\name{GCAdjustParams} \docType{class} \alias{GCAdjustParams} \alias{GCAdjustParams-class} \alias{GCAdjustParams,BSgenome,BSgenome-method} \title{Container for parameters for mappability and GC content adjusted absolute copy number estimation.} \description{ The parameters are used by the \code{\link{absoluteCN}} function. } \section{Constructor}{ \describe{ \item{}{ \code{GCAdjustParams(genome, mappability, min.mappability, n.bins = NULL, min.bin.size = 1, poly.degree = NULL, ploidy = 1)} Creates a GCAdjustParams object. \describe{ \item{\code{genome}}{A \code{\linkS4class{BSgenome}} object of the species that the experiment was done for.} \item{\code{mappability}}{A \code{\linkS4class{BSgenome}} object, containing the mappability of each base in the genome.} \item{\code{min.mappability}}{A number between 0 and 100 that is a cutoff on window mappability.} \item{\code{n.bins}}{The number of GC content bins to divide the windows into, before finding the mode of counts in each window.} \item{\code{min.bin.size}}{GC bins with less than this many count windows inside them will be ignored.} \item{\code{poly.degree}}{The degree of the polynomial to fit to the GC bins' count modes.} \item{\code{ploidy}}{A vector of multipliers to use on the estimated absolute copy number of each sample, if the number of sets of chromosomes is known.} } } } } \author{Dario Strbenac}