\name{mclusterSim} \alias{mclusterSim} \title{Pairwise Semantic Similarities for a List of Gene Clusters} \description{ Given a list of gene clusters, this function calculates pairwise semantic similarities. } \usage{ mclusterSim(clusters, ont = "MF", organism="human", measure="Wang", drop= "IEA") } \arguments{ \item{clusters}{A list of gene clusters. } \item{ont}{One of "MF", "BP", and "CC" subontologies.} \item{measure}{One of "Resnik", "Lin", "Rel", "Jiang" and "Wang" methods.} \item{organism}{One of "human", "rat", "mouse", "fly" and "yeast".} \item{drop}{A set of evidence codes based on which certain annotations are dropped. Use NULL to keep all GO annotations.} } \value{ \item{simmat }{A Matrix of Pairwise Semantic Similarities} } \seealso{ \code{\link{goSim}} \code{\link{mgoSim}} \code{\link{geneSim}} \code{\link{mgeneSim}} \code{\link{clusterSim}} } \examples{ cluster1 <- c("snR67","snR40","snR48", "snR17a","snR8") cluster2 <- c("YOR251C", "YPR137C-B", "YPR010C", "YPR072W") cluster3 <- c("YNL133C", "YOL041C", "YOL018C", "YOR236W", "YOR179C", "YOR230W") clusters <- list(a=cluster1, b=cluster2, c=cluster3) mclusterSim(clusters, ont="MF", organism="yeast", measure="Wang") } \references{ Wang et al.(2007) A new method to measure the semantic similarity of go terms \emph{Bioinformatics} (Oxford, England), 23:0 1274--81, May 2007. ISSN 1460-2059 \url{http://www.ncbi.nlm.nih.gov/pubmed/17344234} PMID: 17344234 P W Lord et al.(2003) Semantic similarity measures as tools for exploring the gene ontology \url{Pacific Symposium on Biocomputing} Pacific Symposium on Biocomputing, 2003:601-12, ISSN 1793-5091 \url{http://www.ncbi.nlm.nih.gov/pubmed/12603061} PMID: 12603061 } \keyword{ manip}