Changes in version 0.99.18 - Remove estiParamTwoGroups() so users only use estiParam() for parameter estimation. - Updated the workflow as shown in the vignetee. Changes in version 0.99.16 - Added BPPARAM arguments. - sapply() to vapply(). Changes in version 0.99.14 - Improved the efficiency of functions. Changes in version 0.99.13 - Added ggplot2 check in plotGene(). Changes in version 0.99.11 - Added URL and BugReports fields in DESCRIPTION. - Moved ggplot2 to Suggests. - Updated BiocStyle in Vignettes. - Added .man pages for example data. - Added verbose arguments to functions for users to control message printing. - Added BPPARAM = SnowParam() to bplapply() used in functions. - Updated functions to use the sce object as both the input and ouput.