterium.bifidum
2021-05-06 04:15:49 INFO::Fitting model to feature number 3, Bifidobacterium.longum
2021-05-06 04:15:49 INFO::Fitting model to feature number 4, Bifidobacterium.pseudocatenulatum
2021-05-06 04:15:49 INFO::Fitting model to feature number 5, Collinsella.aerofaciens
2021-05-06 04:15:50 INFO::Fitting model to feature number 6, Bacteroides.caccae
2021-05-06 04:15:50 INFO::Fitting model to feature number 7, Bacteroides.cellulosilyticus
2021-05-06 04:15:50 INFO::Fitting model to feature number 8, Bacteroides.dorei
2021-05-06 04:15:50 INFO::Fitting model to feature number 9, Bacteroides.eggerthii
2021-05-06 04:15:50 INFO::Fitting model to feature number 10, Bacteroides.faecis
2021-05-06 04:15:50 INFO::Fitting model to feature number 11, Bacteroides.finegoldii
2021-05-06 04:15:51 INFO::Fitting model to feature number 12, Bacteroides.fragilis
2021-05-06 04:15:51 INFO::Fitting model to feature number 13, Bacteroides.intestinalis
2021-05-06 04:15:51 INFO::Fitting model to feature number 14, Bacteroides.massiliensis
2021-05-06 04:15:51 INFO::Fitting model to feature number 15, Bacteroides.ovatus
2021-05-06 04:15:51 INFO::Fitting model to feature number 16, Bacteroides.salyersiae
2021-05-06 04:15:52 INFO::Fitting model to feature number 17, Bacteroides.stercoris
2021-05-06 04:15:52 INFO::Fitting model to feature number 18, Bacteroides.thetaiotaomicron
2021-05-06 04:15:52 INFO::Fitting model to feature number 19, Bacteroides.uniformis
2021-05-06 04:15:52 INFO::Fitting model to feature number 20, Bacteroides.vulgatus
2021-05-06 04:15:52 INFO::Fitting model to feature number 21, Bacteroides.xylanisolvens
2021-05-06 04:15:53 INFO::Fitting model to feature number 22, Bacteroidales.bacterium.ph8
2021-05-06 04:15:53 INFO::Fitting model to feature number 23, Barnesiella.intestinihominis
2021-05-06 04:15:53 INFO::Fitting model to feature number 24, Coprobacter.fastidiosus
2021-05-06 04:15:53 INFO::Fitting model to feature number 25, Odoribacter.splanchnicus
2021-05-06 04:15:53 INFO::Fitting model to feature number 26, Parabacteroides.distasonis
2021-05-06 04:15:53 INFO::Fitting model to feature number 27, Parabacteroides.goldsteinii
2021-05-06 04:15:54 INFO::Fitting model to feature number 28, Parabacteroides.merdae
2021-05-06 04:15:54 INFO::Fitting model to feature number 29, Parabacteroides.unclassified
2021-05-06 04:15:54 INFO::Fitting model to feature number 30, Paraprevotella.clara
2021-05-06 04:15:54 INFO::Fitting model to feature number 31, Paraprevotella.unclassified
2021-05-06 04:15:54 INFO::Fitting model to feature number 32, Prevotella.copri
2021-05-06 04:15:54 INFO::Fitting model to feature number 33, Alistipes.finegoldii
2021-05-06 04:15:55 INFO::Fitting model to feature number 34, Alistipes.onderdonkii
2021-05-06 04:15:55 INFO::Fitting model to feature number 35, Alistipes.putredinis
2021-05-06 04:15:55 INFO::Fitting model to feature number 36, Alistipes.shahii
2021-05-06 04:15:55 INFO::Fitting model to feature number 37, Alistipes.unclassified
2021-05-06 04:15:55 INFO::Fitting model to feature number 38, Streptococcus.salivarius
2021-05-06 04:15:55 INFO::Fitting model to feature number 39, Clostridium.bolteae
2021-05-06 04:15:56 INFO::Fitting model to feature number 40, Clostridium.citroniae
2021-05-06 04:15:56 INFO::Fitting model to feature number 41, Clostridium.clostridioforme
2021-05-06 04:15:56 INFO::Fitting model to feature number 42, Clostridium.hathewayi
2021-05-06 04:15:56 INFO::Fitting model to feature number 43, Clostridium.leptum
2021-05-06 04:15:56 INFO::Fitting model to feature number 44, Clostridium.nexile
2021-05-06 04:15:56 INFO::Fitting model to feature number 45, Clostridium.symbiosum
2021-05-06 04:15:57 INFO::Fitting model to feature number 46, Flavonifractor.plautii
2021-05-06 04:15:57 INFO::Fitting model to feature number 47, Eubacterium.eligens
2021-05-06 04:15:57 INFO::Fitting model to feature number 48, Eubacterium.hallii
2021-05-06 04:15:57 INFO::Fitting model to feature number 49, Eubacterium.rectale
2021-05-06 04:15:58 INFO::Fitting model to feature number 50, Eubacterium.siraeum
2021-05-06 04:15:58 INFO::Fitting model to feature number 51, Eubacterium.sp.3.1.31
2021-05-06 04:15:58 INFO::Fitting model to feature number 52, Eubacterium.ventriosum
2021-05-06 04:15:58 INFO::Fitting model to feature number 53, Ruminococcus.gnavus
2021-05-06 04:15:59 INFO::Fitting model to feature number 54, Ruminococcus.obeum
2021-05-06 04:15:59 INFO::Fitting model to feature number 55, Ruminococcus.torques
2021-05-06 04:15:59 INFO::Fitting model to feature number 56, Coprococcus.comes
2021-05-06 04:16:00 INFO::Fitting model to feature number 57, Dorea.longicatena
2021-05-06 04:16:00 INFO::Fitting model to feature number 58, Lachnospiraceae.bacterium.1.1.57FAA
2021-05-06 04:16:00 INFO::Fitting model to feature number 59, Lachnospiraceae.bacterium.3.1.46FAA
2021-05-06 04:16:00 INFO::Fitting model to feature number 60, Roseburia.hominis
2021-05-06 04:16:01 INFO::Fitting model to feature number 61, Roseburia.intestinalis
2021-05-06 04:16:01 INFO::Fitting model to feature number 62, Roseburia.inulinivorans
2021-05-06 04:16:01 INFO::Fitting model to feature number 63, Roseburia.unclassified
2021-05-06 04:16:02 INFO::Fitting model to feature number 64, Oscillibacter.unclassified
2021-05-06 04:16:02 INFO::Fitting model to feature number 65, Peptostreptococcaceae.noname.unclassified
2021-05-06 04:16:02 INFO::Fitting model to feature number 66, Faecalibacterium.prausnitzii
2021-05-06 04:16:02 INFO::Fitting model to feature number 67, Ruminococcus.bromii
2021-05-06 04:16:03 INFO::Fitting model to feature number 68, Ruminococcus.callidus
2021-05-06 04:16:03 INFO::Fitting model to feature number 69, Ruminococcus.lactaris
2021-05-06 04:16:03 INFO::Fitting model to feature number 70, Subdoligranulum.unclassified
2021-05-06 04:16:04 INFO::Fitting model to feature number 71, Coprobacillus.unclassified
2021-05-06 04:16:04 INFO::Fitting model to feature number 72, Acidaminococcus.unclassified
2021-05-06 04:16:04 INFO::Fitting model to feature number 73, Dialister.invisus
2021-05-06 04:16:04 INFO::Fitting model to feature number 74, Veillonella.atypica
2021-05-06 04:16:05 INFO::Fitting model to feature number 75, Veillonella.dispar
2021-05-06 04:16:05 INFO::Fitting model to feature number 76, Veillonella.parvula
2021-05-06 04:16:05 INFO::Fitting model to feature number 77, Veillonella.unclassified
2021-05-06 04:16:05 INFO::Fitting model to feature number 78, Burkholderiales.bacterium.1.1.47
2021-05-06 04:16:06 INFO::Fitting model to feature number 79, Parasutterella.excrementihominis
2021-05-06 04:16:06 INFO::Fitting model to feature number 80, Sutterella.wadsworthensis
2021-05-06 04:16:06 INFO::Fitting model to feature number 81, Bilophila.unclassified
2021-05-06 04:16:06 INFO::Fitting model to feature number 82, Escherichia.coli
2021-05-06 04:16:06 INFO::Fitting model to feature number 83, Escherichia.unclassified
2021-05-06 04:16:07 INFO::Fitting model to feature number 84, Klebsiella.pneumoniae
2021-05-06 04:16:07 INFO::Fitting model to feature number 85, Haemophilus.parainfluenzae
2021-05-06 04:16:07 INFO::Fitting model to feature number 86, Akkermansia.muciniphila
2021-05-06 04:16:07 INFO::Fitting model to feature number 87, C2likevirus.unclassified
2021-05-06 04:16:08 INFO::Counting total values for each feature
2021-05-06 04:16:08 INFO::Writing residuals to file output/residuals.rds
2021-05-06 04:16:08 INFO::Writing all results to file (ordered by increasing q-values): output/all_results.tsv
2021-05-06 04:16:08 INFO::Writing the significant results (those which are less than or equal to the threshold of 0.250000 ) to file (ordered by increasing q-values): output/significant_results.tsv
[1] "Creating output folder"
2021-05-06 04:16:08 INFO::Writing function arguments to log file
2021-05-06 04:16:08 INFO::Verifying options selected are valid
2021-05-06 04:16:08 INFO::Determining format of input files
2021-05-06 04:16:08 INFO::Input format is data samples as rows and metadata samples as rows
2021-05-06 04:16:08 INFO::Formula for random effects: expr ~ (1 | site) + (1 | subject)
2021-05-06 04:16:08 INFO::Formula for fixed effects: expr ~ diagnosis + dysbiosis + antibiotics + age
2021-05-06 04:16:08 INFO::Filter data based on min abundance and min prevalence
2021-05-06 04:16:08 INFO::Total samples in data: 1595
2021-05-06 04:16:08 INFO::Min samples required with min abundance for a feature not to be filtered: 159.500000
2021-05-06 04:16:08 INFO::Total filtered features: 0
2021-05-06 04:16:08 INFO::Filtered feature names from abundance and prevalence filtering:
2021-05-06 04:16:08 INFO::Running selected normalization method: NONE
2021-05-06 04:16:08 INFO::Total filtered features with variance filtering: 0
2021-05-06 04:16:08 INFO::Filtered feature names from variance filtering:
2021-05-06 04:16:08 INFO::Bypass z-score application to metadata
2021-05-06 04:16:08 INFO::Running selected transform method: AST
2021-05-06 04:16:08 INFO::Running selected analysis method: LM
2021-05-06 04:16:08 INFO::Fitting model to feature number 1, Bifidobacterium.adolescentis
2021-05-06 04:16:08 INFO::Fitting model to feature number 2, Bifidobacterium.bifidum
2021-05-06 04:16:08 INFO::Fitting model to feature number 3, Bifidobacterium.longum
2021-05-06 04:16:08 INFO::Fitting model to feature number 4, Bifidobacterium.pseudocatenulatum
2021-05-06 04:16:09 INFO::Fitting model to feature number 5, Collinsella.aerofaciens
2021-05-06 04:16:09 INFO::Fitting model to feature number 6, Bacteroides.caccae
2021-05-06 04:16:09 INFO::Fitting model to feature number 7, Bacteroides.cellulosilyticus
2021-05-06 04:16:09 INFO::Fitting model to feature number 8, Bacteroides.dorei
2021-05-06 04:16:09 INFO::Fitting model to feature number 9, Bacteroides.eggerthii
2021-05-06 04:16:09 INFO::Fitting model to feature number 10, Bacteroides.faecis
2021-05-06 04:16:10 INFO::Fitting model to feature number 11, Bacteroides.finegoldii
2021-05-06 04:16:10 INFO::Fitting model to feature number 12, Bacteroides.fragilis
2021-05-06 04:16:10 INFO::Fitting model to feature number 13, Bacteroides.intestinalis
2021-05-06 04:16:10 INFO::Fitting model to feature number 14, Bacteroides.massiliensis
2021-05-06 04:16:10 INFO::Fitting model to feature number 15, Bacteroides.ovatus
2021-05-06 04:16:11 INFO::Fitting model to feature number 16, Bacteroides.salyersiae
2021-05-06 04:16:11 INFO::Fitting model to feature number 17, Bacteroides.stercoris
2021-05-06 04:16:11 INFO::Fitting model to feature number 18, Bacteroides.thetaiotaomicron
2021-05-06 04:16:11 INFO::Fitting model to feature number 19, Bacteroides.uniformis
2021-05-06 04:16:12 INFO::Fitting model to feature number 20, Bacteroides.vulgatus
2021-05-06 04:16:12 INFO::Fitting model to feature number 21, Bacteroides.xylanisolvens
2021-05-06 04:16:12 INFO::Fitting model to feature number 22, Bacteroidales.bacterium.ph8
2021-05-06 04:16:12 INFO::Fitting model to feature number 23, Barnesiella.intestinihominis
2021-05-06 04:16:13 INFO::Fitting model to feature number 24, Coprobacter.fastidiosus
2021-05-06 04:16:13 INFO::Fitting model to feature number 25, Odoribacter.splanchnicus
2021-05-06 04:16:13 INFO::Fitting model to feature number 26, Parabacteroides.distasonis
2021-05-06 04:16:13 INFO::Fitting model to feature number 27, Parabacteroides.goldsteinii
2021-05-06 04:16:13 INFO::Fitting model to feature number 28, Parabacteroides.merdae
2021-05-06 04:16:14 INFO::Fitting model to feature number 29, Parabacteroides.unclassified
2021-05-06 04:16:14 INFO::Fitting model to feature number 30, Paraprevotella.clara
2021-05-06 04:16:14 INFO::Fitting model to feature number 31, Paraprevotella.unclassified
2021-05-06 04:16:14 INFO::Fitting model to feature number 32, Prevotella.copri
2021-05-06 04:16:15 INFO::Fitting model to feature number 33, Alistipes.finegoldii
2021-05-06 04:16:15 INFO::Fitting model to feature number 34, Alistipes.onderdonkii
2021-05-06 04:16:15 INFO::Fitting model to feature number 35, Alistipes.putredinis
2021-05-06 04:16:15 INFO::Fitting model to feature number 36, Alistipes.shahii
2021-05-06 04:16:16 INFO::Fitting model to feature number 37, Alistipes.unclassified
2021-05-06 04:16:16 INFO::Fitting model to feature number 38, Streptococcus.salivarius
2021-05-06 04:16:16 INFO::Fitting model to feature number 39, Clostridium.bolteae
2021-05-06 04:16:16 INFO::Fitting model to feature number 40, Clostridium.citroniae
2021-05-06 04:16:17 INFO::Fitting model to feature number 41, Clostridium.clostridioforme
2021-05-06 04:16:17 INFO::Fitting model to feature number 42, Clostridium.hathewayi
2021-05-06 04:16:17 INFO::Fitting model to feature number 43, Clostridium.leptum
2021-05-06 04:16:17 INFO::Fitting model to feature number 44, Clostridium.nexile
2021-05-06 04:16:18 INFO::Fitting model to feature number 45, Clostridium.symbiosum
2021-05-06 04:16:18 INFO::Fitting model to feature number 46, Flavonifractor.plautii
2021-05-06 04:16:18 INFO::Fitting model to feature number 47, Eubacterium.eligens
2021-05-06 04:16:18 INFO::Fitting model to feature number 48, Eubacterium.hallii
2021-05-06 04:16:18 INFO::Fitting model to feature number 49, Eubacterium.rectale
2021-05-06 04:16:18 INFO::Fitting model to feature number 50, Eubacterium.siraeum
2021-05-06 04:16:19 INFO::Fitting model to feature number 51, Eubacterium.sp.3.1.31
2021-05-06 04:16:19 INFO::Fitting model to feature number 52, Eubacterium.ventriosum
2021-05-06 04:16:19 INFO::Fitting model to feature number 53, Ruminococcus.gnavus
2021-05-06 04:16:19 INFO::Fitting model to feature number 54, Ruminococcus.obeum
2021-05-06 04:16:19 INFO::Fitting model to feature number 55, Ruminococcus.torques
2021-05-06 04:16:20 INFO::Fitting model to feature number 56, Coprococcus.comes
2021-05-06 04:16:20 INFO::Fitting model to feature number 57, Dorea.longicatena
2021-05-06 04:16:20 INFO::Fitting model to feature number 58, Lachnospiraceae.bacterium.1.1.57FAA
2021-05-06 04:16:20 INFO::Fitting model to feature number 59, Lachnospiraceae.bacterium.3.1.46FAA
2021-05-06 04:16:20 INFO::Fitting model to feature number 60, Roseburia.hominis
2021-05-06 04:16:20 INFO::Fitting model to feature number 61, Roseburia.intestinalis
2021-05-06 04:16:21 INFO::Fitting model to feature number 62, Roseburia.inulinivorans
2021-05-06 04:16:21 INFO::Fitting model to feature number 63, Roseburia.unclassified
2021-05-06 04:16:21 INFO::Fitting model to feature number 64, Oscillibacter.unclassified
2021-05-06 04:16:21 INFO::Fitting model to feature number 65, Peptostreptococcaceae.noname.unclassified
2021-05-06 04:16:21 INFO::Fitting model to feature number 66, Faecalibacterium.prausnitzii
2021-05-06 04:16:21 INFO::Fitting model to feature number 67, Ruminococcus.bromii
2021-05-06 04:16:22 INFO::Fitting model to feature number 68, Ruminococcus.callidus
2021-05-06 04:16:22 INFO::Fitting model to feature number 69, Ruminococcus.lactaris
2021-05-06 04:16:22 INFO::Fitting model to feature number 70, Subdoligranulum.unclassified
2021-05-06 04:16:22 INFO::Fitting model to feature number 71, Coprobacillus.unclassified
2021-05-06 04:16:23 INFO::Fitting model to feature number 72, Acidaminococcus.unclassified
2021-05-06 04:16:23 INFO::Fitting model to feature number 73, Dialister.invisus
2021-05-06 04:16:23 INFO::Fitting model to feature number 74, Veillonella.atypica
2021-05-06 04:16:24 INFO::Fitting model to feature number 75, Veillonella.dispar
2021-05-06 04:16:24 INFO::Fitting model to feature number 76, Veillonella.parvula
2021-05-06 04:16:24 INFO::Fitting model to feature number 77, Veillonella.unclassified
2021-05-06 04:16:24 INFO::Fitting model to feature number 78, Burkholderiales.bacterium.1.1.47
2021-05-06 04:16:24 INFO::Fitting model to feature number 79, Parasutterella.excrementihominis
2021-05-06 04:16:25 INFO::Fitting model to feature number 80, Sutterella.wadsworthensis
2021-05-06 04:16:25 INFO::Fitting model to feature number 81, Bilophila.unclassified
2021-05-06 04:16:25 INFO::Fitting model to feature number 82, Escherichia.coli
2021-05-06 04:16:25 INFO::Fitting model to feature number 83, Escherichia.unclassified
2021-05-06 04:16:26 INFO::Fitting model to feature number 84, Klebsiella.pneumoniae
2021-05-06 04:16:26 INFO::Fitting model to feature number 85, Haemophilus.parainfluenzae
2021-05-06 04:16:26 INFO::Fitting model to feature number 86, Akkermansia.muciniphila
2021-05-06 04:16:26 INFO::Fitting model to feature number 87, C2likevirus.unclassified
2021-05-06 04:16:26 INFO::Counting total values for each feature
2021-05-06 04:16:26 INFO::Writing residuals to file output2/residuals.rds
2021-05-06 04:16:27 INFO::Writing all results to file (ordered by increasing q-values): output2/all_results.tsv
2021-05-06 04:16:27 INFO::Writing the significant results (those which are less than or equal to the threshold of 0.250000 ) to file (ordered by increasing q-values): output2/significant_results.tsv
[ FAIL 0 | WARN 5 | SKIP 0 | PASS 12 ]
>
>
> proc.time()
user system elapsed
42.51 0.39 42.89
|
Maaslin2.Rcheck/tests_x64/testthat.Rout
R version 4.0.5 (2021-03-31) -- "Shake and Throw"
Copyright (C) 2021 The R Foundation for Statistical Computing
Platform: x86_64-w64-mingw32/x64 (64-bit)
R is free software and comes with ABSOLUTELY NO WARRANTY.
You are welcome to redistribute it under certain conditions.
Type 'license()' or 'licence()' for distribution details.
R is a collaborative project with many contributors.
Type 'contributors()' for more information and
'citation()' on how to cite R or R packages in publications.
Type 'demo()' for some demos, 'help()' for on-line help, or
'help.start()' for an HTML browser interface to help.
Type 'q()' to quit R.
> library(testthat)
> library(Maaslin2)
>
> test_check("Maaslin2")
[1] "Creating output folder"
2021-05-06 04:16:29 INFO::Writing function arguments to log file
2021-05-06 04:16:29 INFO::Verifying options selected are valid
2021-05-06 04:16:29 INFO::Determining format of input files
2021-05-06 04:16:29 INFO::Input format is data samples as rows and metadata samples as rows
2021-05-06 04:16:29 INFO::Formula for random effects: expr ~ (1 | site) + (1 | subject)
2021-05-06 04:16:29 INFO::Formula for fixed effects: expr ~ diagnosis + dysbiosisnonIBD + dysbiosisUC + dysbiosisCD + antibiotics + age
2021-05-06 04:16:29 INFO::Filter data based on min abundance and min prevalence
2021-05-06 04:16:29 INFO::Total samples in data: 1595
2021-05-06 04:16:29 INFO::Min samples required with min abundance for a feature not to be filtered: 159.500000
2021-05-06 04:16:29 INFO::Total filtered features: 0
2021-05-06 04:16:29 INFO::Filtered feature names from abundance and prevalence filtering:
2021-05-06 04:16:29 INFO::Running selected normalization method: TSS
2021-05-06 04:16:31 INFO::Total filtered features with variance filtering: 0
2021-05-06 04:16:31 INFO::Filtered feature names from variance filtering:
2021-05-06 04:16:31 INFO::Bypass z-score application to metadata
2021-05-06 04:16:31 INFO::Running selected transform method: AST
2021-05-06 04:16:31 INFO::Running selected analysis method: LM
2021-05-06 04:16:31 INFO::Fitting model to feature number 1, Bifidobacterium.adolescentis
2021-05-06 04:16:33 INFO::Fitting model to feature number 2, Bifidobacterium.bifidum
2021-05-06 04:16:33 INFO::Fitting model to feature number 3, Bifidobacterium.longum
2021-05-06 04:16:33 INFO::Fitting model to feature number 4, Bifidobacterium.pseudocatenulatum
2021-05-06 04:16:33 INFO::Fitting model to feature number 5, Collinsella.aerofaciens
2021-05-06 04:16:34 INFO::Fitting model to feature number 6, Bacteroides.caccae
2021-05-06 04:16:34 INFO::Fitting model to feature number 7, Bacteroides.cellulosilyticus
2021-05-06 04:16:34 INFO::Fitting model to feature number 8, Bacteroides.dorei
2021-05-06 04:16:34 INFO::Fitting model to feature number 9, Bacteroides.eggerthii
2021-05-06 04:16:34 INFO::Fitting model to feature number 10, Bacteroides.faecis
2021-05-06 04:16:35 INFO::Fitting model to feature number 11, Bacteroides.finegoldii
2021-05-06 04:16:35 INFO::Fitting model to feature number 12, Bacteroides.fragilis
2021-05-06 04:16:35 INFO::Fitting model to feature number 13, Bacteroides.intestinalis
2021-05-06 04:16:35 INFO::Fitting model to feature number 14, Bacteroides.massiliensis
2021-05-06 04:16:35 INFO::Fitting model to feature number 15, Bacteroides.ovatus
2021-05-06 04:16:36 INFO::Fitting model to feature number 16, Bacteroides.salyersiae
2021-05-06 04:16:36 INFO::Fitting model to feature number 17, Bacteroides.stercoris
2021-05-06 04:16:36 INFO::Fitting model to feature number 18, Bacteroides.thetaiotaomicron
2021-05-06 04:16:36 INFO::Fitting model to feature number 19, Bacteroides.uniformis
2021-05-06 04:16:36 INFO::Fitting model to feature number 20, Bacteroides.vulgatus
2021-05-06 04:16:37 INFO::Fitting model to feature number 21, Bacteroides.xylanisolvens
2021-05-06 04:16:37 INFO::Fitting model to feature number 22, Bacteroidales.bacterium.ph8
2021-05-06 04:16:37 INFO::Fitting model to feature number 23, Barnesiella.intestinihominis
2021-05-06 04:16:37 INFO::Fitting model to feature number 24, Coprobacter.fastidiosus
2021-05-06 04:16:37 INFO::Fitting model to feature number 25, Odoribacter.splanchnicus
2021-05-06 04:16:38 INFO::Fitting model to feature number 26, Parabacteroides.distasonis
2021-05-06 04:16:38 INFO::Fitting model to feature number 27, Parabacteroides.goldsteinii
2021-05-06 04:16:38 INFO::Fitting model to feature number 28, Parabacteroides.merdae
2021-05-06 04:16:38 INFO::Fitting model to feature number 29, Parabacteroides.unclassified
2021-05-06 04:16:38 INFO::Fitting model to feature number 30, Paraprevotella.clara
2021-05-06 04:16:39 INFO::Fitting model to feature number 31, Paraprevotella.unclassified
2021-05-06 04:16:39 INFO::Fitting model to feature number 32, Prevotella.copri
2021-05-06 04:16:39 INFO::Fitting model to feature number 33, Alistipes.finegoldii
2021-05-06 04:16:39 INFO::Fitting model to feature number 34, Alistipes.onderdonkii
2021-05-06 04:16:39 INFO::Fitting model to feature number 35, Alistipes.putredinis
2021-05-06 04:16:40 INFO::Fitting model to feature number 36, Alistipes.shahii
2021-05-06 04:16:40 INFO::Fitting model to feature number 37, Alistipes.unclassified
2021-05-06 04:16:40 INFO::Fitting model to feature number 38, Streptococcus.salivarius
2021-05-06 04:16:40 INFO::Fitting model to feature number 39, Clostridium.bolteae
2021-05-06 04:16:40 INFO::Fitting model to feature number 40, Clostridium.citroniae
2021-05-06 04:16:40 INFO::Fitting model to feature number 41, Clostridium.clostridioforme
2021-05-06 04:16:41 INFO::Fitting model to feature number 42, Clostridium.hathewayi
2021-05-06 04:16:41 INFO::Fitting model to feature number 43, Clostridium.leptum
2021-05-06 04:16:41 INFO::Fitting model to feature number 44, Clostridium.nexile
2021-05-06 04:16:41 INFO::Fitting model to feature number 45, Clostridium.symbiosum
2021-05-06 04:16:41 INFO::Fitting model to feature number 46, Flavonifractor.plautii
2021-05-06 04:16:42 INFO::Fitting model to feature number 47, Eubacterium.eligens
2021-05-06 04:16:42 INFO::Fitting model to feature number 48, Eubacterium.hallii
2021-05-06 04:16:42 INFO::Fitting model to feature number 49, Eubacterium.rectale
2021-05-06 04:16:42 INFO::Fitting model to feature number 50, Eubacterium.siraeum
2021-05-06 04:16:42 INFO::Fitting model to feature number 51, Eubacterium.sp.3.1.31
2021-05-06 04:16:43 INFO::Fitting model to feature number 52, Eubacterium.ventriosum
2021-05-06 04:16:43 INFO::Fitting model to feature number 53, Ruminococcus.gnavus
2021-05-06 04:16:43 INFO::Fitting model to feature number 54, Ruminococcus.obeum
2021-05-06 04:16:43 INFO::Fitting model to feature number 55, Ruminococcus.torques
2021-05-06 04:16:43 INFO::Fitting model to feature number 56, Coprococcus.comes
2021-05-06 04:16:44 INFO::Fitting model to feature number 57, Dorea.longicatena
2021-05-06 04:16:44 INFO::Fitting model to feature number 58, Lachnospiraceae.bacterium.1.1.57FAA
2021-05-06 04:16:44 INFO::Fitting model to feature number 59, Lachnospiraceae.bacterium.3.1.46FAA
2021-05-06 04:16:44 INFO::Fitting model to feature number 60, Roseburia.hominis
2021-05-06 04:16:44 INFO::Fitting model to feature number 61, Roseburia.intestinalis
2021-05-06 04:16:44 INFO::Fitting model to feature number 62, Roseburia.inulinivorans
2021-05-06 04:16:45 INFO::Fitting model to feature number 63, Roseburia.unclassified
2021-05-06 04:16:45 INFO::Fitting model to feature number 64, Oscillibacter.unclassified
2021-05-06 04:16:45 INFO::Fitting model to feature number 65, Peptostreptococcaceae.noname.unclassified
2021-05-06 04:16:45 INFO::Fitting model to feature number 66, Faecalibacterium.prausnitzii
2021-05-06 04:16:46 INFO::Fitting model to feature number 67, Ruminococcus.bromii
2021-05-06 04:16:46 INFO::Fitting model to feature number 68, Ruminococcus.callidus
2021-05-06 04:16:46 INFO::Fitting model to feature number 69, Ruminococcus.lactaris
2021-05-06 04:16:46 INFO::Fitting model to feature number 70, Subdoligranulum.unclassified
2021-05-06 04:16:47 INFO::Fitting model to feature number 71, Coprobacillus.unclassified
2021-05-06 04:16:47 INFO::Fitting model to feature number 72, Acidaminococcus.unclassified
2021-05-06 04:16:47 INFO::Fitting model to feature number 73, Dialister.invisus
2021-05-06 04:16:47 INFO::Fitting model to feature number 74, Veillonella.atypica
2021-05-06 04:16:47 INFO::Fitting model to feature number 75, Veillonella.dispar
2021-05-06 04:16:47 INFO::Fitting model to feature number 76, Veillonella.parvula
2021-05-06 04:16:48 INFO::Fitting model to feature number 77, Veillonella.unclassified
2021-05-06 04:16:48 INFO::Fitting model to feature number 78, Burkholderiales.bacterium.1.1.47
2021-05-06 04:16:48 INFO::Fitting model to feature number 79, Parasutterella.excrementihominis
2021-05-06 04:16:48 INFO::Fitting model to feature number 80, Sutterella.wadsworthensis
2021-05-06 04:16:48 INFO::Fitting model to feature number 81, Bilophila.unclassified
2021-05-06 04:16:48 INFO::Fitting model to feature number 82, Escherichia.coli
2021-05-06 04:16:49 INFO::Fitting model to feature number 83, Escherichia.unclassified
2021-05-06 04:16:49 INFO::Fitting model to feature number 84, Klebsiella.pneumoniae
2021-05-06 04:16:49 INFO::Fitting model to feature number 85, Haemophilus.parainfluenzae
2021-05-06 04:16:49 INFO::Fitting model to feature number 86, Akkermansia.muciniphila
2021-05-06 04:16:50 INFO::Fitting model to feature number 87, C2likevirus.unclassified
2021-05-06 04:16:50 INFO::Counting total values for each feature
2021-05-06 04:16:50 INFO::Writing residuals to file output/residuals.rds
2021-05-06 04:16:50 INFO::Writing all results to file (ordered by increasing q-values): output/all_results.tsv
2021-05-06 04:16:50 INFO::Writing the significant results (those which are less than or equal to the threshold of 0.250000 ) to file (ordered by increasing q-values): output/significant_results.tsv
[1] "Creating output folder"
2021-05-06 04:16:50 INFO::Writing function arguments to log file
2021-05-06 04:16:50 INFO::Verifying options selected are valid
2021-05-06 04:16:50 INFO::Determining format of input files
2021-05-06 04:16:50 INFO::Input format is data samples as rows and metadata samples as rows
2021-05-06 04:16:50 INFO::Formula for random effects: expr ~ (1 | site) + (1 | subject)
2021-05-06 04:16:50 INFO::Formula for fixed effects: expr ~ diagnosis + dysbiosis + antibiotics + age
2021-05-06 04:16:50 INFO::Filter data based on min abundance and min prevalence
2021-05-06 04:16:50 INFO::Total samples in data: 1595
2021-05-06 04:16:50 INFO::Min samples required with min abundance for a feature not to be filtered: 159.500000
2021-05-06 04:16:50 INFO::Total filtered features: 0
2021-05-06 04:16:50 INFO::Filtered feature names from abundance and prevalence filtering:
2021-05-06 04:16:50 INFO::Running selected normalization method: NONE
2021-05-06 04:16:50 INFO::Total filtered features with variance filtering: 0
2021-05-06 04:16:50 INFO::Filtered feature names from variance filtering:
2021-05-06 04:16:50 INFO::Bypass z-score application to metadata
2021-05-06 04:16:50 INFO::Running selected transform method: AST
2021-05-06 04:16:50 INFO::Running selected analysis method: LM
2021-05-06 04:16:50 INFO::Fitting model to feature number 1, Bifidobacterium.adolescentis
2021-05-06 04:16:50 INFO::Fitting model to feature number 2, Bifidobacterium.bifidum
2021-05-06 04:16:51 INFO::Fitting model to feature number 3, Bifidobacterium.longum
2021-05-06 04:16:51 INFO::Fitting model to feature number 4, Bifidobacterium.pseudocatenulatum
2021-05-06 04:16:51 INFO::Fitting model to feature number 5, Collinsella.aerofaciens
2021-05-06 04:16:51 INFO::Fitting model to feature number 6, Bacteroides.caccae
2021-05-06 04:16:51 INFO::Fitting model to feature number 7, Bacteroides.cellulosilyticus
2021-05-06 04:16:52 INFO::Fitting model to feature number 8, Bacteroides.dorei
2021-05-06 04:16:52 INFO::Fitting model to feature number 9, Bacteroides.eggerthii
2021-05-06 04:16:52 INFO::Fitting model to feature number 10, Bacteroides.faecis
2021-05-06 04:16:52 INFO::Fitting model to feature number 11, Bacteroides.finegoldii
2021-05-06 04:16:52 INFO::Fitting model to feature number 12, Bacteroides.fragilis
2021-05-06 04:16:53 INFO::Fitting model to feature number 13, Bacteroides.intestinalis
2021-05-06 04:16:53 INFO::Fitting model to feature number 14, Bacteroides.massiliensis
2021-05-06 04:16:53 INFO::Fitting model to feature number 15, Bacteroides.ovatus
2021-05-06 04:16:53 INFO::Fitting model to feature number 16, Bacteroides.salyersiae
2021-05-06 04:16:54 INFO::Fitting model to feature number 17, Bacteroides.stercoris
2021-05-06 04:16:54 INFO::Fitting model to feature number 18, Bacteroides.thetaiotaomicron
2021-05-06 04:16:54 INFO::Fitting model to feature number 19, Bacteroides.uniformis
2021-05-06 04:16:54 INFO::Fitting model to feature number 20, Bacteroides.vulgatus
2021-05-06 04:16:54 INFO::Fitting model to feature number 21, Bacteroides.xylanisolvens
2021-05-06 04:16:55 INFO::Fitting model to feature number 22, Bacteroidales.bacterium.ph8
2021-05-06 04:16:55 INFO::Fitting model to feature number 23, Barnesiella.intestinihominis
2021-05-06 04:16:55 INFO::Fitting model to feature number 24, Coprobacter.fastidiosus
2021-05-06 04:16:55 INFO::Fitting model to feature number 25, Odoribacter.splanchnicus
2021-05-06 04:16:55 INFO::Fitting model to feature number 26, Parabacteroides.distasonis
2021-05-06 04:16:56 INFO::Fitting model to feature number 27, Parabacteroides.goldsteinii
2021-05-06 04:16:56 INFO::Fitting model to feature number 28, Parabacteroides.merdae
2021-05-06 04:16:56 INFO::Fitting model to feature number 29, Parabacteroides.unclassified
2021-05-06 04:16:56 INFO::Fitting model to feature number 30, Paraprevotella.clara
2021-05-06 04:16:56 INFO::Fitting model to feature number 31, Paraprevotella.unclassified
2021-05-06 04:16:56 INFO::Fitting model to feature number 32, Prevotella.copri
2021-05-06 04:16:57 INFO::Fitting model to feature number 33, Alistipes.finegoldii
2021-05-06 04:16:57 INFO::Fitting model to feature number 34, Alistipes.onderdonkii
2021-05-06 04:16:57 INFO::Fitting model to feature number 35, Alistipes.putredinis
2021-05-06 04:16:57 INFO::Fitting model to feature number 36, Alistipes.shahii
2021-05-06 04:16:57 INFO::Fitting model to feature number 37, Alistipes.unclassified
2021-05-06 04:16:58 INFO::Fitting model to feature number 38, Streptococcus.salivarius
2021-05-06 04:16:58 INFO::Fitting model to feature number 39, Clostridium.bolteae
2021-05-06 04:16:58 INFO::Fitting model to feature number 40, Clostridium.citroniae
2021-05-06 04:16:58 INFO::Fitting model to feature number 41, Clostridium.clostridioforme
2021-05-06 04:16:58 INFO::Fitting model to feature number 42, Clostridium.hathewayi
2021-05-06 04:16:58 INFO::Fitting model to feature number 43, Clostridium.leptum
2021-05-06 04:16:59 INFO::Fitting model to feature number 44, Clostridium.nexile
2021-05-06 04:16:59 INFO::Fitting model to feature number 45, Clostridium.symbiosum
2021-05-06 04:16:59 INFO::Fitting model to feature number 46, Flavonifractor.plautii
2021-05-06 04:16:59 INFO::Fitting model to feature number 47, Eubacterium.eligens
2021-05-06 04:17:00 INFO::Fitting model to feature number 48, Eubacterium.hallii
2021-05-06 04:17:00 INFO::Fitting model to feature number 49, Eubacterium.rectale
2021-05-06 04:17:00 INFO::Fitting model to feature number 50, Eubacterium.siraeum
2021-05-06 04:17:00 INFO::Fitting model to feature number 51, Eubacterium.sp.3.1.31
2021-05-06 04:17:01 INFO::Fitting model to feature number 52, Eubacterium.ventriosum
2021-05-06 04:17:01 INFO::Fitting model to feature number 53, Ruminococcus.gnavus
2021-05-06 04:17:01 INFO::Fitting model to feature number 54, Ruminococcus.obeum
2021-05-06 04:17:01 INFO::Fitting model to feature number 55, Ruminococcus.torques
2021-05-06 04:17:01 INFO::Fitting model to feature number 56, Coprococcus.comes
2021-05-06 04:17:02 INFO::Fitting model to feature number 57, Dorea.longicatena
2021-05-06 04:17:02 INFO::Fitting model to feature number 58, Lachnospiraceae.bacterium.1.1.57FAA
2021-05-06 04:17:02 INFO::Fitting model to feature number 59, Lachnospiraceae.bacterium.3.1.46FAA
2021-05-06 04:17:02 INFO::Fitting model to feature number 60, Roseburia.hominis
2021-05-06 04:17:02 INFO::Fitting model to feature number 61, Roseburia.intestinalis
2021-05-06 04:17:02 INFO::Fitting model to feature number 62, Roseburia.inulinivorans
2021-05-06 04:17:03 INFO::Fitting model to feature number 63, Roseburia.unclassified
2021-05-06 04:17:03 INFO::Fitting model to feature number 64, Oscillibacter.unclassified
2021-05-06 04:17:03 INFO::Fitting model to feature number 65, Peptostreptococcaceae.noname.unclassified
2021-05-06 04:17:03 INFO::Fitting model to feature number 66, Faecalibacterium.prausnitzii
2021-05-06 04:17:03 INFO::Fitting model to feature number 67, Ruminococcus.bromii
2021-05-06 04:17:03 INFO::Fitting model to feature number 68, Ruminococcus.callidus
2021-05-06 04:17:03 INFO::Fitting model to feature number 69, Ruminococcus.lactaris
2021-05-06 04:17:04 INFO::Fitting model to feature number 70, Subdoligranulum.unclassified
2021-05-06 04:17:04 INFO::Fitting model to feature number 71, Coprobacillus.unclassified
2021-05-06 04:17:04 INFO::Fitting model to feature number 72, Acidaminococcus.unclassified
2021-05-06 04:17:04 INFO::Fitting model to feature number 73, Dialister.invisus
2021-05-06 04:17:04 INFO::Fitting model to feature number 74, Veillonella.atypica
2021-05-06 04:17:04 INFO::Fitting model to feature number 75, Veillonella.dispar
2021-05-06 04:17:05 INFO::Fitting model to feature number 76, Veillonella.parvula
2021-05-06 04:17:05 INFO::Fitting model to feature number 77, Veillonella.unclassified
2021-05-06 04:17:05 INFO::Fitting model to feature number 78, Burkholderiales.bacterium.1.1.47
2021-05-06 04:17:05 INFO::Fitting model to feature number 79, Parasutterella.excrementihominis
2021-05-06 04:17:05 INFO::Fitting model to feature number 80, Sutterella.wadsworthensis
2021-05-06 04:17:05 INFO::Fitting model to feature number 81, Bilophila.unclassified
2021-05-06 04:17:06 INFO::Fitting model to feature number 82, Escherichia.coli
2021-05-06 04:17:06 INFO::Fitting model to feature number 83, Escherichia.unclassified
2021-05-06 04:17:06 INFO::Fitting model to feature number 84, Klebsiella.pneumoniae
2021-05-06 04:17:06 INFO::Fitting model to feature number 85, Haemophilus.parainfluenzae
2021-05-06 04:17:06 INFO::Fitting model to feature number 86, Akkermansia.muciniphila
2021-05-06 04:17:06 INFO::Fitting model to feature number 87, C2likevirus.unclassified
2021-05-06 04:17:07 INFO::Counting total values for each feature
2021-05-06 04:17:07 INFO::Writing residuals to file output2/residuals.rds
2021-05-06 04:17:07 INFO::Writing all results to file (ordered by increasing q-values): output2/all_results.tsv
2021-05-06 04:17:07 INFO::Writing the significant results (those which are less than or equal to the threshold of 0.250000 ) to file (ordered by increasing q-values): output2/significant_results.tsv
[ FAIL 0 | WARN 6 | SKIP 0 | PASS 12 ]
>
>
> proc.time()
user system elapsed
39.48 0.37 39.89
|