BulkSignalR

This is the development version of BulkSignalR; to use it, please install the devel version of Bioconductor.

Infer Ligand-Receptor Interactions from bulk expression (transcriptomics/proteomics) data, or spatial transcriptomics


Bioconductor version: Development (3.21)

Inference of ligand-receptor (LR) interactions from bulk expression (transcriptomics/proteomics) data, or spatial transcriptomics. BulkSignalR bases its inferences on the LRdb database included in our other package, SingleCellSignalR available from Bioconductor. It relies on a statistical model that is specific to bulk data sets. Different visualization and data summary functions are proposed to help navigating prediction results.

Author: Jacques Colinge [aut] (ORCID: ), Jean-Philippe Villemin [cre] (ORCID: )

Maintainer: Jean-Philippe Villemin <jpvillemin at gmail.com>

Citation (from within R, enter citation("BulkSignalR")):

Installation

To install this package, start R (version "4.5") and enter:


if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

# The following initializes usage of Bioc devel
BiocManager::install(version='devel')

BiocManager::install("BulkSignalR")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("BulkSignalR")
BulkSignalR-Differential HTML R Script
BulkSignalR-Main HTML R Script
Reference Manual PDF
NEWS Text
LICENSE Text

Details

biocViews Network, NetworkInference, Proteomics, RNASeq, Software, Spatial, Transcriptomics
Version 0.99.22
In Bioconductor since BioC 3.21 (R-4.5)
License CeCILL | file LICENSE
Depends R (>= 4.5)
Imports BiocFileCache, httr, DBI, RSQLite, cli, curl, dplyr, rlang, jsonlite, matrixStats, methods, doParallel, glmnet, ggalluvial, ggplot2, gridExtra, grid, Rtsne, ggrepel, foreach, multtest, igraph, orthogene, stabledist, circlize (>= 0.4.14), ComplexHeatmap(>= 2.0.0), stats, scales, RANN, SpatialExperiment, SummarizedExperiment, tools
System Requirements
URL https://github.com/ZheFrench/BulkSignalR
Bug Reports https://github.com/ZheFrench/BulkSignalR/issues
See More
Suggests knitr, markdown, rmarkdown, STexampleData, testthat (>= 3.0.0), codetools, Matrix, lattice, cluster, survival, MASS, nlme
Linking To
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Build Report Build Report

Package Archives

Follow Installation instructions to use this package in your R session.

Source Package BulkSignalR_0.99.22.tar.gz
Windows Binary (x86_64) BulkSignalR_0.99.22.zip (64-bit only)
macOS Binary (x86_64) BulkSignalR_0.99.22.tgz
macOS Binary (arm64) BulkSignalR_0.99.22.tgz
Source Repository git clone https://git.bioconductor.org/packages/BulkSignalR
Source Repository (Developer Access) git clone git@git.bioconductor.org:packages/BulkSignalR
Bioc Package Browser https://code.bioconductor.org/browse/BulkSignalR/
Package Short Url https://bioconductor.org/packages/BulkSignalR/
Package Downloads Report Download Stats