## ---- include = FALSE--------------------------------------------------------- knitr::opts_chunk$set( collapse = TRUE, comment = "#>" ) ## ----setup-------------------------------------------------------------------- library(NBR) cmx <- NBR:::frontal3D # Load 3D array brain_labs <- NBR:::frontal_roi # Load node labels phen <- NBR:::frontal_phen # Load phenotypic info dim(cmx) # Show 3D array dimensions ## ----input networks, fig.align = "center"------------------------------------- library(lattice) avg_mx <- apply(cmx, 1:2, mean) # Set max-absolute value in order to set a color range centered in zero. flim <- max(abs(avg_mx)[is.finite(avg_mx)]) levelplot(avg_mx, main = "Average", ylab = "ROI", xlab = "ROI", at = seq(-flim, flim, length.out = 100)) ## ----input phenotypic info---------------------------------------------------- head(phen) nrow(phen) identical(nrow(phen), dim(cmx)[3]) ## ----group-based NBR---------------------------------------------------------- set.seed(18900217) # Because R. Fisher is my hero before <- Sys.time() nbr_group <- nbr_lm_aov(net = cmx, nnodes = 28, idata = phen, mod = "~ Group", thrP = 0.01, nperm = 10) after <- Sys.time() show(after-before) ## ----multicore group-based NBR, eval = FALSE---------------------------------- # set.seed(18900217) # library(parallel) # before <- Sys.time() # nbr_group <- nbr_lm_aov(net = cmx, nnodes = 28, idata = phen, # mod = "~ Group", thrP = 0.01, nperm = 100, cores = detectCores()) # after <- Sys.time() # length(nbr_group) ## ----component display, fig.align = "center"---------------------------------- # Plot significant component edge_mat <- array(0, dim(avg_mx)) edge_mat[nbr_group$components$Group[,2:3]] <- 1 levelplot(edge_mat, col.regions = rev(heat.colors(100)), main = "Component", ylab = "ROI", xlab = "ROI") show(nbr_group$fwe$Group)