SomaticSignatures

This is the development version of SomaticSignatures; for the stable release version, see SomaticSignatures.

Somatic Signatures


Bioconductor version: Development (3.21)

The SomaticSignatures package identifies mutational signatures of single nucleotide variants (SNVs). It provides a infrastructure related to the methodology described in Nik-Zainal (2012, Cell), with flexibility in the matrix decomposition algorithms.

Author: Julian Gehring

Maintainer: Julian Gehring <jg-bioc at gmx.com>

Citation (from within R, enter citation("SomaticSignatures")):

Installation

To install this package, start R (version "4.5") and enter:


if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

# The following initializes usage of Bioc devel
BiocManager::install(version='devel')

BiocManager::install("SomaticSignatures")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("SomaticSignatures")
SomaticSignatures HTML R Script
Reference Manual PDF
NEWS Text
LICENSE Text

Details

biocViews Clustering, GenomicVariation, Sequencing, Software, SomaticMutation, StatisticalMethod, Visualization
Version 2.43.0
In Bioconductor since BioC 2.14 (R-3.1) (10.5 years)
License MIT + file LICENSE
Depends R (>= 3.5.0), VariantAnnotation, GenomicRanges, NMF
Imports S4Vectors, IRanges, GenomeInfoDb, Biostrings, ggplot2, ggbio, reshape2, NMF, pcaMethods, Biobase, methods, proxy
System Requirements
URL https://github.com/juliangehring/SomaticSignatures
Bug Reports https://support.bioconductor.org
See More
Suggests testthat, knitr, parallel, BSgenome.Hsapiens.1000genomes.hs37d5, SomaticCancerAlterations, ggdendro, fastICA, sva
Linking To
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Package Archives

Follow Installation instructions to use this package in your R session.

Source Package SomaticSignatures_2.43.0.tar.gz
Windows Binary (x86_64) SomaticSignatures_2.43.0.zip
macOS Binary (x86_64)
macOS Binary (arm64)
Source Repository git clone https://git.bioconductor.org/packages/SomaticSignatures
Source Repository (Developer Access) git clone git@git.bioconductor.org:packages/SomaticSignatures
Bioc Package Browser https://code.bioconductor.org/browse/SomaticSignatures/
Package Short Url https://bioconductor.org/packages/SomaticSignatures/
Package Downloads Report Download Stats