\name{CellNOptR-package} \alias{CellNOptR-package} \alias{CellNOptR} \docType{package} \title{ R version of CellNOptR, boolean features } \description{ This package does optimisation of boolean logic networks of signalling pathways based on a previous knowledge network and a set of data collected upon perturbation of some of the nodes in the network. } \details{ \tabular{ll}{ Package: \tab CellNOptR\cr Type: \tab Package\cr Version: \tab 1.1.2\cr Date: \tab 2011-03-31\cr License: \tab GPLv2\cr LazyLoad: \tab yes\cr } } \author{ C.Terfve, T.Cokelaer Maintainer: C.Terfve } \references{ J. Saez-Rodriguez, L. G. Alexopoulos, J. Epperlein, R. Samaga, D. A. Lauffenburger, S. Klamt and P. K. Sorger. Discrete logic modeling as a means to link protein signaling networks with functional analysis of mammalian signal transduction, Molecular Systems Biology, 5:331, 2009. } \keyword{ package } \examples{ library(CellNOptR) tmpdir<-tempdir() setwd(tmpdir) data(CNOlistToy,package="CellNOptR") data(ToyModel,package="CellNOptR") #From here there are 2 versions: 1. If you want to set the parameters yourself pList<-list( Data=CNOlistToy, Model=ToyModel, sizeFac = 1e-04, NAFac = 1, PopSize = 10, Pmutation = 0.5, MaxTime = 60, maxGens = 5, StallGenMax = 5, SelPress = 1.2, elitism = 5, RelTol = 0.1, verbose=TRUE) CNORwrap( paramsList=pList, Name="Toy", NamesData=list(CNOlist="ToyData",Model="ToyModel"), Data=NA, Model=NA) #2. If you want to keep the default parameters \dontrun{ CNORwrap( paramsList=NA, Name="Toy", NamesData=list(CNOlist="ToyData",Model="ToyModel"), Data=CNOlistToy, Model=ToyModel) } }