\name{normalize.ExpressionSet.nordi} \alias{normalize.ExpressionSet.nordi} %- Also NEED an '\alias' for EACH other topic documented here. \title{ normal discretization normalization } \description{ Performs a discretization of continous expression levels to discrete steps. } \usage{ normalize.ExpressionSet.nordi(ExpressionSet = NULL, pvalue = 0.01, alpha = 0.05) } \arguments{ \item{ExpressionSet}{ An ExpressionSet object } \item{pvalue}{ The pvalue determines the sensitivity for detecting outliers in each column of the gene expression matrix. } \item{alpha}{ The alpha value determines the size of the tails of the normal distributions considered to be over or under expressed. } } \details{ %% ~~ If necessary, more details than the description above ~~ Please see the references for details. } \value{ An ExpressionSet object with adjusted expression matrix. } \references{ "GenMiner: Mining informative association rules from genomic data." Ricardo Martinez, Claude Pasquier and Nicolas Pasquier, Proceedings of the IEEE BIBM international conference on Bioinformatics and Biomedecine, pages 15-22, IEEE Computer Society, 2007. Martinez R, Pasquier N, Pasquier C: GenMiner: mining non-redundant association rules from integrated gene expression data and annotations. Bioinformatics 2008, 24:2643-2644.} \author{ Andreas Heider } \note{ %% ~~further notes~~ } %% ~Make other sections like Warning with \section{Warning }{....} ~ \seealso{ %% ~~objects to See Also as \code{\link{help}}, ~~~ virtualArrayExpressionSets } \examples{ # library(affydata) # data(Dilution) # Dilution <- rma(Dilution) # normalize.ExpressionSet.nordi(Dilution) } % Add one or more standard keywords, see file 'KEYWORDS' in the % R documentation directory. \keyword{ virtualArray } \keyword{ batch effect removal } \keyword{ normalization } \keyword{ cross-platform }