Changes in version 2.23.1 o Added unified lifecourse 19 immune cell-type reference matrix for 450k and EPIC arrays. Changes in version 2.15.0 o Add 12 blood cell-type DNAm reference matrix for 450k and EPIC arrays. Changes in version 2.0.0 o Add CellDMC and hepidish functions. Changes in version 0.99.0 o Initial submission to Bioconductor. o Added NEWS file. o Added constraint mode parameter in CP mode.