\name{hmyriB36} \docType{package} \alias{hmyriB36} \alias{hmyriB36-package} \alias{ex} \title{representations of HapMap phaseII snp data + expression data} \description{ representations of HapMap snp data + expression data } \format{ExpressionSet and SnpMatrix instances to be combined using getSS} \usage{ # getSS("hmyriB36", "20") # for example, to get full expression, + genotypes # on chr20 } \details{ Instances of class \code{\link[GGBase:smlSet-class]{smlSet}} are created from two basic sources. First, the expression data for 90 YRI families were obtained from SANGER GENEVAR project. Second, data on forward non-redundant SNPs in these individuals the HapMap build 36 ftp site (r23a) in march 2008. Full provenance information still to be supplied. } \value{ instances of class \code{\link[GGBase:smlSet-class]{smlSet}} } \references{ Cheung VG., Spielman RS., Ewens KG., Weber TM., Morley M & Burdick JT.: \emph{Mapping determinants of human gene expression by regional and whole genome association.} Nature, 437: 1365-1369, 2005 } \author{Vince Carey } \note{ As of March 2011 the smlSet is no longer serialized. Instead, use \code{getSS("hmyriB36", [chrs])} to create an smlSet with all probes and selected chromosomes. There is an instance of \code{\link[Biobase]{ExpressionSet-class}} named \code{ex} in the \code{data} folder of this package that will be united with genotype data using \code{\link[GGBase]{getSS}}. } %\seealso{ } \examples{ library(GGtools) hmyriB36 = getSS("hmyriB36", c("20")) # just 1 chromosome exprs(hmyriB36)[1:4,1:4] as(smList(hmyriB36)[[1]][1:4,1:4], "character") library(GGtools) library(illuminaHumanv1.db) cptag = get("CPNE1", revmap(illuminaHumanv1SYMBOL)) tt = eqtlTests(hmyriB36[probeId(cptag),] , ~male) topFeats(probeId(cptag), mgr=tt, ffind=1) } \keyword{ packages }