dominoSignal
This is the development version of dominoSignal; for the stable release version, see dominoSignal.
Cell Communication Analysis for Single Cell RNA Sequencing
Bioconductor version: Development (3.23)
dominoSignal is a package developed to analyze cell signaling through ligand - receptor - transcription factor networks in scRNAseq data. It takes as input information transcriptomic data, requiring counts, z-scored counts, and cluster labels, as well as information on transcription factor activation (such as from SCENIC) and a database of ligand and receptor pairings (such as from CellPhoneDB). This package creates an object storing ligand - receptor - transcription factor linkages by cluster and provides several methods for exploring, summarizing, and visualizing the analysis.
Author: Christopher Cherry [aut]
, Jacob T Mitchell [aut, cre]
, Sushma Nagaraj [aut]
, Kavita Krishnan [aut]
, Dmitrijs Lvovs [aut], Elana Fertig [ctb]
, Jennifer Elisseeff [ctb]
Maintainer: Jacob T Mitchell <jmitch81 at jhmi.edu>
citation("dominoSignal")):
Installation
To install this package, start R (version "4.6") and enter:
if (!require("BiocManager", quietly = TRUE))
install.packages("BiocManager")
# The following initializes usage of Bioc devel
BiocManager::install(version='devel')
BiocManager::install("dominoSignal")
For older versions of R, please refer to the appropriate Bioconductor release.
Documentation
| Reference Manual |
Details
| biocViews | Network, SingleCell, Software, SystemsBiology, Transcriptomics |
| Version | 1.5.0 |
| In Bioconductor since | BioC 3.20 (R-4.4) (1 year) |
| License | GPL-3 | file LICENSE |
| Depends | R (>= 4.2.0) |
| Imports | biomaRt, ComplexHeatmap, circlize, ggpubr, grDevices, grid, igraph, Matrix, methods, plyr, stats, utils, magrittr, purrr, dplyr |
| System Requirements | |
| URL | https://fertiglab.github.io/dominoSignal/ |
| Bug Reports | https://github.com/FertigLab/dominoSignal/issues |
See More
| Suggests | knitr, patchwork, rmarkdown, Seurat, testthat, formatR, BiocFileCache, SingleCellExperiment |
| Linking To | |
| Enhances | |
| Depends On Me | |
| Imports Me | |
| Suggests Me | |
| Links To Me | |
| Build Report | Build Report |
Package Archives
Follow Installation instructions to use this package in your R session.
| Source Package | |
| Windows Binary (x86_64) | |
| macOS Binary (x86_64) | |
| macOS Binary (arm64) | |
| Source Repository | git clone https://git.bioconductor.org/packages/dominoSignal |
| Source Repository (Developer Access) | git clone git@git.bioconductor.org:packages/dominoSignal |
| Package Short Url | https://bioconductor.org/packages/dominoSignal/ |
| Package Downloads Report | Download Stats |