Package: GMAC
Type: Package
Title: Genomic Mediation Analysis with Adaptive Confounding Adjustment
Version: 3.1
Date: 2022-3-16
Author: Fan Yang, Jiebiao Wang and Lin Chen
Maintainer: Jiebiao Wang <randel.wang@gmail.com>
Description: Performs genomic mediation
    analysis with adaptive confounding adjustment (GMAC) proposed by Yang et al. (2017) <doi:10.1101/078683>. It implements large scale
    mediation analysis and adaptively selects potential confounding variables to
    adjust for each mediation test from a pool of candidate confounders. The package
    is tailored for but not limited to genomic mediation analysis (e.g., cis-gene
    mediating trans-gene regulation pattern where an eQTL, its cis-linking gene
    transcript, and its trans-gene transcript play the roles as treatment, mediator
    and the outcome, respectively), restricting to scenarios with the presence of
    cis-association (i.e., treatment-mediator association) and random eQTL (i.e.,
    treatment).
License: GPL
Depends: parallel
LazyData: TRUE
NeedsCompilation: no
Repository: CRAN
RoxygenNote: 7.1.2
Packaged: 2022-03-16 19:50:27 UTC; rande
Date/Publication: 2022-03-17 08:30:18 UTC
Built: R 4.2.0; ; 2022-04-24 01:27:05 UTC; windows
