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<br>

# TF ranking plot
TF ranking plot shows statistic $-log_{10}(P value)$ assessing the anti-correlation level 
of TFs expression level with average DNA methylation level at sites with a given motif. 
By default, the top 3 associated TFs and the TF family members (dots in red) that are associated with that specific motif  are labeled in the plot.
But there is also a option show highlight only TF sub-family members (TCClass database classification)

## TF ranking plot: family classification

Shown are TF ranking plots based on the score ($-log_{10}(P value))$ of association between TF expression and DNA methylation of an enriched motif in the LUSC cancer type. The dashed line indicates the boundary of the top 5% association score. The top 3 associated TFs and the TF family members=(dots in red) that are associated with that specific motif are labeled in the plot

```{r,eval=TRUE,fig.cap="Shown are TF ranking plots based on the score (-log(P value)) of association between TF expression and DNA methylation of the enriched motif in the LUSC cancer type. The dashed line indicates the boundary of the top 5% association score. The top 3 associated TFs and the TF family members=(dots in red) that are associated with that specific motif are labeled in the plot"}
load("result/getTF.hypo.TFs.with.motif.pvalue.rda")
motif <- colnames(TF.meth.cor)[1]
TF.rank.plot(motif.pvalue = TF.meth.cor, 
             motif = motif,
             save = FALSE) 
```