Changes in version 1.4.0                        

  - Add functionality to process SCE objects for PCA computation via the
    new processPCA function.
  - Add functionality to downsample SCE objects for diagnostic
    functions.
  - Add new diagnostic functions (calculateTopLoadingGeneShifts,
    compareMarkers and calculateMMDPValue).
  - Add graph integration diagnostic function in replacement of nearest
    neighbor diagnostic, calculateGraphIntegration.
  - Improve regressPC function and plot method, which can now also
    regress against cell types and batches.
  - Improve normalization for plotMarkerExpression diagnostic function.
  - Improve user control and options for plot methods.
  - Update vignettes to reflect all new changes.

                        Changes in version 1.0.0                        

  - Initial release of the scDiagnostics package.