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### Running command:
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###   /Library/Frameworks/R.framework/Resources/bin/R CMD check --install=check:Qtlizer.install-out.txt --library=/Library/Frameworks/R.framework/Resources/library --no-vignettes --timings Qtlizer_1.20.0.tar.gz
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* using log directory ‘/Users/biocbuild/bbs-3.20-bioc/meat/Qtlizer.Rcheck’
* using R version 4.4.1 (2024-06-14)
* using platform: aarch64-apple-darwin20
* R was compiled by
    Apple clang version 14.0.0 (clang-1400.0.29.202)
    GNU Fortran (GCC) 12.2.0
* running under: macOS Ventura 13.6.7
* using session charset: UTF-8
* using option ‘--no-vignettes’
* checking for file ‘Qtlizer/DESCRIPTION’ ... OK
* this is package ‘Qtlizer’ version ‘1.20.0’
* package encoding: UTF-8
* checking package namespace information ... OK
* checking package dependencies ...Warning: unable to access index for repository https://CRAN.R-project.org/src/contrib:
  cannot open URL 'https://CRAN.R-project.org/src/contrib/PACKAGES'
 OK
* checking if this is a source package ... OK
* checking if there is a namespace ... OK
* checking for hidden files and directories ... OK
* checking for portable file names ... OK
* checking for sufficient/correct file permissions ... OK
* checking whether package ‘Qtlizer’ can be installed ... OK
* checking installed package size ... OK
* checking package directory ... OK
* checking ‘build’ directory ... OK
* checking DESCRIPTION meta-information ... OK
* checking top-level files ... OK
* checking for left-over files ... OK
* checking index information ... OK
* checking package subdirectories ... OK
* checking code files for non-ASCII characters ... OK
* checking R files for syntax errors ... OK
* checking whether the package can be loaded ... OK
* checking whether the package can be loaded with stated dependencies ... OK
* checking whether the package can be unloaded cleanly ... OK
* checking whether the namespace can be loaded with stated dependencies ... OK
* checking whether the namespace can be unloaded cleanly ... OK
* checking whether startup messages can be suppressed ... OK
* checking dependencies in R code ... OK
* checking S3 generic/method consistency ... OK
* checking replacement functions ... OK
* checking foreign function calls ... OK
* checking R code for possible problems ... NOTE
File ‘Qtlizer/R/zzz.R’:
  .onLoad calls:
    packageStartupMessage("\n  ---------\n  \n  For example usage please run: vignette('Qtlizer')\n  \n  Web-based GUI: http://genehopper.de/qtlizer\n  Documentation: http://genehopper.de/help#qtlizer_docu\n  Github Repo: https://github.com/matmu/Qtlizer\n  \n  Citation appreciated:\n  Munz M, Wohlers I, Simon E, Reinberger T, Busch H, Schaefer A and Erdmann J (2020) Qtlizer: comprehensive QTL annotation of GWAS results. Scientific Reports. doi:10.1038/s41598-020-75770-7\n  \n  ---------",     domain = NULL, appendLF = TRUE)

See section ‘Good practice’ in '?.onAttach'.
* checking Rd files ... OK
* checking Rd metadata ... OK
* checking Rd cross-references ... OK
* checking for missing documentation entries ... OK
* checking for code/documentation mismatches ... OK
* checking Rd \usage sections ... OK
* checking Rd contents ... OK
* checking for unstated dependencies in examples ... OK
* checking files in ‘vignettes’ ... OK
* checking examples ... ERROR
Running examples in ‘Qtlizer-Ex.R’ failed
The error most likely occurred in:

> base::assign(".ptime", proc.time(), pos = "CheckExEnv")
> ### Name: get_qtls
> ### Title: Query Qtlizer
> ### Aliases: get_qtls
> 
> ### ** Examples
> 
> get_qtls("rs4284742")
1 unique query term(s) found
Retrieving QTL information from Qtlizer...
Error in FUN(X[[i]], ...) : Web server seems to be down. Try again later!
Calls: get_qtls -> lapply -> FUN
Execution halted
* checking for unstated dependencies in vignettes ... OK
* checking package vignettes ... OK
* checking running R code from vignettes ... SKIPPED
* checking re-building of vignette outputs ... SKIPPED
* checking PDF version of manual ... OK
* DONE

Status: 1 ERROR, 1 NOTE
See
  ‘/Users/biocbuild/bbs-3.20-bioc/meat/Qtlizer.Rcheck/00check.log’
for details.