Blocks Search Results

Introduction

BLKPROB Version 4/ 8/99.1 Database=../data-blplus/blocks.dat ___________ ___________ ___________ |\ __________\ |___________| /__________ /| | | | | | | | | | | **********| |***********| |********** | | | | * BLOCKS | |EMAIL & WWW| |SEARCHER * | | | | **********| |***********| |********** | | \|___________|___________|___________|___________|___________|/ |\ __________\ /__________ /| | | blocks@ | | http:// | | | | blocks. | | blocks. | | | | fhcrc. | | fhcrc. | | | | org | | org | | \|___________| |___________|/ Here are your search results. The database searched was Blocks+ (19 Mar 99) which includes: BLOCKS 11.0 consisting of 4034 blocks representing 994 groups documented in PROSITE 15, plus 2277 blocks from 352 groups documented in PRINTS 22.0 but not represented in BLOCKS, plus 1083 blocks from 254 groups documented in PFAM 3.4 but not represented in BLOCKS or PRINTS, plus 1035 blocks from 268 groups documented in PRODOM 36 but not represented in BLOCKS, PRINTS or PFAM, plus 480 blocks from 127 groups documented in DOMO 2.0 but not represented in BLOCKS, PRINTS, PFAM or PRODOM for a total of 8909 blocks from 1995 groups. Get more information at http://blocks.fhcrc.org. If you found the Blocks Searcher useful, please cite: S Henikoff & JG Henikoff, "Protein family classification based on searching a database of blocks", Genomics 19:97-107 (1994). ============================================================================== Each numbered result consists of one or more blocks from a Prosite group found in the query sequence. One set of the highest-scoring blocks that are in the correct order and separated by distances comparable to the Blocks database is selected for analysis. If this set includes multiple blocks the probability that the lower scoring blocks support the highest scoring block is reported. Maps of the database blocks and query sequence are shown: AAA represents the first block roughly in proportion to its width. : represents the minimum distance between blocks in the database. . represents the maximum distance between blocks in the database. < > indicate the sequence has been truncated to fit the page. The query map is aligned on the highest scoring block. Multiple block hits that are consistent with the highest scoring block are separated by colons. Block hits that are not consistent are mapped below. The alignment of the query sequence with the sequence closest to it in the BLOCKS database is shown. The distance between detected blocks is listed as (min, max): for the database entry followed by the distance in the query. Upper case in the query indicates at least one occurrence of the residue in that column of the block. For interpretation of block hits, you might find it worthwhile to obtain the full set of blocks and documentation for a group. To do this, send a blank message to blocks@blocks.fhcrc.org with the subject heading: GET BL????? e.g., 'Subject: GET BL00044' (0s are zeros) for full information on this group. ============================================================================= Note: For searches using DNA queries, "Location" refers to the position in the query in base pairs from 5' to 3' on the + strand, whereas the map and alignment show the translated position in amino acid residues as before. =============================================================================

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Hits

Query=gi|2332305|gb|AA560840|AA560840 vk94e04.r1 Knowles Solter mouse blastocyst B1 M Size=642 Base Pairs Blocks Searched=8909 Alignments Done=12815646 Cutoff Expected Value= 2 ============================================================================== Anchor Combined Family Strand Blocks E-value E-value BL50040 Elongation factor 1 gamma chain pro 1 3 of 7 7.9e-32 5.5e-65 DM01181 7 kw 103-1A LACTOYLGLUTATHIONE GLUT 1 1 of 3 4.8e-05 4.6e-05 PF00043 Glutathione S-transferases. 1 1 of 1 0.0028 0.0026 BL00702 Granulocyte-macrophage colony-stimu 1 1 of 4 0.24 0.22 BL00421 Transmembrane 4 family proteins. 1 1 of 5 0.47 0.42 PR00614 NI-FE HYDROGENASE SMALL SUBUNIT SIG 1 1 of 11 0.77 0.71 BL00415 Synapsins proteins. 1 1 of 19 2.1 2 ============================================================================== >BL50040 3/7 blocks: Elongation factor 1 gamma chain profile. Block Frame Location (bp) Position p-value BL50040A 3 6-39 1.7e-14 BL50040B 2 152-227 7.2e-30 BL50040C 1 397-523 1.2e-38 Other reported alignments: |--- 186 amino acids---| BL50040 AA:::..BBB::::::...CCCCCC::::::::::...DDDDDDDEEEEEEEFFFFF.G gi AA:::::BBB::::::::CCCCCC BL50040A <->A (2,3):1 BL50040B A<->B (25,37):37 EF1G_HUMAN 4 GTLYTYPENWRA EF1G_HUMAN 53 FPAGKVPAFEGDDGFCVFESNAIAYY |||||||||||| |||||||||||||||||||||||||| gi 2 GTLYTYPENWRA gi 51 FPAGKVPAFEGDDGFCVFESNAIAYY BL50040C B<->C (47,66):56 EF1G_RABIT 135 VKRILGLLDAHLKTRTFLVGERVTLADITVVCTLLWLYKQVLE ||||||||| ||||||||||||||||||||||||||||||||| gi 133 VKRILGLLDtHLKTRTFLVGERVTLADITVVCTLLWLYKQVLE ------------------------------------------------------------------------------ >DM01181 1/3 blocks: 7 kw 103-1A LACTOYLGLUTATHIONE GLUTATHIONE LYASE. Block Frame Location (bp) Position p-value DM01181C 1 367-478 7.5e-12 Other reported alignments: |--- 63 amino acids---| DM01181 AAAAAAAAAAAAAAAAAAAAAA::::::...BBBBBBBBB::::.CCCCCCCCCCCCCCC gi <::::::::::::::::::::::::::::::::::::::::::::CCCCCCCCCCCCCCC DM01181C <->C (112,128):122 GTX1_TOBAC 115 GEEQEKDKEEVCEMLKVLDNELKDKKFFVGDKFGFADI | |||| | || || | || ||| gi 123 kqAtEnAKEEVkrILgLLDthLKtRTFlVGErVtLADI ------------------------------------------------------------------------------ >PF00043 1/1 blocks: Glutathione S-transferases. Block Frame Location (bp) Position p-value PF00043 2 164-251 4.4e-10 Up to 1 repeats expected: PF00043 2 167-254 8.5e-07 Other reported alignments: PF00043 <-> EF1G_HUMAN 57 KVPAFEGDDGFCVFESNAIAYYVSNEELRG |||||||||||||||||||||||||||||| gi 55 KVPAFEGDDGFCVFESNAIAYYVSNEELRG 56 VPAFEGDDGFCVFESNAIAYYVSNEELRGS ------------------------------------------------------------------------------ >BL00702 1/4 blocks: Granulocyte-macrophage colony-stimulating factor proteins. Block Frame Location (bp) Position p-value BL00702B 1 430-532 3.7e-08 Other reported alignments: |--- 60 amino acids---| BL00702 AAAAAAAAAAAAAAAAA:::.BBBBBBBBBBBBBBBCCCCCCCCCCCCDDDDDDDDDDDD gi <::::::::::::::::::::BBBBBBBBBBBBBBB BL00702B <->B (32,52):143 CSF2_PIG 53 MNETVDVVCEMFDPQEPTCVQTRLNLYKQGLRGSL | | | | | | |||| | | gi 144 LktrTflVgErvtLadiTvVcTlLwLYKQvLepSF ------------------------------------------------------------------------------ >BL00421 1/5 blocks: Transmembrane 4 family proteins. Block Frame Location (bp) Position p-value BL00421C 2 479-512 7.3e-08 Other reported alignments: |--- 107 amino acids---| BL00421 AAAA:::::::..BBBBBBBBB::::::::::..CCC:....D::.........EEEEEEE gi <:::::::::::::::::::::::::::::::::CCC BL00421C <->C (132,154):159 C151_HUMAN 149 LQQEFHCCGSNN || |||| | gi 160 LQlSVpCCGSiN ------------------------------------------------------------------------------ >PR00614 1/11 blocks: NI-FE HYDROGENASE SMALL SUBUNIT SIGNATURE Block Frame Location (bp) Position p-value PR00614I 1 1-79 1.2e-07 Other reported alignments: |--- 112 amino acids---| PR00614 AAAAABBBBBB::::.CCCCC:.DDDEEEEEE:.FFFFFGGGGHHHH:IIIIIIJJJKKK gi IIIIII PR00614I <->I (204,283):0 MBHS_ALCHY 254 RKGYCLYKVGCKGPTTYNACSTTRWNG | | | || | || | | gi 1 RlGpCthtLkigGPsTsvrCSvQRgsG ------------------------------------------------------------------------------ >BL00415 1/19 blocks: Synapsins proteins. Block Frame Location (bp) Position p-value BL00415Q 1 40-145 3.3e-07 biased Other reported alignments: |--- 294 amino acids---| BL00415 AAABBBCCCDDDEEEFFFGGHHHHIIJJKKKKLLMMMNNNN::OOOPPPQQQRRRSSS gi :QQQ BL00415Q <->Q (594,596):13 SYN1_RAT 595 PAGPIRQASQAGPGPRTGPPTTQQPRPSGPGPAGRP | | | | ||| | | | | | gi 14 PstsvRcsvQrGsGPRalrtTplplwPnqPhP*isP ------------------------------------------------------------------------------ 7 possible hits reported

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