Bioconductor release scheduled for October 29

markeR

This is the development version of markeR; to use it, please install the devel version of Bioconductor.

An R Toolkit for Evaluating Gene Signatures as Phenotypic Markers


Bioconductor version: Development (3.22)

A suite of methods for using gene sets to quantify and evaluate the extent to which a given gene signature marks a specific phenotype. The package implements various scoring, enrichment and classification approaches, along with tools to compute performance metrics and visualize results, making it a valuable resource for transcriptomics research (bulk RNA-seq).

Author: Rita Martins-Silva [aut, cre] ORCID iD ORCID: 0000-0002-1067-7993 , Alexandre Kaizeler [aut, ctb] ORCID iD ORCID: 0000-0002-9117-6073 , Nuno Luís Barbosa-Morais [aut, led, ths] ORCID iD ORCID: 0000-0002-1215-0538

Maintainer: Rita Martins-Silva <rita.silva at medicina.ulisboa.pt>

Citation (from within R, enter citation("markeR")):

Installation

To install this package, start R (version "4.5") and enter:


if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

# The following initializes usage of Bioc devel
BiocManager::install(version='devel')

BiocManager::install("markeR")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("markeR")
Introduction to markeR HTML R Script
Reference Manual PDF

Details

biocViews Classification, GeneExpression, GeneSetEnrichment, Software, Transcriptomics, Visualization
Version 0.99.5
In Bioconductor since BioC 3.22 (R-4.5)
License Artistic-2.0
Depends R (>= 4.5.0)
Imports circlize, edgeR, ComplexHeatmap, ggh4x, ggplot2, ggpubr, grid, gridExtra, pROC, RColorBrewer, reshape2, rstatix, scales, stats, utils, fgsea, limma, ggrepel, effectsize, msigdbr, tibble
System Requirements
URL https://diseasetranscriptomicslab.github.io/markeR/ https://github.com/DiseaseTranscriptomicsLab/markeR
Bug Reports https://github.com/DiseaseTranscriptomicsLab/markeR/issues
See More
Suggests devtools, markdown, renv, testthat, BiocManager, knitr, rmarkdown, roxygen2, mockery, covr, magick, BiocStyle
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Build Report Build Report

Package Archives

Follow Installation instructions to use this package in your R session.

Source Package markeR_0.99.5.tar.gz
Windows Binary (x86_64)
macOS Binary (x86_64) markeR_0.99.5.tgz
macOS Binary (arm64) markeR_0.99.5.tgz
Source Repository git clone https://git.bioconductor.org/packages/markeR
Source Repository (Developer Access) git clone git@git.bioconductor.org:packages/markeR
Bioc Package Browser https://code.bioconductor.org/browse/markeR/
Package Short Url https://bioconductor.org/packages/markeR/
Package Downloads Report Download Stats